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Author Details

John C Crabbe
Portland Alcohol Research Center, Oregon Health & Science University
1972
375
72
PMIDPaper TitleJournal TitlePublished Year
36656645Preclinical and clinical evidence for suppression of alcohol intake by apremilast.J Clin Invest2023
37503148DISCOVERY AND VALIDATION OF GENES DRIVING DRUG-INTAKE AND RELATED BEHAVIORAL TRAITS IN MICE.bioRxiv2023
34227188Long-term alcohol drinking in High Drinking in the Dark mice is stable for many months and does not show alcohol deprivation effects.Addict Biol2022
35645743Corticosterone Levels and Glucocorticoid Receptor Gene Expression in High Drinking in the Dark Mice and Their Heterogeneous Stock (HS/NPT) Founder Line.Front Behav Neurosci2022
36001437Midazolam, methamphetamine, morphine and nicotine intake in high-drinking-in-the-dark mice.Addict Biol2022
36198764Genetic and genomic signatures in ethanol withdrawal seizure-prone and seizure-resistant mice implicate genes involved in epilepsy and neuronal excitability.Mol Psychiatry2022
33556460The impact of Drinking in the Dark (DID) procedural manipulations on ethanol intake in High Drinking in the Dark (HDID) mice.Alcohol2021
33557285Ethanol-Related Behaviors in Mouse Lines Selectively Bred for Drinking to Intoxication.Brain Sci2021
31175946Suppression of voluntary ethanol intake in mice under constant light and constant darkness.Alcohol2020
34589846Tetracycline derivatives reduce binge alcohol consumption in High Drinking in the Dark mice.Brain Behav Immun Health2020
31853996Effects of Pharmacologically Targeting Neuroimmune Pathways on Alcohol Drinking in Mice Selectively Bred to Drink to Intoxication.Alcohol Clin Exp Res2020
33294845Effects of Tacrolimus and Other Immune Targeting Compounds on Binge-Like Ethanol Drinking in High Drinking in the Dark Mice.Neurosci Insights2020
32154593Targeting the Glucocorticoid Receptor Reduces Binge-Like Drinking in High Drinking in the Dark (HDID-1) Mice.Alcohol Clin Exp Res2020
30609665Ethanol Conditioned Taste Aversion in High Drinking in the Dark Mice.Brain Sci2019
30062672Dissecting Brain Networks Underlying Alcohol Binge Drinking Using a Systems Genomics Approach.Mol Neurobiol2019
31046129Affective Behavior in Withdrawal Seizure-Prone and Withdrawal Seizure-Resistant Mice during Long-Term Alcohol Abstinence.Alcohol Clin Exp Res2019
30371956What Is Addiction? How Can Animal and Human Research Be Used to Advance Research, Diagnosis, and Treatment of Alcohol and Other Substance Use Disorders?Alcohol Clin Exp Res2019
30513375Genotype Differences in Sensitivity to the Anticonvulsant Effect of the Synthetic Neurosteroid Ganaxolone during Chronic Ethanol Withdrawal.Neuroscience2019
29251283Genome-Wide Expression Profiles Drive Discovery of Novel Compounds that Reduce Binge Drinking in Mice.Neuropsychopharmacology2018
30214456Stable Histone Methylation Changes at Proteoglycan Network Genes Following Ethanol Exposure.Front Genet2018
29668112Pharmacogenetic Manipulation of the Nucleus Accumbens Alters Binge-Like Alcohol Drinking in Mice.Alcohol Clin Exp Res2018
29357292Reproducibility and replicability of rodent phenotyping in preclinical studies.Neurosci Biobehav Rev2018
29427828An alcohol withdrawal test battery measuring multiple behavioral symptoms in mice.Alcohol2018
29786871Gender-Specific Effects of Selection for Drinking in the Dark on the Network Roles of Coding and Noncoding RNAs.Alcohol Clin Exp Res2018
28664280Ethanol withdrawal-induced dysregulation of neurosteroid levels in plasma, cortex, and hippocampus in genetic animal models of high and low withdrawal.Psychopharmacology (Berl)2017
28433423Prefrontal cortex expression of chromatin modifier genes in male WSP and WSR mice changes across ethanol dependence, withdrawal, and abstinence.Alcohol2017
28442218Alignment of the transcriptome with individual variation in animals selectively bred for High Drinking-In-the-Dark (HDID).Alcohol2017
28827047High Drinking in the Dark (HDID) mice are sensitive to the effects of some clinically relevant drugs to reduce binge-like drinking.Pharmacol Biochem Behav2017
25861702Protein Kinase C Epsilon Activity in the Nucleus Accumbens and Central Nucleus of the Amygdala Mediates Binge Alcohol Consumption.Biol Psychiatry2016
27588527Progress With Nonhuman Animal Models of Addiction.J Stud Alcohol Drugs2016
27716958Reproducibility of Experiments with Laboratory Animals: What Should We Do Now?Alcohol Clin Exp Res2016
