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Author Details

Leah C Kottyan
Cincinnati Children's Hospital Medical Center
2009
93
28
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36383166Utilization of electronic health record data to evaluate the association of urban environment with systemic lupus erythematosus symptoms.Rheumatology (Oxford)2023
37758692Proteomic and genetic analyses of influenza A viruses identify pan-viral host targets.Nat Commun2023
37660987Breakthroughs in understanding and treating eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERs Symposium at the 2022 American Academy of Allergy, Asthma & Immunology Meeting.J Allergy Clin Immunol2023
37794597Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells.Cell Rep2023
37745430After the Infection: A Survey of Pathogens and Non-communicable Human Disease.medRxiv2023
37455310A functional mechanism for a non-coding variant near AGTR2 associated with risk for preterm birth.BMC Med2023
36949074A DNA tumor virus globally reprograms host 3D genome architecture to achieve immortal growth.Nat Commun2023
36945549An atlas of gene regulatory networks for memory CD4 <sup>+</sup> T cells in youth and old age.bioRxiv2023
37337107Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy.Nat Genet2023
36621880Returning integrated genomic risk and clinical recommendations: The eMERGE study.Genet Med2023
36719906maxATAC: Genome-scale transcription-factor binding prediction from ATAC-seq with deep neural networks.PLoS Comput Biol2023
36585519Gene-environment interactions and their impact on human health.Genes Immun2023
36400179Genome-wide admixture and association analysis identifies African ancestry-specific risk loci of eosinophilic esophagitis in African Americans.J Allergy Clin Immunol2023
36846987Inference of Causal Relationships Between Genetic Risk Factors for Cardiometabolic Phenotypes and Female-Specific Health Conditions.J Am Heart Assoc2023
36746961Author Correction: Genetic regulation of serum IgA levels and susceptibility to common immune, infectious, kidney, and cardio-metabolic traits.Nat Commun2023
36778284B cell repertoire in children with skin barrier dysfunction supports altered IgE maturation associated with allergic food sensitization.bioRxiv2023
36540998Quantifying factors that affect polygenic risk score performance across diverse ancestries and age groups for body mass index.Pac Symp Biocomput2023
36824978Macrophage epigenetic memories of early life injury drive neonatal nociceptive priming.bioRxiv2023
35252945CASCADE: high-throughput characterization of regulatory complex binding altered by non-coding variants.Cell Genom2022
35765100Development and validation of a trans-ancestry polygenic risk score for type 2 diabetes in diverse populations.Genome Med2022
35576187Epigenetic and transcriptional dysregulation in CD4+ T cells in patients with atopic dermatitis.PLoS Genet2022
35595084Multiancestral polygenic risk score for pediatric asthma.J Allergy Clin Immunol2022
35388006Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery.Nat Commun2022
36253972Frontotemporal degeneration genetic risk loci and transcription regulation as a possible mechanistic link to disease risk.Medicine (Baltimore)2022
36376295Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure.Nat Commun2022
33446329Very early onset eosinophilic esophagitis is common, responds to standard therapy, and demonstrates enrichment for CAPN14 genetic variants.J Allergy Clin Immunol2021
33712590Global discovery of lupus genetic risk variant allelic enhancer activity.Nat Commun2021
33761354IRF1 governs the differential interferon-stimulated gene responses in human monocytes and macrophages by regulating chromatin accessibility.Cell Rep2021
34473385Whole blood transcriptomics identifies gene expression associated with peanut allergy in infants at high risk.Clin Exp Allergy2021
34815391Desmoplakin and periplakin genetically and functionally contribute to eosinophilic esophagitis.Nat Commun2021
34799401Epstein-Barr virus nuclear antigen 2 extensively rewires the human chromatin landscape at autoimmune risk loci.Genome Res2021
33941608Medical Records-Based Genetic Studies of the Complement System.J Am Soc Nephrol2021
