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Author Details

Cassie Kline
Children's Hospital of Philadelphia
2008
56
18
PMIDPaper TitleJournal TitlePublished Year
37978284The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial.Nat Med2024
38039965A road map for the treatment of pediatric diffuse midline glioma.Cancer Cell2024
37978284The type II RAF inhibitor tovorafenib in relapsed/refractory pediatric low-grade glioma: the phase 2 FIREFLY-1 trial.Nat Med2024
38039965A road map for the treatment of pediatric diffuse midline glioma.Cancer Cell2024
36124689Response assessment in pediatric craniopharyngioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) Working Group.Neuro Oncol2023
36124689Response assessment in pediatric craniopharyngioma: recommendations from the Response Assessment in Pediatric Neuro-Oncology (RAPNO) Working Group.Neuro Oncol2023
37584601Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.Cancer Discov2023
37810231Sex-related incidence and survival differences in pediatric high-grade glioma subtypes: A population-based cohort study.iScience2023
36711966Automated Tumor Segmentation and Brain Tissue Extraction from Multiparametric MRI of Pediatric Brain Tumors: A Multi-Institutional Study.medRxiv2023
36649671Retrospective dataset and survey analyses identify gaps in data collection for craniopharyngioma and priorities of patients and families affected by the disease.Neoplasia2023
37318058PNOC015: Repeated convection-enhanced delivery of MTX110 (aqueous panobinostat) in children with newly diagnosed diffuse intrinsic pontine glioma.Neuro Oncol2023
36548930Outcomes of Infants and Young Children With Relapsed Medulloblastoma After Initial Craniospinal Irradiation-Sparing Approaches: An International Cohort Study.J Clin Oncol2023
37244226Translational considerations for immunotherapy clinical trials in pediatric neuro-oncology.Neoplasia2023
36738585Indigenous peoples and inclusion in clinical and genomic research: Understanding the history and navigating contemporary engagement.Neoplasia2023
37051331Automated tumor segmentation and brain tissue extraction from multiparametric MRI of pediatric brain tumors: A multi-institutional study.Neurooncol Adv2023
37492101OpenPBTA: The Open Pediatric Brain Tumor Atlas.Cell Genom2023
36916198Doing the Work to Improve Diversity in Pediatric Clinical Trials.Pediatrics2023
37584601Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways.Cancer Discov2023
37810231Sex-related incidence and survival differences in pediatric high-grade glioma subtypes: A population-based cohort study.iScience2023
37492101OpenPBTA: The Open Pediatric Brain Tumor Atlas.Cell Genom2023
37318058PNOC015: Repeated convection-enhanced delivery of MTX110 (aqueous panobinostat) in children with newly diagnosed diffuse intrinsic pontine glioma.Neuro Oncol2023
37051331Automated tumor segmentation and brain tissue extraction from multiparametric MRI of pediatric brain tumors: A multi-institutional study.Neurooncol Adv2023
37244226Translational considerations for immunotherapy clinical trials in pediatric neuro-oncology.Neoplasia2023
36548930Outcomes of Infants and Young Children With Relapsed Medulloblastoma After Initial Craniospinal Irradiation-Sparing Approaches: An International Cohort Study.J Clin Oncol2023
36649671Retrospective dataset and survey analyses identify gaps in data collection for craniopharyngioma and priorities of patients and families affected by the disease.Neoplasia2023
36916198Doing the Work to Improve Diversity in Pediatric Clinical Trials.Pediatrics2023
36711966Automated Tumor Segmentation and Brain Tissue Extraction from Multiparametric MRI of Pediatric Brain Tumors: A Multi-Institutional Study.medRxiv2023
36738585Indigenous peoples and inclusion in clinical and genomic research: Understanding the history and navigating contemporary engagement.Neoplasia2023
35137228Serial H3K27M cell-free tumor DNA (cf-tDNA) tracking predicts ONC201 treatment response and progression in diffuse midline glioma.Neuro Oncol2022
35814456An Integrated Analysis of Clinical, Genomic, and Imaging Features Reveals Predictors of Neurocognitive Outcomes in a Longitudinal Cohort of Pediatric Cancer Survivors, Enriched with CNS Tumors (Rad ART Pro).Front Oncol2022
