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Author Details

Gregory M Barton
University of California berkeley
1998
61
39
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37337046A genetic system for Akkermansia muciniphila reveals a role for mucin foraging in gut colonization and host sterol biosynthesis gene expression.Nat Microbiol2023
34272507Regulation of the nucleic acid-sensing Toll-like receptors.Nat Rev Immunol2022
34006653Genotypic and Phenotypic Diversity among Human Isolates of Akkermansia muciniphila.mBio2021
33531682Toll-like receptors form different complexes with UNC93B1.Nat Struct Mol Biol2021
34863507Editorial overview: Communities in immune cell signaling.Curr Opin Immunol2021
31980536Dysregulation of TLR9 in neonates leads to fatal inflammatory disease driven by IFN-γ.Proc Natl Acad Sci U S A2020
31221858<i>Akkermansia muciniphila</i> induces intestinal adaptive immune responses during homeostasis.Science2019
31433298B cell receptor and Toll-like receptor signaling coordinate to control distinct B-1 responses to both self and the microbiota.Elife2019
31204998Cas9<sup>+</sup> conditionally-immortalized macrophages as a tool for bacterial pathogenesis and beyond.Elife2019
31546247Release from UNC93B1 reinforces the compartmentalized activation of select TLRs.Nature2019
31546246UNC93B1 recruits syntenin-1 to dampen TLR7 signalling and prevent autoimmunity.Nature2019
31631836Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis.Elife2019
30170812A Map of Toll-like Receptor Expression in the Intestinal Epithelium Reveals Distinct Spatial, Cell Type-Specific, and Temporal Patterns.Immunity2018
27907816Nucleic acid-sensing TLRs: trafficking and regulation.Curr Opin Immunol2017
28219890Local TNFR1 Signaling Licenses Murine Neutrophils for Increased TLR-Dependent Cytokine and Eicosanoid Production.J Immunol2017
29150239Tissue-Resident Macrophages Are Locally Programmed for Silent Clearance of Apoptotic Cells.Immunity2017
26903634Differences in codon bias and GC content contribute to the balanced expression of TLR7 and TLR9.Proc Natl Acad Sci U S A2016
27153495Maternal IgG and IgA Antibodies Dampen Mucosal T Helper Cell Responses in Early Life.Cell2016
24439965Trafficking of endosomal Toll-like receptors.Trends Cell Biol2014
25580251MyD88: a central player in innate immune signaling.F1000Prime Rep2014
25395297Emerging principles governing signal transduction by pattern-recognition receptors.Cold Spring Harb Perspect Biol2014
25155465Internalization and TLR-dependent type I interferon production by monocytes in response to Toxoplasma gondii.Immunol Cell Biol2014
24528866Toll-like receptor-deficient mice reveal how innate immune signaling influences Salmonella virulence strategies.Cell Host Microbe2014
23290772The impact of Toll-like receptors on bacterial virulence strategies.Curr Opin Microbiol2013
24145778No antigen-presentation defect in Unc93b1(3d/3d) (3d) mice.Nat Immunol2013
24237694TLR5 stops commensals in their tracks.Cell Host Microbe2013
23426999UNC93B1 mediates differential trafficking of endosomal TLRs.Elife2013
22423970Cofactors required for TLR7- and TLR9-dependent innate immune responses.Cell Host Microbe2012
21219183Nucleic acid recognition by the innate immune system.Annu Rev Immunol2011
22440908Toll-like receptors: key players in antiviral immunity.Curr Opin Virol2011
22078883CD14 controls the LPS-induced endocytosis of Toll-like receptor 4.Cell2011
22078797Transmembrane mutations in Toll-like receptor 9 bypass the requirement for ectodomain proteolysis and induce fatal inflammation.Immunity2011
21666062Suppression of TLR9 immunostimulatory motifs in the genome of a gammaherpesvirus.J Immunol2011
21376231TLR signaling is required for Salmonella typhimurium virulence.Cell2011
21402738Nucleic acid recognition by Toll-like receptors is coupled to stepwise processing by cathepsins and asparagine endopeptidase.J Exp Med2011
21146971Nucleic acid sensing Toll-like receptors in autoimmunity.Curr Opin Immunol2011
20404847Unfolding new roles for XBP1 in immunity.Nat Immunol2010
21119105Compartment-specific control of signaling from a DNA-sensing immune receptor.Sci Signal2010
20951963MicroRNAs and LPS: developing a relationship in the neonatal gut.Cell Host Microbe2010
19556980A cell biological view of Toll-like receptor function: regulation through compartmentalization.Nat Rev Immunol2009
19801985Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands.Nat Immunol2009
18300366A mechanism for the initiation of allergen-induced T helper type 2 responses.Nat Immunol2008
18820679The ectodomain of Toll-like receptor 9 is cleaved to generate a functional receptor.Nature2008
18246191A calculated response: control of inflammation by the innate immune system.J Clin Invest2008
17336545Viral recognition by Toll-like receptors.Semin Immunol2007
16341217Intracellular localization of Toll-like receptor 9 prevents recognition of self DNA but facilitates access to viral DNA.Nat Immunol2006
15116112Toll signaling: RIPping off the TNF pathway.Nat Immunol2004
12791976Toll-like receptor signaling pathways.Science2003
12719735Linking Toll-like receptors to IFN-alpha/beta expression.Nat Immunol2003
12011451Positive selection of self-MHC-reactive T cells by individual peptide-MHC class II complexes.Proc Natl Acad Sci U S A2002
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Collaborators

Henan University
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University of California berkeley
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University of California berkeley
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Duke University
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Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
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University of California berkeley
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
University of California berkeley
Co-authored papers 1
Prestige BioPharma Ltd
Co-authored papers 1
university of california san diego School of Medicine
Co-authored papers 1
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Broad Institute of MIT and Harvard
Co-authored papers 1
United States Army Medical Research Institute of Infectious Diseases
Co-authored papers 1
Sanford-Burnham Medical Research Institute
Co-authored papers 1
University of California irvine
Co-authored papers 1
University of California Berkeley
Co-authored papers 1
Fred Hutchinson Cancer Research Center
Co-authored papers 1
National Institute of Allergy and Infectious Diseases
Co-authored papers 1
Icahn School of Medicine at Mount Sinai
Co-authored papers 1
Genomics Institute of the Novartis Research Foundation
Co-authored papers 1
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University of California berkeley
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University of California berkeley
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The Scripps Research Institute
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