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Author Details

David Cowburn
Albert Einstein College of Medicine
1969
151
46
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37064528Improving the Hole Picture: Towards a Consensus on the Mechanism of Nuclear Transport.ArXiv2023
37099395Improving the hole picture: towards a consensus on the mechanism of nuclear transport.Biochem Soc Trans2023
35231399Resurfaced ZIKV EDIII nanoparticle immunogens elicit neutralizing and protective responses in vivo.Cell Chem Biol2022
35679349A Powassan virus domain III nanoparticle immunogen elicits neutralizing and protective antibodies in mice.PLoS Pathog2022
35528138NMR Assignment through Linear Programming.J Glob Optim2022
36194550A Conserved Histidine Residue Drives Extein Dependence in an Enhanced Atypically Split Intein.J Am Chem Soc2022
33980829INI1/SMARCB1 Rpt1 domain mimics TAR RNA in binding to integrase to facilitate HIV-1 replication.Nat Commun2021
32696372Analysis of Multivalent IDP Interactions: Stoichiometry, Affinity, and Local Concentration Effect Measurements.Methods Mol Biol2020
31199001Phase separation in biology and disease-a symposium report.Ann N Y Acad Sci2019
29429880Deciphering the "Fuzzy" Interaction of FG Nucleoporins and Transport Factors Using Small-Angle Neutron Scattering.Structure2018
30156841An Atypical Mechanism of Split Intein Molecular Recognition and Folding.J Am Chem Soc2018
29374059Thermodynamic characterization of the multivalent interactions underlying rapid and selective translocation through the nuclear pore complex.J Biol Chem2018
27714614Segmental Isotopic Labeling of Proteins for NMR Study Using Intein Technology.Methods Mol Biol2017
28162953Molecular Architecture of the Major Membrane Ring Component of the Nuclear Pore Complex.Structure2017
28151998Effects of FGFR2 kinase activation loop dynamics on catalytic activity.PLoS Comput Biol2017
29263320Dynamic intramolecular regulation of the histone chaperone nucleoplasmin controls histone binding and release.Nat Commun2017
28616711Integrating NOE and RDC using sum-of-squares relaxation for protein structure determination.J Biomol NMR2017
28739907A promiscuous split intein with expanded protein engineering applications.Proc Natl Acad Sci U S A2017
27815825Domain interactions of C-terminal Src Kinase determined through NMR spectroscopy with segmental isotope labeling.Protein Cell2017
26854538Design of a Split Intein with Exceptional Protein Splicing Activity.J Am Chem Soc2016
26655427Anti-DNA antibody mediated catalysis is isotype dependent.Mol Immunol2016
26482679A peptide mimic blocks the cross-reaction of anti-DNA antibodies with glomerular antigens.Clin Exp Immunol2016
27819029Combining biophysical methods to analyze the disulfide bond in SH2 domain of C-terminal Src kinase.Biophys Rep2016
27091992Slide-and-exchange mechanism for rapid and selective transport through the nuclear pore complex.Proc Natl Acad Sci U S A2016
25749870Erratum to: Correlation of chemical shifts predicted by molecular dynamics simulations for partially disordered proteins.J Biomol NMR2015
26371551The molecular mechanism of nuclear transport revealed by atomic-scale measurements.Elife2015
26690112Identification of Hydrophobic Interfaces in Protein-Ligand Complexes by Selective Saturation Transfer NMR Spectroscopy.Molecules2015
25634639Controlling lipid micelle stability using oligonucleotide headgroups.J Am Chem Soc2015
24695731Structural and dynamical features of inteins and implications on protein splicing.J Biol Chem2014
23506399Extein residues play an intimate role in the rate-limiting step of protein trans-splicing.J Am Chem Soc2013
24236406Naturally split inteins assemble through a "capture and collapse" mechanism.J Am Chem Soc2013
23911417Global structures of IgG isotypes expressing identical variable regions.Mol Immunol2013
