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Author Details

Ann Marshak-Rothstein
University of Massachusetts School of Medicine
1976
192
63
PMIDPaper TitleJournal TitlePublished Year
36638547Type-1 interferon-dependent and -independent mechanisms in cyclic GMP-AMP synthase-stimulator of interferon genes-driven auto-inflammation.Curr Opin Immunol2023
37714151Antigen receptor signaling and cell death resistance controls intestinal humoral response zonation.Immunity2023
37555846Disease in the Pld4thss/thss Model of Murine Lupus Requires TLR9.Immunohorizons2023
37547024Expression of a STING Gain-of-function Mutation in Endothelial Cells Initiates Lymphocytic Infiltration of the Lungs.bioRxiv2023
37546720Activation of Autoreactive Lymphocytes in the Lung by STING Gain-of-function Mutation Radioresistant Cells.bioRxiv2023
37773045TLR9 ligand sequestration by chemokine CXCL4 negatively affects central B cell tolerance.J Exp Med2023
36056604IgD<sup>+</sup> age-associated B cells are the progenitors of the main T-independent B cell response to infection that generates protective Ab and can be induced by an inactivated vaccine in the aged.Aging Cell2022
35833127Th2 to Th1 Transition Is Required for Induction of Skin Lesions in an Inducible and Recurrent Murine Model of Cutaneous Lupus-Like Inflammation.Front Immunol2022
35696583Radioresistant cells initiate lymphocyte-dependent lung inflammation and IFNγ-dependent mortality in STING gain-of-function mice.Proc Natl Acad Sci U S A2022
34051146Dysbiosis exacerbates colitis by promoting ubiquitination and accumulation of the innate immune adaptor STING in myeloid cells.Immunity2021
33854495cGAS-STING Pathway Does Not Promote Autoimmunity in Murine Models of SLE.Front Immunol2021
33565149The FasLane to ocular pathology-metalloproteinase cleavage of membrane-bound FasL determines FasL function.J Leukoc Biol2021
34618691Human nasal wash RNA-Seq reveals distinct cell-specific innate immune responses in influenza versus SARS-CoV-2.JCI Insight2021
31464028Role of Interferon-γ-Producing Th1 Cells in a Murine Model of Type I Interferon-Independent Autoinflammation Resulting From DNase II Deficiency.Arthritis Rheumatol2020
32286184Interplay of Cyclic GMP-AMP Synthase/Stimulator of IFN Genes and Toll-Like Receptor Nucleic Acid Sensing Pathways in Autoinflammation and Abnormal Bone Formation due to DNaseII-Deficiency.Viral Immunol2020
30365944Soluble Fas ligand blocks destructive corneal inflammation in mouse models of corneal epithelial debridement and LPS induced keratitis.Exp Eye Res2019
30243657Advances in Cutaneous Lupus Erythematosus and Dermatomyositis: A Report from the 4th International Conference on Cutaneous Lupus Erythematosus-An Ongoing Need for International Consensus and Collaborations.J Invest Dermatol2019
31534009Cross-Reactive Antigen Expressed by B6 Splenocytes Drives Receptor Editing and Marginal Zone Differentiation of IgG2a-Reactive AM14 Vκ8 B Cells.J Immunol2019
31570110A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma.J Neuroinflammation2019
31569013The role of nucleic acid sensors and type I IFNs in patient populations and animal models of autoinflammation.Curr Opin Immunol2019
31446338Molecular pattern recognition in peripheral B cell tolerance: lessons from age-associated B cells.Curr Opin Immunol2019
30944222Hierarchy of clinical manifestations in SAVI N153S and V154M mouse models.Proc Natl Acad Sci U S A2019
29212904Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.J Immunol2018
29889098Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation.J Clin Invest2018
29768176The Chaperone UNC93B1 Regulates Toll-like Receptor Stability Independently of Endosomal TLR Transport.Immunity2018
29531167Correction: Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.J Immunol2018
27531928Taking the STING out of TLR-driven autoimmune diseases: good, bad, or indifferent?J Leukoc Biol2017
28346226A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens.J Clin Invest2017
28239656Autoreactive helper T cells alleviate the need for intrinsic TLR signaling in autoreactive B cell activation.JCI Insight2017
27740718STING Contributes to Abnormal Bone Formation Induced by Deficiency of DNase II in Mice.Arthritis Rheumatol2017
