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Author Details

Sohrab P Shah
Memorial Sloan Kettering Cancer Center
2003
127
70
PMIDPaper TitleJournal TitlePublished Year
34663944Harnessing multimodal data integration to advance precision oncology.Nat Rev Cancer2022
35380993Tumor-associated antigen PRAME exhibits dualistic functions that are targetable in diffuse large B cell lymphoma.J Clin Invest2022
35927228Accurate determination of CRISPR-mediated gene fitness in transplantable tumours.Nat Commun2022
36351924Single-cell profiling reveals a memory B cell-like subtype of follicular lymphoma with increased transformation risk.Nat Commun2022
36289342Single-cell genomic variation induced by mutational processes in cancer.Nature2022
36289203Clonal somatic copy number altered driver events inform drug sensitivity in high-grade serous ovarian cancer.Nat Commun2022
30768159Dhaka: variational autoencoder for unmasking tumor heterogeneity from single cell genomic data.Bioinformatics2021
33684939Characterization of DLBCL with a PMBL gene expression signature.Blood2021
33504553Initial Whole-Genome Sequencing of Plasma Cell Neoplasms in First Responders and Recovery Workers Exposed to the World Trade Center Attack of September 11, 2001.Clin Cancer Res2021
34615710Single-cell profiling reveals the importance of CXCL13/CXCR5 axis biology in lymphocyte-rich classic Hodgkin lymphoma.Proc Natl Acad Sci U S A2021
34115989Tim-4[+] cavity-resident macrophages impair anti-tumor CD8[+] T cell immunity.Cancer Cell2021
34163070Clonal fitness inferred from time-series modelling of single-cell cancer genomes.Nature2021
32546838Chemogenomic profiling of breast cancer patient-derived xenografts reveals targetable vulnerabilities for difficult-to-treat tumors.Commun Biol2020
32033589Eleven grand challenges in single-cell data science.Genome Biol2020
31857391Single-Cell Transcriptome Analysis Reveals Disease-Defining T-cell Subsets in the Tumor Microenvironment of Classic Hodgkin Lymphoma.Cancer Discov2020
32094924TMEM30A loss-of-function mutations drive lymphomagenesis and confer therapeutically exploitable vulnerability in B-cell lymphoma.Nat Med2020
32332753Non-coding somatic mutations converge on the PAX8 pathway in ovarian cancer.Nat Commun2020
30523716Double-Hit Gene Expression Signature Defines a Distinct Subgroup of Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma.J Clin Oncol2019
29968850Correction: TERT promoter mutation in adult granulosa cell tumor of the ovary.Mod Pathol2019
31501550Probabilistic cell-type assignment of single-cell RNA-seq for tumor microenvironment profiling.Nat Methods2019
31623682Dissociation of solid tumor tissues with cold active protease for single-cell RNA-seq minimizes conserved collagenase-associated stress responses.Genome Biol2019
31340883Molecular profiling and molecular classification of endometrioid ovarian carcinomas.Gynecol Oncol2019
30705065Molecular and Genetic Characterization of MHC Deficiency Identifies EZH2 as Therapeutic Target for Enhancing Immune Recognition.Cancer Discov2019
31088846Targeting Hypoxia-Induced Carbonic Anhydrase IX Enhances Immune-Checkpoint Blockade Locally and Systemically.Cancer Immunol Res2019
30794536Integrated structural variation and point mutation signatures in cancer genomes using correlated topic models.PLoS Comput Biol2019
30729182Somatic mutation detection and classification through probabilistic integration of clonal population information.Commun Biol2019
31078621Regulation of pH by Carbonic Anhydrase 9 Mediates Survival of Pancreatic Cancer Cells With Activated KRAS in Response to Hypoxia.Gastroenterology2019
28630229Observing Clonal Dynamics across Spatiotemporal Axes: A Prelude to Quantitative Fitness Models for Cancer.Cold Spring Harb Perspect Med2018
30158680Copy number signatures in ovarian cancer.Nat Genet2018
30275490Genome-wide discovery of somatic regulatory variants in diffuse large B-cell lymphoma.Nat Commun2018
29449679TERT promoter mutation in adult granulosa cell tumor of the ovary.Mod Pathol2018
29754820Interfaces of Malignant and Immunologic Clonal Dynamics in Ovarian Cancer.Cell2018