34176557Epigenetics of obstructive sleep apnea syndrome: a systematic review.J Clin Sleep Med2021
34111109Runx1 shapes the chromatin landscape via a cascade of direct and indirect targets.PLoS Genet2021
33272962Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus.Ann Rheum Dis2021
33446330Replication and meta-analyses nominate numerous eosinophilic esophagitis risk genes.J Allergy Clin Immunol2021
32375053Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming.Cell Rep2020
32017227IL-33 promotes type 1 cytokine expression via p38 MAPK in human NK cells.J Leukoc Biol2020
31980060Noncoding Variants as Genetic Contributors to Autoimmune Disease Pathogenesis.J Invest Dermatol2020
31910986The genetic etiology of eosinophilic esophagitis.J Allergy Clin Immunol2020
33426398Comprehensive Review of Steroid-Sensitive Nephrotic Syndrome Genetic Risk Loci and Transcriptional Regulation as a Possible Mechanistic Link to Disease Risk.Kidney Int Rep2020
33205070Erratum: Therapeutic Targeting of Follicular T Cells with Chimeric Antigen Receptor-Expressing Natural Killer Cells.Cell Rep Med2020
32864635Therapeutic Targeting of Follicular T Cells with Chimeric Antigen Receptor-Expressing Natural Killer Cells.Cell Rep Med2020
32405233The Promise and Peril of Natural Killer Cell Therapies in Pulmonary Infection.Immunity2020
30414468Immunology of the ancestral differences in eosinophilic esophagitis.Ann Allergy Asthma Immunol2019
29904099Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis.Genes Immun2019
3057887017β-Estradiol protects the esophageal epithelium from IL-13-induced barrier dysfunction and remodeling.J Allergy Clin Immunol2019
30423114Genetic influences on susceptibility to rheumatoid arthritis in African-Americans.Hum Mol Genet2019
30626591Genetic, Inflammatory, and Epithelial Cell Differentiation Factors Control Expression of Human Calpain-14.G3 (Bethesda)2019
29129581Eosinophilic esophagitis (EoE) genetic susceptibility is mediated by synergistic interactions between EoE-specific and general atopic disease loci.J Allergy Clin Immunol2018
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Collaborators

Matthew T Weirauch
University of Cincinnati College of Medicine
Co-authored papers 34
John B Harley
US Department of Veterans Affairs Medical Center
Co-authored papers 28
Marc E Rothenberg
Cincinnati Children's Hospital Medical Center
Co-authored papers 23
Lisa J Martin
Co-authored papers 17
Bahram Namjou
Cincinnati Children's Hospital
Co-authored papers 15
Patrick M Gaffney
Co-authored papers 10
Carl D Langefeld
Wake Forest University School of Medicine
Co-authored papers 9
Joel M Guthridge
Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation
Co-authored papers 8
Kathy L Moser
Co-authored papers 8
Gail P Jarvik
University of Washington Medical Center
Co-authored papers 6
Timothy J Vyse
Co-authored papers 6
Krzysztof Kiryluk
Columbia University
Co-authored papers 6
Barry I Freedman
Co-authored papers 5
Deborah S Cunninghame Graham
Co-authored papers 5
Marylyn D Ritchie
Center for Systems Genomics, Pennsylvania State University, University Park
Co-authored papers 5
Michelle Petri
Co-authored papers 5
Wei-Qi Wei
Vanderbilt University Medical Center
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Gurjit K Khurana Hershey
Cincinnati Children's Hospital Medical Center
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John D Reveille
University of Texas
Co-authored papers 5
Joshua C Denny
Vanderbilt University
Co-authored papers 5
Lindsey A Criswell
Co-authored papers 5
Iftikhar J Kullo
Mayo Clinic
Co-authored papers 5
Elizabeth W Karlson
Brigham and Women's Hospital
Co-authored papers 4
Hakon Hakonarson
The Center for Applied Genomics, Children's Hospital of Philadelphia
Co-authored papers 4
Shefali S Verma
University of Pennsylvania
Co-authored papers 4
David R Crosslin
University of Washington Medical Center
Co-authored papers 4
Hemant K Tiwari
University of Alabama at Birmingham
Co-authored papers 4
David W Fardo
University of Kentucky
Co-authored papers 4
Brad G Kurowski
Cincinnati Children's Hospital Medical Center
Co-authored papers 4
Theresa L Walunas
Northwestern University Feinberg School of Medicine
Co-authored papers 4
Release 1.2