Author details

Full Name

Leslie R Bridges

Affiliation

ORCID

Career Start Year

1986

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37644658	Cortical laminar necrosis mimicking leptomeningeal recurrence in a child with medulloblastoma and epilepsy.		2023
37645951	Replicating RNA as a component of scrapie fibrils.		2023
35086142	Vasculocentric Axonal NfH in Small Vessel Disease.	Journal of Neuropathology and Experimental Neurology	2022
36205142	Vascular Collagen Type-IV in Hypertension and Cerebral Small Vessel Disease.	Stroke	2022
34021421	Paraganglioma of the cauda equina: a tertiary centre experience and scoping review of the current literature.	Neurosurgical Review	2022
34618539	Integrated Molecular-Morphologic Meningioma Classification: A Multicenter Retrospective Analysis, Retrospectively and Prospectively Validated.	J Clin Oncol	2021
33900873	High grade gliomas in young children: The South Thames Neuro-Oncology unit experience and recent advances in molecular biology and targeted therapies.	Pediatric Hematology and Oncology	2021
34281379	Innate Immune Anti-Inflammatory Response in Human Spontaneous Intracerebral Hemorrhage.	Stroke	2021
33325069	A case series of Diffuse Glioneuronal Tumours with Oligodendroglioma-like features and Nuclear Clusters (DGONC).	Neuropathol Appl Neurobiol	2021
32829524	A functional long-term 2D serum-free human hepatic in vitro system for drug evaluation.	Biotechnology Progress	2021
31467148	Epstein-Barr virus associated CNS lymphoproliferative disorder after long-term immunosuppression.	Pract Neurol	2020
32076448	Encephalomyelitis with Retinopathy in Common Variable Immunodeficiency (CVID).	Neuro-Ophthalmology	2020
31786093	DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study.	Lancet Child Adolesc Health	2020
32238360	Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.	Cancer Discov	2020
32100099	Biallelic mutations in NRROS cause an early onset lethal microgliopathy.	Acta Neuropathol	2020
32670763	Differential Monocyte Actuation in a Three-Organ Functional Innate Immune System-on-a-Chip.	Advanced Science	2020
31520433	Foix-Chavany-Marie syndrome due to type E TDP43 pathology.	Neuropathology and Applied Neurobiology	2020
31402627	Rapid neuroinflammatory changes in human acute intracerebral hemorrhage.	Annals of Clinical and Translational Neurology	2019
35586798	Long-Term Electrical and Mechanical Function Monitoring of a Human-on-a-Chip System.	Advanced Functional Materials	2019
31553444	Cell Senescence and Cerebral Small Vessel Disease in the Brains of People Aged 80 Years and Older.	Journal of Neuropathology and Experimental Neurology	2019
30590671	The cGMP-Degrading Enzyme Phosphodiesterase-5 (PDE5) in Cerebral Small Arteries of Older People.	Journal of Neuropathology and Experimental Neurology	2019
30239258	Lesional and perilesional tissue characterization by automated image processing in a novel gyrencephalic animal model of peracute intracerebral hemorrhage.	Journal of Cerebral Blood Flow and Metabolism	2019
31270362	On the potential of in vitro organ-chip models to define temporal pharmacokinetic-pharmacodynamic relationships.	Scientific Reports	2019
31217335	Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics.	Science Translational Medicine	2019
30130706	Investigation of the effect of hepatic metabolism on off-target cardiotoxicity in a multi-organ human-on-a-chip system.	Biomaterials	2018
29967352	Functional diversity and cooperativity between subclonal populations of pediatric glioblastoma and diffuse intrinsic pontine glioma cells.	Nat Med	2018
27333085	Metastasising pleomorphic adenoma of the submandibular salivary gland presenting with spinal cord compression: case report and review of cases with CNS involvement.	British Journal of Neurosurgery	2017
28855392	Neuropathology of White Matter Lesions, Blood-Brain Barrier Dysfunction, and Dementia.	Stroke	2017
28529053	Unusual Intraparenchymal Pontomedullary Epidermoid Cyst in a 2-Year-Old Child: A Case Report and Review of the Literature.	World Neurosurgery	2017
28966033	Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma.	Cancer Cell	2017
28560662	MGMT promoter methylation status: time for a frank discussion.	Journal of Neuro-Oncology	2017
27029468	Rheumatoid meningitis.	Practical Neurology	2016
26837601	Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs.	Scientific Reports	2016
27143427	Age-dependent expression of VEGFR2 in deep brain arteries in small vessel disease, CADASIL, and healthy brains.	Neurobiology of Aging	2016
26922712	Whole exome sequence analysis reveals a homozygous mutation in PNPLA2 as the cause of severe dilated cardiomyopathy secondary to neutral lipid storage disease.	Int J Cardiol	2016
27180091	Pseudoprogression in children, adolescents and young adults with non-brainstem high grade glioma and diffuse intrinsic pontine glioma.	J Neurooncol	2016
25521176	Endothelial cells and human cerebral small vessel disease.	Brain Pathology	2015
24940569	A giant cause of stroke.	Acute Medicine	2014
25289893	Blood-brain barrier dysfunction and cerebral small vessel disease (arteriolosclerosis) in brains of older people.	Journal of Neuropathology and Experimental Neurology	2014
24189182	Anosmin-1 contributes to brain tumor malignancy through integrin signal pathways.		2014
23842286	Cerebral subcortical small vessel disease in subjects with pathologically confirmed Alzheimer disease: a clinicopathologic study in the Oxford Project to Investigate Memory and Ageing (OPTIMA).	Alzheimer Disease and Associated Disorders	2014
23376846	Heparin-binding epidermal growth factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia.	Oncogene	2014
24864019	Isolated intracranial Rosai-Dorfman disease in a child, a case report and review of the literature.	Child's Nervous System	2014
23580196	Heterozygous inactivation of tsc2 enhances tumorigenesis in p53 mutant zebrafish.	DMM Disease Models and Mechanisms	2013
24252243	Double-labelling immunohistochemistry for MGMT and a "cocktail" of non-tumourous elements is a reliable, quick and easy technique for inferring methylation status in glioblastomas and other primary brain tumours.	Acta neuropathologica communications	2013
23403376	An MRI-histological study of white matter in stroke-free SHRSP.	Journal of Cerebral Blood Flow and Metabolism	2013
23507393	Quantitative evaluation of MRI and histological characteristics of the 5xFAD Alzheimer mouse brain.	NeuroImage	2013
22170884	Neuropathologic evidence of endothelial changes in cerebral small vessel disease.	Neurology	2012
22918454	Devastating aquaporin-4 and HTLV-1-associated necrotizing encephalopathy.	Journal of Neurology	2012
22380956	Paciniolipoma in congenital spinal dysraphism.	Journal of Neurosurgery: Pediatrics	2012