27503811Effects of acute alcohol withdrawal on nest building in mice selectively bred for alcohol withdrawal severity.Physiol Behav2016
27139234Fear conditioning in mouse lines genetically selected for binge-like ethanol drinking.Alcohol2016
26779672Neuropeptide Y response to alcohol is altered in nucleus accumbens of mice selectively bred for drinking to intoxication.Behav Brain Res2016
26936805Distinct ethanol drinking microstructures in two replicate lines of mice selected for drinking to intoxication.Genes Brain Behav2016
26795092Nest building is a novel method for indexing severity of alcohol withdrawal in mice.Behav Brain Res2016
27055618Gene Targeting Studies of Hyperexcitability and Affective States of Alcohol Withdrawal in Rodents.Int Rev Neurobiol2016
23910826Rewarding and aversive effects of ethanol in High Drinking in the Dark selectively bred mice.Addict Biol2015
26431116Commonalities and Distinctions Among Mechanisms of Addiction to Alcohol and Other Drugs.Alcohol Clin Exp Res2015
25981501Distinct ethanol drinking microstructures in two replicate lines of mice selected for drinking to intoxication.Genes Brain Behav2015
25515706Genotypic and sex differences in anxiety-like behavior and alcohol-induced anxiolysis in High Drinking in the Dark selected mice.Alcohol2015
24219304Progress in a replicated selection for elevated blood ethanol concentrations in HDID mice.Genes Brain Behav2014
25581648Dual-trait selection for ethanol consumption and withdrawal: genetic and transcriptional network effects.Alcohol Clin Exp Res2014
25307569Use of animal models of alcohol-related behavior.Handb Clin Neurol2014
25306777Rodent models of genetic contributions to motivation to abuse alcohol.Nebr Symp Motiv2014
24984686"Drinking in the Dark" (DID): a simple mouse model of binge-like alcohol intake.Curr Protoc Neurosci2014
24871700Quantification of ten neuroactive steroids in plasma in Withdrawal Seizure-Prone and -Resistant mice during chronic ethanol withdrawal.Psychopharmacology (Berl)2014
24923803Identification of a QTL in Mus musculus for alcohol preference, withdrawal, and Ap3m2 expression using integrative functional genomics and precision genetics.Genetics2014
24933191Experimenter effects on behavioral test scores of eight inbred mouse strains under the influence of ethanol.Behav Brain Res2014
24612020Genetic relationship between predisposition for binge alcohol consumption and blunted sensitivity to adverse effects of alcohol in mice.Alcohol Clin Exp Res2014
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Collaborators

Portland Alcohol Research Center, Oregon Health & Science University
Co-authored papers 71
Oregon Health & Science University
Co-authored papers 68
Oregon Health & Science University
Co-authored papers 45
Oregon Health & Science University
Co-authored papers 28
Portland Alcohol Research Center, Oregon Health & Science University
Co-authored papers 17
Portland Alcohol Research Center, Oregon Health and Science University
Co-authored papers 16
Oregon Health & Science University
Co-authored papers 14
Columbia University
Co-authored papers 10
The Scripps Research Institute
Co-authored papers 9
Oregon Health & Science University, University of California Berkeley
Co-authored papers 6
Co-authored papers 6
Oregon Health & Science University
Co-authored papers 5
Center for Systems Neurogenetics of Addiction at The Jackson Laboratory
Co-authored papers 5
Mayo Clinic
Co-authored papers 5
Co-authored papers 5
McMaster University & St. Joseph's Healthcare Hamilton
Co-authored papers 4
Oregon Health & Science University
Co-authored papers 4
University of Missouri
Co-authored papers 4
Oregon Health & Science University
Co-authored papers 4
Co-authored papers 3
Co-authored papers 3
Office of the Clinical Director, National Institute on Alcohol Abuse and Alcoholism.
Co-authored papers 3
Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin
Co-authored papers 3
Oregon National Primate Research Center
Co-authored papers 3
University of Tennessee Health Science Center.
Co-authored papers 3
Virginia Commonwealth University
Co-authored papers 2
University of Colorado Health Science Center
Co-authored papers 2
Oregon National Primate Research Center, Oregon Health & Science University
Co-authored papers 2
University of North Carolina at Chapel Hill
Co-authored papers 2
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