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Author Details

Lukas Habegger
2005
35
27
PMIDPaper TitleJournal TitlePublished Year
34906480Medical manifestations and health care utilization among adult MyCode participants with neurodevelopmental psychiatric copy number variants.Genet Med2022
34662886Exome sequencing and analysis of 454,787 UK Biobank participants.Nature2021
34017140Computationally efficient whole-genome regression for quantitative and binary traits.Nat Genet2021
34115965Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals.Am J Hum Genet2021
33619501Genome-wide analysis in 756,646 individuals provides first genetic evidence that <i>ACE2</i> expression influences COVID-19 risk and yields genetic risk scores predictive of severe disease.medRxiv2021
33655273A catalog of associations between rare coding variants and COVID-19 outcomes.medRxiv2021
32697297Identification of Neuropsychiatric Copy Number Variants in a Health Care System Population.JAMA Psychiatry2020
33087929Exome sequencing and characterization of 49,960 individuals in the UK Biobank.Nature2020
29727688Profiling and Leveraging Relatedness in a Precision Medicine Cohort of 92,455 Exomes.Am J Hum Genet2018
29899519Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes.Nat Commun2018
28538136Genetic and Pharmacologic Inactivation of ANGPTL3 and Cardiovascular Disease.N Engl J Med2017
28008009Distribution and clinical impact of functional variants in 50,726 whole-exome sequences from the DiscovEHR study.Science2016
26933753Inactivating Variants in ANGPTL4 and Risk of Coronary Artery Disease.N Engl J Med2016
26382196CLAMMS: a scalable algorithm for calling common and rare copy number variants from exome sequencing data.Bioinformatics2016
23450794Accurate identification and analysis of human mRNA isoforms using deep long read sequencing.G3 (Bethesda)2013
24026178Analysis of variable retroduplications in human populations suggests coupling of retrotransposition to cell division.Genome Res2013
22238592IQSeq: integrated isoform quantification analysis based on next-generation sequencing.PLoS One2012
22797897Regulatory element copy number differences shape primate expression profiles.Proc Natl Acad Sci U S A2012
22743228VAT: a computational framework to functionally annotate variants in personal genomes within a cloud-computing environment.Bioinformatics2012
22344438A systematic survey of loss-of-function variants in human protein-coding genes.Science2012
22424236Personal omics profiling reveals dynamic molecular and medical phenotypes.Cell2012
22951037The GENCODE pseudogene resource.Genome Biol2012
22178993Performance comparison of whole-genome sequencing platforms.Nat Biotechnol2011
21307934The genomic complexity of primary human prostate cancer.Nature2011
21036922Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencing.Genome Res2011
21205862Gene inactivation and its implications for annotation in the era of personal genomics.Genes Dev2011
21134889RSEQtools: a modular framework to analyze RNA-Seq data using compact, anonymized data summaries.Bioinformatics2011
20194744Dynamic transcriptomes during neural differentiation of human embryonic stem cells revealed by short, long, and paired-end sequencing.Proc Natl Acad Sci U S A2010
20964841FusionSeq: a modular framework for finding gene fusions by analyzing paired-end RNA-sequencing data.Genome Biol2010
21177976Integrative analysis of the Caenorhabditis elegans genome by the modENCODE project.Science2010
20565764Comparison and calibration of transcriptome data from RNA-Seq and tiling arrays.BMC Genomics2010
20299548Variation in transcription factor binding among humans.Science2010
17437137Rational proteomics of PKD1. I. Modeling the three dimensional structure and ligand specificity of the C_lectin binding domain of Polycystin-1.J Mol Model2007
16245321Rational genomics I: antisense open reading frames and codon bias in short-chain oxido reductase enzymes and the evolution of the genetic code.Proteins2005
16467263Determining structure and function of steroid dehydrogenase enzymes by sequence analysis, homology modeling, and rational mutational analysis.Ann N Y Acad Sci2005
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