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Author Details

Paul Haluska
Mayo Clinic
1996
91
40
PMIDPaper TitleJournal TitlePublished Year
34515877Phase I study of cediranib, an oral VEGFR inhibitor, in combination with selumetinib, an oral MEK inhibitor, in patients with advanced solid malignancies.Invest New Drugs2022
34316715Characterization of a <i>RAD51C</i>-silenced high-grade serous ovarian cancer model during development of PARP inhibitor resistance.NAR Cancer2021
33852121Randomized Phase II Trial of Capecitabine and Lapatinib with or without IMC-A12 (Cituxumumab) in Patients with HER2-Positive Advanced Breast Cancer Previously Treated with Trastuzumab and Chemotherapy: NCCTG N0733 (Alliance).Breast Cancer Res Treat2021
33850213Statistical analysis of comparative tumor growth repeated measures experiments in the ovarian cancer patient derived xenograft (PDX) setting.Sci Rep2021
34642026Results of TRIO-14, a phase II, multicenter, randomized, placebo-controlled trial of carboplatin-paclitaxel versus carboplatin-paclitaxel-ganitumab in newly diagnosed epithelial ovarian cancer.Gynecol Oncol2021
34611148Ganitumab and metformin plus standard neoadjuvant therapy in stage 2/3 breast cancer.NPJ Breast Cancer2021
32260077Disruption of Glycogen Utilization Markedly Improves the Efficacy of Carboplatin against Preclinical Models of Clear Cell Ovarian Carcinoma.Cancers (Basel)2020
31787526Phase 1 trial of Vismodegib and Erlotinib combination in metastatic pancreatic cancer.Pancreatology2020
32104500Anti-CDCP1 immuno-conjugates for detection and inhibition of ovarian cancer.Theranostics2020
32816943Phase I and Pharmacokinetic Study of Romidepsin in Patients with Cancer and Hepatic Dysfunction: A National Cancer Institute Organ Dysfunction Working Group Study.Clin Cancer Res2020
32554541Development and Validation of the Gene Expression Predictor of High-grade Serous Ovarian Carcinoma Molecular SubTYPE (PrOTYPE).Clin Cancer Res2020
32473302Prognostic gene expression signature for high-grade serous ovarian cancer.Ann Oncol2020
31004097Gene expression differences between matched pairs of ovarian cancer patient tumors and patient-derived xenografts.Sci Rep2019
29138343A Phase I Clinical Trial of the Poly(ADP-ribose) Polymerase Inhibitor Veliparib and Weekly Topotecan in Patients with Solid Tumors.Clin Cancer Res2018
29788332Constitutive Interferon Pathway Activation in Tumors as an Efficacy Determinant Following Oncolytic Virotherapy.J Natl Cancer Inst2018
28073843Active Estrogen Receptor-alpha Signaling in Ovarian Cancer Models and Clinical Specimens.Clin Cancer Res2017
28461031Phase 2 trial of everolimus and letrozole in relapsed estrogen receptor-positive high-grade ovarian cancers.Gynecol Oncol2017
28423358Characterization of fusion genes in common and rare epithelial ovarian cancer histologic subtypes.Oncotarget2017
28658648Prevention of Human Lymphoproliferative Tumor Formation in Ovarian Cancer Patient-Derived Xenografts.Neoplasia2017
26946093High expression of orphan nuclear receptor NR4A1 in a subset of ovarian tumors with worse outcome.Gynecol Oncol2016
26324738Clinical and Translational Results of a Phase II, Randomized Trial of an Anti-IGF-1R (Cixutumumab) in Women with Breast Cancer That Progressed on Endocrine Therapy.Clin Cancer Res2016
26581242A First-in-Human Phase I Study of the Oral p38 MAPK Inhibitor, Ralimetinib (LY2228820 Dimesylate), in Patients with Advanced Cancer.Clin Cancer Res2016
27765027Ridaforolimus (MK-8669) synergizes with Dalotuzumab (MK-0646) in hormone-sensitive breast cancer.BMC Cancer2016
27614696In vivo anti-tumor activity of the PARP inhibitor niraparib in homologous recombination deficient and proficient ovarian carcinoma.Gynecol Oncol2016
25398436Oncolytic measles virus expressing the sodium iodide symporter to treat drug-resistant ovarian cancer.Cancer Res2015
26408297Molecular and clinical implementations of ovarian cancer mouse avatar models.Chin Clin Oncol2015
26217584Understanding the Key to Targeting the IGF Axis in Cancer: A Biomarker Assessment.Front Oncol2015
25962155Conventional chemotherapy and oncogenic pathway targeting in ovarian carcinosarcoma using a patient-derived tumorgraft.PLoS One2015
25712686The Neoadjuvant Model Is Still the Future for Drug Development in Breast Cancer.Clin Cancer Res2015
