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Author Details

Wendy Sandoval
Genentech Inc.
2006
81
33
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37161726Activation of the PERK branch of the unfolded protein response during production reduces specific productivity in CHO cells via downregulation of PDGFRa and IRE1a signaling.Biotechnol Prog2023
37478487UniDec Processing Pipeline for Rapid Analysis of Biotherapeutic Mass Spectrometry Data.Anal Chem2023
36099298Deletion of a previously uncharacterized lipoprotein lirL confers resistance to an inhibitor of type II signal peptidase in <i>Acinetobacter baumannii</i>.Proc Natl Acad Sci U S A2022
35611591Stress-induced vesicular assemblies of dual leucine zipper kinase are signaling hubs involved in kinase activation and neurodegeneration.EMBO J2022
35361882BMP1 is not required for lung fibrosis in mice.Sci Rep2022
33472215NINJ1 mediates plasma membrane rupture during lytic cell death.Nature2021
33682619Fc galactosylation follows consecutive reaction kinetics and enhances immunoglobulin G hexamerization for complement activation.MAbs2021
33713388The lysosomal endopeptidases Cathepsin D and L are selective and effective proteases for the middle-down characterization of antibodies.FEBS J2021
33903764Gremlin 1<sup>+</sup> fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues.Nat Immunol2021
33875545Inhibition of Escherichia coli Lipoprotein Diacylglyceryl Transferase Is Insensitive to Resistance Caused by Deletion of Braun's Lipoprotein.J Bacteriol2021
33754705Serum Lysophosphatidic Acid Measurement by Liquid Chromatography-Mass Spectrometry in COPD Patients.J Am Soc Mass Spectrom2021
33727605Ocular phenotypes in a mouse model of impaired glucocerebrosidase activity.Sci Rep2021
33886297Denaturing and Native Mass Spectrometric Analytics for Biotherapeutic Drug Discovery Research: Historical, Current, and Future Personal Perspectives.J Am Soc Mass Spectrom2021
34556083Lysophosphatidic acid species are associated with exacerbation in chronic obstructive pulmonary disease.BMC Pulm Med2021
34344156Editorial: Special JASMS Focus on Mass Spectrometry in Industry.J Am Soc Mass Spectrom2021
34288605Preventing pyruvate kinase muscle expression in Chinese hamster ovary cells curbs lactogenic behavior by altering glycolysis, gating pyruvate generation, and increasing pyruvate flux into the TCA cycle.Biotechnol Prog2021
32558906UBR E3 ligases and the PDIA3 protease control degradation of unfolded antibody heavy chain by ERAD.J Cell Biol2020
31846224Endothelial intercellular cell adhesion molecule 1 contributes to cell aggregate formation in CHO cells cultured in serum-free media.Biotechnol Prog2020
32788728Structure of the essential inner membrane lipopolysaccharide-PbgA complex.Nature2020
32812765Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry.J Am Soc Mass Spectrom2020
32274410Data on charge separation of bispecific and mispaired IgGs using native charge-variant mass spectrometry.Data Brief2020
30444371In Vivo Stability Profiles of Anti-factor D Molecules Support Long-Acting Delivery Approaches.Mol Pharm2019
31747256Native Hydrophobic Interaction Chromatography Hyphenated to Mass Spectrometry for Characterization of Monoclonal Antibody Minor Variants.Anal Chem2019
30179303Pyruvate Kinase Muscle-1 Expression Appears to Drive Lactogenic Behavior in CHO Cell Lines, Triggering Lower Viability and Productivity: A Case Study.Biotechnol J2019
31578523The RIPK4-IRF6 signalling axis safeguards epidermal differentiation and barrier function.Nature2019
31371506Disruption of IRE1α through its kinase domain attenuates multiple myeloma.Proc Natl Acad Sci U S A2019
31286843Elucidating heavy/light chain pairing preferences to facilitate the assembly of bispecific IgG in single cells.MAbs2019
31231034A Stromal Niche Defined by Expression of the Transcription Factor WT1 Mediates Programming and Homeostasis of Cavity-Resident Macrophages.Immunity2019
31251757Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye.PLoS One2019
31534238Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.Nat Immunol2019
30778250Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth.Nat Immunol2019
31122132Production, characterization, and <i>in vivo</i> half-life extension of polymeric IgA molecules in mice.MAbs2019
30824837Therapeutic resistance and susceptibility is shaped by cooperative multi-compartment tumor adaptation.Cell Death Differ2019
30525646Discovery and Qualification of Candidate Urinary Biomarkers of Disease Activity in Lupus Nephritis.J Proteome Res2019
30597531Interaction of cell culture process parameters for modulating mAb afucosylation.Biotechnol Bioeng2019
30481450Quantitative Determination of Protein-Ligand Affinity by Size Exclusion Chromatography Directly Coupled to High-Resolution Native Mass Spectrometry.Anal Chem2019
30307368High-resolution glycosylation site-engineering method identifies MICA epitope critical for shedding inhibition activity of anti-MICA antibodies.MAbs2019
28986978Comparison of platform host cell protein ELISA to process-specific host cell protein ELISA.Biotechnol Bioeng2018
30043751Pan-Cancer Metabolic Signature Predicts Co-Dependency on Glutaminase and De Novo Glutathione Synthesis Linked to a High-Mesenchymal Cell State.Cell Metab2018
30118681Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate.Mol Cell2018
30339478Charge variant native mass spectrometry benefits mass precision and dynamic range of monoclonal antibody intact mass analysis.MAbs2018
29443976How many human proteoforms are there?Nat Chem Biol2018
29798909Tumor Elastography and Its Association with Collagen and the Tumor Microenvironment.Clin Cancer Res2018
27779884De Novo MS/MS Sequencing of Native Human Antibodies.J Proteome Res2017
29129068Structural and Functional Characterization of a Hole-Hole Homodimer Variant in a "Knob-Into-Hole" Bispecific Antibody.Anal Chem2017
28511073Preparation and evaluation of L- and D-5-[<sup>18</sup>F]fluorotryptophan as PET imaging probes for indoleamine and tryptophan 2,3-dioxygenases.Nucl Med Biol2017
28536290Peptidoglycan Association of Murein Lipoprotein Is Required for KpsD-Dependent Group 2 Capsular Polysaccharide Expression and Serum Resistance in a Uropathogenic <i>Escherichia coli</i> Isolate.mBio2017
28801535Expansion of the ISWI chromatin remodeler family with new active complexes.EMBO Rep2017
27929752Efficient production of bispecific IgG of different isotypes and species of origin in single mammalian cells.MAbs2017
26724994Palmitoylation of TEAD Transcription Factors Is Required for Their Stability and Function in Hippo Pathway Signaling.Structure2016
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Release 1.2