29784946Interpretable dimensionality reduction of single cell transcriptome data with deep generative models.Nat Commun2018
28068316Scalable whole-genome single-cell library preparation without preamplification.Nat Methods2017
28232751CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor.Nat Commun2017
28436987Genomic consequences of aberrant DNA repair mechanisms stratify ovarian cancer histotypes.Nat Genet2017
28334900CDK12 regulates alternative last exon mRNA splicing and promotes breast cancer cell invasion.Nucleic Acids Res2017
28249593ddClone: joint statistical inference of clonal populations from single cell and bulk tumour sequencing data.Genome Biol2017
28351934Genetic profiling of <i>MYC</i> and <i>BCL2</i> in diffuse large B-cell lymphoma determines cell-of-origin-specific clinical impact.Blood2017
28327945Enhancing knowledge discovery from cancer genomics data with Galaxy.Gigascience2017
28211448CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours.Nat Commun2017
29032825LINE-1 retrotransposon-mediated DNA transductions in endometriosis associated ovarian cancers.Gynecol Oncol2017
28985744Correction to: ReMixT: clone-specific genomic structure estimation in cancer.Genome Biol2017
29026114The driver landscape of sporadic chordoma.Nat Commun2017
29044127Engineered in-vitro cell line mixtures and robust evaluation of computational methods for clonal decomposition and longitudinal dynamics in cancer.Sci Rep2017
28750660ReMixT: clone-specific genomic structure estimation in cancer.Genome Biol2017
28557980E-scape: interactive visualization of single-cell phylogenetics and cancer evolution.Nat Methods2017
28898161Prognostic Model to Predict Post-Autologous Stem-Cell Transplantation Outcomes in Classical Hodgkin Lymphoma.J Clin Oncol2017
28659443Genetic and epigenetic inactivation of <i>SESTRIN1</i> controls mTORC1 and response to EZH2 inhibition in follicular lymphoma.Sci Transl Med2017
28655203Kronos: a workflow assembler for genome analytics and informatics.Gigascience2017
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Collaborators

Samuel Aparicio
University of British Columbia
Co-authored papers 42
David G Huntsman
University of British Columbia
Co-authored papers 40
Marco A Marra
University of British Columbia
Co-authored papers 38
Ali Bashashati
University of British Columbia
Co-authored papers 34
Andrew McPherson
Memorial Sloan Kettering Cancer Center
Co-authored papers 26
Janine Senz
University of British Columbia
Co-authored papers 21
Ryan D Morin
Simon Fraser University
Co-authored papers 20
Martin Hirst
University of British Columbia
Co-authored papers 19
Cyril B Gilks
University of British Columbia
Co-authored papers 18
Leah M Prentice
British Columbia Women's Hospital and Health Centre
Co-authored papers 18
David W Scott
University of British Columbia
Co-authored papers 17
Richard A Moore
Co-authored papers 16
Steven J M Jones
University of British Columbia
Co-authored papers 14
Andrew J Mungall
Co-authored papers 14
Carlos Caldas
Cancer Research UK Cambridge Institute, University of Cambridge
Co-authored papers 13
Michael S Anglesio
University of British Columbia
Co-authored papers 11
Yongjun Zhao
Canada British Columbia Cancer Research Centre, University of British Columbia
Co-authored papers 11
Steve E Kalloger
University of British Columbia
Co-authored papers 10
Jamie Rosner
University of British Columbia
Co-authored papers 10
Lauren C Chong
University of British Columbia
Co-authored papers 7
Diljot Grewal
Memorial Sloan Kettering Cancer Center
Co-authored papers 7
Cydney B Nielsen
Co-authored papers 7
Alireza Heravi-Moussavi
Ferdowsi University of Mashhad
Co-authored papers 6
Suleyman Cenk Sahinalp
National Cancer Institute, National Institutes of Health
Co-authored papers 6
Oscar M Rueda
University of Cambridge
Co-authored papers 6
Angela Tam
Co-authored papers 5
Wan L Lam
British Columbia Cancer Research Institute
Co-authored papers 5
James D Brenton
CRUK Cambridge Institute, University of Cambridge
Co-authored papers 5
Mohamed R Aniba
Telethon Kids Institute
Co-authored papers 5
Robert A Holt
BC Cancer Research Institute
Co-authored papers 5
Release 1.2