25695953A novel neutralizing antibody targeting pregnancy-associated plasma protein-a inhibits ovarian cancer growth and ascites accumulation in patient mouse tumorgrafts.Mol Cancer Ther2015
25783201Prioritizing therapeutic targets using patient-derived xenograft models.Biochim Biophys Acta2015
25779953TBCRC 019: A Phase II Trial of Nanoparticle Albumin-Bound Paclitaxel with or without the Anti-Death Receptor 5 Monoclonal Antibody Tigatuzumab in Patients with Triple-Negative Breast Cancer.Clin Cancer Res2015
23340390Intrathecal metastases causing conus medullaris syndrome.QJM2014
25290091A parallel-arm phase I trial of the humanised anti-IGF-1R antibody dalotuzumab in combination with the AKT inhibitor MK-2206, the mTOR inhibitor ridaforolimus, or the NOTCH inhibitor MK-0752, in patients with advanced solid tumours.Br J Cancer2014
25318936Pharmacokinetics of endoxifen and tamoxifen in female mice: implications for comparative in vivo activity studies.Cancer Chemother Pharmacol2014
25016924A phase II study of ramucirumab (IMC-1121B) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma.Gynecol Oncol2014
25123819Can we unlock the potential of IGF-1R inhibition in cancer therapy?Cancer Treat Rev2014
24857111Patient-derived xenograft models in gynecologic malignancies.Am Soc Clin Oncol Educ Book2014
24619793North Central Cancer Treatment Group/Alliance trial N08CA-the use of glutathione for prevention of paclitaxel/carboplatin-induced peripheral neuropathy: a phase 3 randomized, double-blind, placebo-controlled study.Cancer2014
24398046Tumorgrafts as in vivo surrogates for women with ovarian cancer.Clin Cancer Res2014
24390424Phase 1b study of safety, tolerability and efficacy of R1507, a monoclonal antibody to IGF-1R in combination with multiple standard oncology regimens in patients with advanced solid malignancies.Cancer Chemother Pharmacol2014
23934194Epithelial ovarian cancer experimental models.Oncogene2014
23470967Developing safety criteria for introducing new agents into neoadjuvant trials.Clin Cancer Res2013
24363999Patient-derived xenograft models to improve targeted therapy in epithelial ovarian cancer treatment.Front Oncol2013
24130056Dual HER/VEGF receptor targeting inhibits in vivo ovarian cancer tumor growth.Mol Cancer Ther2013
23605083A phase I trial of the IGF-1R antibody Cixutumumab in combination with temsirolimus in patients with metastatic breast cancer.Breast Cancer Res Treat2013
23796991Two birds with one stone: octreotide treatment for acromegaly and breast cancer.J Clin Oncol2013
21881915Phase I study of temsirolimus in combination with EKB-569 in patients with advanced solid tumors.Invest New Drugs2012
23169510Adaptive trials in the neoadjuvant setting: a model to safely tailor care while accelerating drug development.J Clin Oncol2012
23045324Hormone response in ovarian cancer: time to reconsider as a clinical target?Endocr Relat Cancer2012
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Collaborators

Mayo Clinic
Co-authored papers 19
Mayo Clinic
Co-authored papers 12
Co-authored papers 7
Mayo Clinic
Co-authored papers 5
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MD Anderson Cancer Center
Co-authored papers 4
Co-authored papers 4
The Institute for Cancer Research
Co-authored papers 4
Mayo Clinic College of Medicine
Co-authored papers 4
Mayo Clinic
Co-authored papers 4
Co-authored papers 3
Ovarian Cancer Action Research Centre, Imperial College London
Co-authored papers 3
David Geffen School of Medicine at university of california los angeles
Co-authored papers 3
Center for Individualized Medicine, Mayo Clinic
Co-authored papers 3
Mayo Clinic
Co-authored papers 3
University of California San Francisco
Co-authored papers 3
Mayo Clinic
Co-authored papers 3
Mayo Clinic
Co-authored papers 3
Mayo Clinic
Co-authored papers 3
Cedars-Sinai Medical Center
Co-authored papers 3
University of Minnesota
Co-authored papers 3
Co-authored papers 3
The Royal Marsden NHS Foundation Trust and Institute of Cancer Research
Co-authored papers 3
Otto-Friedrich-University Bamberg
Co-authored papers 3
University Hospital
Co-authored papers 3
Buck Institute for Research on Aging
Co-authored papers 3
University Claude Bernard Lyon I
Co-authored papers 3
David Geffen School of Medicine at University of California Los Angeles
Co-authored papers 3
Co-authored papers 3
Peter MacCallum Cancer Centre
Co-authored papers 2