26729810Synergy between Hematopoietic and Radioresistant Stromal Cells Is Required for Autoimmune Manifestations of DNase II-/-IFNaR-/- Mice.J Immunol2016
27849168Overexpression of Soluble Fas Ligand following Adeno-Associated Virus Gene Therapy Prevents Retinal Ganglion Cell Death in Chronic and Acute Murine Models of Glaucoma.J Immunol2016
27354219TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus.J Immunol2016
26803634Toll-Like Receptor-Dependent Immune Complex Activation of B Cells and Dendritic Cells.Methods Mol Biol2016
26683141Autoimmunity--promoting and stabilizing innate immunity 'UNWUCHT'.Immunol Rev2016
24914072Gadolinium-based compounds induce NLRP3-dependent IL-1β production and peritoneal inflammation.Ann Rheum Dis2015
26432899Nucleic Acid-Sensing Receptors: Rheostats of Autoimmunity and Autoinflammation.J Immunol2015
26457825An unexpected role for RNA-sensing toll-like receptors in a murine model of DNA accrual.Clin Exp Rheumatol2015
26583327Membrane-bound and soluble Fas ligands have opposite functions in photoreceptor cell death following separation from the retinal pigment epithelium.Cell Death Dis2015
26519529IL-21 Promotes Pulmonary Fibrosis through the Induction of Profibrotic CD8+ T Cells.J Immunol2015
25681333Cell-intrinsic expression of TLR9 in autoreactive B cells constrains BCR/TLR7-dependent responses.J Immunol2015
25646421Suppression of systemic autoimmunity by the innate immune adaptor STING.Proc Natl Acad Sci U S A2015
25601924Cutting Edge: DNase II deficiency prevents activation of autoreactive B cells by double-stranded DNA endogenous ligands.J Immunol2015
25548216Cutting edge: AIM2 and endosomal TLRs differentially regulate arthritis and autoantibody production in DNase II-deficient mice.J Immunol2015
24442443Cutting edge: Self-antigen controls the balance between effector and regulatory T cells in peripheral tissues.J Immunol2014
25187660Cutting edge: the UNC93B1 tyrosine-based motif regulates trafficking and TLR responses via separate mechanisms.J Immunol2014
24952505The adaptor ASC has extracellular and 'prionoid' activities that propagate inflammation.Nat Immunol2014
23291967Phenotype and function of B cells and dendritic cells from interferon regulatory factor 5-deficient mice with and without a mutation in DOCK2.Int Immunol2013
24246387Organ-specific and systemic autoimmune diseases.Curr Opin Immunol2013
23918976Overexpression of membrane-bound fas ligand (CD95L) exacerbates autoimmune disease and renal pathology in pristane-induced lupus.J Immunol2013
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Collaborators

Katherine A Fitzgerald
Co-authored papers 20
Melissa B Uccellini
Icahn School of Medicine at Mount Sinaigrid.59734.3c
Co-authored papers 8
Drew Weissman
Co-authored papers 3
Frances E Lund
The University of Alabama at Birmingham
Co-authored papers 3
Timothy R D J Radstake
Co-authored papers 2
Michael Dean
National Cancer Institute
Co-authored papers 2
Quan-Zhen Li
Co-authored papers 2
Paul J Utz
Co-authored papers 2
Stephen P Jackson
Mission Therapeutics Ltd. Glenn Berge Building
Co-authored papers 1
E Clayton
Harvard Medical School, Vanderbilt University, Yale University Yale Law School
Co-authored papers 1
Scott A Shaffer
Co-authored papers 1
William J Kaiser
University of California Los Angeles
Co-authored papers 1
Jason W Bauer
Co-authored papers 1
Nir Hacohen
Broad Institute of MIT and Harvard
Co-authored papers 1
Richard A Miller
University of Michigan School of Medicine ann arbor
Co-authored papers 1
Laura F Mahon
Co-authored papers 1
Noel N Kim
Co-authored papers 1
Kristine Coughlin
Frontier Science and Technology Research Foundation
Co-authored papers 1
Jo Anne Bennett
New York University
Co-authored papers 1
Timothy W Behrens
Genentech Inc.
Co-authored papers 1
Rajesh T Gandhi
Co-authored papers 1
Daniel R Kuritzkes
Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 1
Jeffrey M Jacobson
Co-authored papers 1
Neal Silverman
Co-authored papers 1
Douglas D Richman
Center for AIDS Research, University of California San Diego
Co-authored papers 1
Steven M Greenberg
Massachusetts General Hospital
Co-authored papers 1
Margaret A Matula
Co-authored papers 1
Paul Kussie
Co-authored papers 1
Jody Lawrence
Inc., Collegeville
Co-authored papers 1
Cara Sutcliffe
Vanderbilt University
Co-authored papers 1
Release 1.2