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Author Details
Full Name
Samuel B Luty
Affiliation
Knight Cancer Institute, Oregon Health & Science University
ORCID
Career Start Year
2011
Papers
13
H Index
12
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
35868306
Integrative analysis of drug response and clinical outcome in acute myeloid leukemia.
Cancer Cell
2022
30333627
Functional genomic landscape of acute myeloid leukaemia.
Nature
2018
30018082
Synthetic lethality of TNK2 inhibition in PTPN11-mutant leukemia.
Sci Signal
2018
29132397
Kinase profiling of liposarcomas using RNAi and drug screening assays identified druggable targets.
J Hematol Oncol
2017
28439110
Characterization of the leukemogenic potential of distal cytoplasmic CSF3R truncation and missense mutations.
Leukemia
2017
26677978
Identification and Characterization of Tyrosine Kinase Nonreceptor 2 Mutations in Leukemia through Integration of Kinase Inhibitor Screening and Genomic Analysis.
Cancer Res
2016
26458983
JAK2(V617I) results in cytokine hypersensitivity without causing an overt myeloproliferative disorder in a mouse transduction-transplantation model.
Exp Hematol
2016
26475333
The Colony-Stimulating Factor 3 Receptor T640N Mutation Is Oncogenic, Sensitive to JAK Inhibition, and Mimics T618I.
Clin Cancer Res
2016
26032424
Therapeutically Targetable ALK Mutations in Leukemia.
Cancer Res
2015
24403076
Ligand independence of the T618I mutation in the colony-stimulating factor 3 receptor (CSF3R) protein results from loss of O-linked glycosylation and increased receptor dimerization.
J Biol Chem
2014
24081659
The CSF3R T618I mutation causes a lethal neutrophilic neoplasia in mice that is responsive to therapeutic JAK inhibition.
Blood
2013
22889761
Effects of plerixafor in combination with BCR-ABL kinase inhibition in a murine model of CML.
Blood
2012
21860020
TNFα facilitates clonal expansion of JAK2V617F positive cells in myeloproliferative neoplasms.
Blood
2011
1 - 13 of 13
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Angela Rofelty
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