23871672Cracking the molecular origin of intrinsic tyrosine kinase activity through analysis of pathogenic gain-of-function mutations.Cell Rep2013
23583913Ligand-induced dynamic changes in extended PDZ domains from NHERF1.J Mol Biol2013
22167671Expression and purification of Src-family kinases for solution NMR studies.Methods Mol Biol2012
24432187Eigenvector synchronization, graph rigidity and the molecule problem.Inf inference2012
22930758Variable region identical immunoglobulins differing in isotype express different paratopes.J Biol Chem2012
22592215Abl kinase constructs expressed in bacteria: facilitation of structural and functional studies including segmental labeling by expressed protein ligation.Mol Biosyst2012
22244757The alternatively spliced acid box region plays a key role in FGF receptor autoinhibition.Structure2012
22170623Novel structures of self-associating stapled peptides.Biopolymers2012
21067413Are zinc-finger domains of protein kinase C dynamic structures that unfold by lipid or redox activation?Antioxid Redox Signal2011
21539734Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain.Retrovirology2011
20042604A conformational switch in the scaffolding protein NHERF1 controls autoinhibition and complex formation.J Biol Chem2010
20880835Local control of a disorder-order transition in 4E-BP1 underpins regulation of translation via eIF4E.Proc Natl Acad Sci U S A2010
20951618On the measurement of ¹⁵N-{¹H} nuclear Overhauser effects. 2. Effects of the saturation scheme and water signal suppression.J Magn Reson2010
20495572Branched intermediate formation stimulates peptide bond cleavage in protein splicing.Nat Chem Biol2010
20633361Nuclear spin relaxation in isotropic and anisotropic media.Prog Nucl Magn Reson Spectrosc2010
20372977Structural determination of biomolecular interfaces by nuclear magnetic resonance of proteins with reduced proton density.J Biomol NMR2010
19358609Accurate sampling of high-frequency motions in proteins by steady-state (15)N-{(1)H} nuclear Overhauser effect measurements in the presence of cross-correlated relaxation.J Am Chem Soc2009
19632474Segmental isotopic labeling of proteins for nuclear magnetic resonance.Methods Enzymol2009
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Collaborators

Princeton University
Co-authored papers 17
University of Maryland, College Park
Co-authored papers 15
Guru Nanak Institute of Dental Sciences and Research
Co-authored papers 15
The Fenway Institute
Co-authored papers 12
Molecular Biology Institute, University of California los angeles
Co-authored papers 11
The Rockefeller University
Co-authored papers 8
Albert Einstein College of Medicine
Co-authored papers 7
University of California berkeley
Co-authored papers 6
New York University (NYU) Langone Health
Co-authored papers 5
Rockefeller University
Co-authored papers 4
University of Alberta
Co-authored papers 4
University of California San Francisco
Co-authored papers 3
Co-authored papers 3
University of Utah
Co-authored papers 3
Institute of Molecular Medicine, Martin-Luther-University of Halle-Wittenberg
Co-authored papers 3
Albert Einstein College of Medicine
Co-authored papers 2
Albert Einstein College of Medicine
Co-authored papers 2
Albert Einstein College of Medicine
Co-authored papers 2
The Rockefeller University
Co-authored papers 2
Washington University School of Medicine
Co-authored papers 2
Johns Hopkins Bloomberg School of Public Health
Co-authored papers 2
Stanford University
Co-authored papers 1
Neuroscience Institute, NYU Grossman School of Medicine
Co-authored papers 1
Dalton Cardiovascular Research Center, University of Missouri
Co-authored papers 1
Co-authored papers 1
Institute for Advanced Study, Technical University Munich
Co-authored papers 1
Albert Einstein College of Medicine
Co-authored papers 1
Co-authored papers 1
Leibniz-Forschungsinstitut fur Molekulare Pharmakologie
Co-authored papers 1
Gwangju Institute of Science and Technology
Co-authored papers 1