Author details

Full Name

Veena Afzal

Affiliation

ORCID

Career Start Year

1984

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37425964	Cell Type- and Tissue-specific Enhancers in Craniofacial Development.	bioRxiv	2023
37081156	Topologically associating domain boundaries are required for normal genome function.	Commun Biol	2023
34913122	Characterization of Mammalian In Vivo Enhancers Using Mouse Transgenesis and CRISPR Genome Editing.	Methods Mol Biol	2022
33398137	Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development.	Nature	2021
33782603	Ultraconserved enhancer function does not require perfect sequence conservation.	Nat Genet	2021
32728245	The changing mouse embryo transcriptome at whole tissue and single-cell resolution.	Nature	2020
32169219	Comprehensive InÂ Vivo Interrogation Reveals Phenotypic Impact of Human Enhancer Variants.	Cell	2020
33037424	Author Correction: An atlas of dynamic chromatin landscapes in mouse fetal development.	Nature	2020
32737473	Supervised enhancer prediction with epigenetic pattern recognition and targeted validation.	Nat Methods	2020
31217582	Noncoding deletions reveal a gene that is critical for intestinal function.	Nature	2019
29497140	Author Correction: Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation.	Nat Neurosci	2018
29358049	Ultraconserved Enhancers Are Required for Normal Development.	Cell	2018
29434377	Single-nucleus analysis of accessible chromatin in developing mouse forebrain reveals cell-type-specific transcriptional regulation.	Nat Neurosci	2018
29420474	Enhancer redundancy provides phenotypic robustness in mammalian development.	Nature	2018
28827824	Limb-Enhancer Genie: An accessible resource of accurate enhancer predictions in the developing limb.	PLoS Comput Biol	2017
28671691	Germline Chd8 haploinsufficiency alters brain development in mouse.	Nat Neurosci	2017
27768887	Progressive Loss of Function in a Limb Enhancer during Snake Evolution.	Cell	2016
27703156	Genome-wide compendium and functional assessment of in vivo heart enhancers.	Nat Commun	2016
24658141	Function-based identification of mammalian enhancers using site-specific integration.	Nat Methods	2014
25188404	Tissue-specific RNA expression marks distant-acting developmental enhancers.	PLoS Genet	2014
24752179	Tissue-specific SMARCA4 binding at active and repressed regulatory elements during embryogenesis.	Genome Res	2014
23375746	A high-resolution enhancer atlas of the developing telencephalon.	Cell	2013
24360275	Rapid and pervasive changes in genome-wide enhancer usage during mammalian development.	Cell	2013
24159046	Fine tuning of craniofacial morphology by distant-acting enhancers.	Science	2013
22138689	Large-scale discovery of enhancers from human heart tissue.	Nat Genet	2011
20173736	Targeted deletion of the 9p21 non-coding coronary artery disease risk interval in mice.	Nature	2010
20729851	ChIP-Seq identification of weakly conserved heart enhancers.	Nat Genet	2010
19212405	ChIP-seq accurately predicts tissue-specific activity of enhancers.	Nature	2009
19268701	Functional autonomy of distant-acting human enhancers.	Genomics	2009
18176564	Ultraconservation identifies a small subset of extremely constrained developmental enhancers.	Nat Genet	2008
18772437	Human-specific gain of function in a developmental enhancer.	Science	2008
17803355	Deletion of ultraconserved elements yields viable mice.	PLoS Biol	2007
16769978	Close sequence comparisons are sufficient to identify human cis-regulatory elements.	Genome Res	2006
16964311	Knockdown expression and hepatic deficiency reveal an atheroprotective role for SR-BI in liver and peripheral tissues.	Journal of Clinical Investigation	2006
17086198	In vivo enhancer analysis of human conserved non-coding sequences.	Nature	2006
15859353	Comparative genomic analysis reveals a distant liver enhancer upstream of the COUP-TFII gene.	Mamm Genome	2005
15885503	In vivo characterization of a vertebrate ultraconserved enhancer.	Genomics	2005
15117734	Analysis of apolipoprotein A5, c3, and plasma triglyceride concentrations in genetically engineered mice.	Arterioscler Thromb Vasc Biol	2004
15496924	Megabase deletions of gene deserts result in viable mice.	Nature	2004
12842837	Regulation of the expression of the apolipoprotein(a) gene: evidence for a regulatory role of the 5' distal apolipoprotein(a) transcription control region enhancer in yeast artificial chromosome transgenic mice.	Arteriosclerosis, Thrombosis, and Vascular Biology	2003
14563999	Scanning human gene deserts for long-range enhancers.	Science	2003
11925569	Tenascin-X deficiency mimics Ehlers-Danlos syndrome in mice through alteration of collagen deposition.	Nature Genetics	2002
11279093	Regulation and activity of the human ABCA1 gene in transgenic mice.	Journal of Biological Chemistry	2001
11526400	Deletion of a coordinate regulator of type 2 cytokine expression in mice.	Nature Immunology	2001
10070969	Increased ultraviolet sensitivity and chromosomal instability related to P53 function in the xeroderma pigmentosum variant.	Cancer Research	1999
9927493	Protein 4.1R-deficient mice are viable but have erythroid membrane skeleton abnormalities.	Journal of Clinical Investigation	1999
8650167	Segregation of DNA polynucleotide strands into sister chromatids and the use of endoreduplicated cells to track sister chromatid exchanges induced by crosslinks, alkylations, or x-ray damage.	Proceedings of the National Academy of Sciences of the United States of America	1996
8671736	Chromatid exchanges may be induced by damage in sites of transcriptional activity.	Mutagenesis	1996
8544762	Sister chromatid exchanges in cells defective in mismatch, post-replication and excision repair.	Mutagenesis	1995
7689156	Depletion of cellular polyamines by alpha-difluoromethylornithine increases 1,3-bis(2-chloroethyl)-1-nitrosourea-induced sister-chromatid exchanges.	Mutation Research	1993