36068285Circulating tumor DNA sequencing provides comprehensive mutation profiling for pediatric central nervous system tumors.NPJ Precis Oncol2022
35615720A Survey of Patient-Relevant Outcomes in Pediatric Craniopharyngioma: Focus on Hypothalamic Obesity.Front Endocrinol (Lausanne)2022
36382108Phase I dose escalation and expansion trial of single agent ONC201 in pediatric diffuse midline gliomas following radiotherapy.Neurooncol Adv2022
35852795Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker Outcomes from PNOC003.Clin Cancer Res2022
35137228Serial H3K27M cell-free tumor DNA (cf-tDNA) tracking predicts ONC201 treatment response and progression in diffuse midline glioma.Neuro Oncol2022
35615720A Survey of Patient-Relevant Outcomes in Pediatric Craniopharyngioma: Focus on Hypothalamic Obesity.Front Endocrinol (Lausanne)2022
35852795Upfront Biology-Guided Therapy in Diffuse Intrinsic Pontine Glioma: Therapeutic, Molecular, and Biomarker Outcomes from PNOC003.Clin Cancer Res2022
35814456An Integrated Analysis of Clinical, Genomic, and Imaging Features Reveals Predictors of Neurocognitive Outcomes in a Longitudinal Cohort of Pediatric Cancer Survivors, Enriched with CNS Tumors (Rad ART Pro).Front Oncol2022
36068285Circulating tumor DNA sequencing provides comprehensive mutation profiling for pediatric central nervous system tumors.NPJ Precis Oncol2022
36382108Phase I dose escalation and expansion trial of single agent ONC201 in pediatric diffuse midline gliomas following radiotherapy.Neurooncol Adv2022
33272950Pilot Study of Hyperpolarized <sup>13</sup>C Metabolic Imaging in Pediatric Patients with Diffuse Intrinsic Pontine Glioma and Other CNS Cancers.AJNR Am J Neuroradiol2021
34277419Radiation in Combination With Targeted Agents and Immunotherapies for Pediatric Central Nervous System Tumors - Progress, Opportunities, and Challenges.Front Oncol2021
34244769Understanding the global impact of primary brain tumors: The untapped potential of population-based cancer registries.Neuro Oncol2021
33272950Pilot Study of Hyperpolarized <sup>13</sup>C Metabolic Imaging in Pediatric Patients with Diffuse Intrinsic Pontine Glioma and Other CNS Cancers.AJNR Am J Neuroradiol2021
34277419Radiation in Combination With Targeted Agents and Immunotherapies for Pediatric Central Nervous System Tumors - Progress, Opportunities, and Challenges.Front Oncol2021
34244769Understanding the global impact of primary brain tumors: The untapped potential of population-based cancer registries.Neuro Oncol2021
31104347High-grade neuroepithelial tumor with BCOR exon 15 internal tandem duplication-a comprehensive clinical, radiographic, pathologic, and genomic analysis.Brain Pathol2020
32257279Neuro-Oncology Practice Clinical Debate: targeted therapy vs conventional chemotherapy in pediatric low-grade glioma.Neurooncol Pract2020
32303840Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition.Acta Neuropathol2020
32392601Neurocognitive Outcomes in Children with Brain Tumors.Semin Neurol2020
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Collaborators

University Children's Hospital Zurich
Co-authored papers 33
University of California san francisco
Co-authored papers 16
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Co-authored papers 11
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Co-authored papers 10
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Co-authored papers 10
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Co-authored papers 9
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Co-authored papers 8
USA University of Zurich
Co-authored papers 8
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Co-authored papers 8
Co-authored papers 7
University of California san francisco
Co-authored papers 7
Brain Tumor Institute, Children's National Hospital
Co-authored papers 7
Co-authored papers 6
University of Michigan-Ann Arbor
Co-authored papers 6
Children's National Hospital
Co-authored papers 6
Co-authored papers 5
Ann & Robert H. Lurie Children's Hospital
Co-authored papers 5
University of California san francisco
Co-authored papers 5
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Co-authored papers 4
University of California san francisco
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