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Author Details
Full Name
Avrum Spira
Affiliation
Boston University School of Medicine
ORCID
Career Start Year
1997
Papers
165
H Index
52
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36229050
Bronchial gene expression alterations associated with radiological bronchiectasis.
Eur Respir J
2023
37500728
Single-molecule genome-wide mutation profiles of cell-free DNA for non-invasive detection of cancer.
Nat Genet
2023
37567908
Integrative genetic and genomic networks identify microRNA associated with COPD and ILD.
Sci Rep
2023
37150829
Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression.
J Exp Clin Cancer Res
2023
37477508
Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma.
Cancer Res
2023
33972452
Bronchial gene expression signature associated with rate of subsequent FEV<sub>1</sub> decline in individuals with and at risk of COPD.
Thorax
2022
35740559
Clinical Study of Aspirin and Zileuton on Biomarkers of Tobacco-Related Carcinogenesis in Current Smokers.
Cancers (Basel)
2022
35830375
Clinical validation and utility of Percepta GSC for the evaluation of lung cancer.
PLoS One
2022
36307504
Smoking modulates different secretory subpopulations expressing SARS-CoV-2 entry genes in the nasal and bronchial airways.
Sci Rep
2022
36098652
The Single-Cell Immunogenomic Landscape of B and Plasma Cells in Early-Stage Lung Adenocarcinoma.
Cancer Discov
2022
34675046
The molecular and cellular mechanisms associated with the destruction of terminal bronchioles in COPD.
Eur Respir J
2022
32758562
Impact of the Percepta Genomic Classifier on Clinical Management Decisions in a Multicenter Prospective Study.
Chest
2021
33903236
Aberrant epithelial polarity cues drive the development of precancerous airway lesions.
Proc Natl Acad Sci U S A
2021
33862585
The transition from normal lung anatomy to minimal and established fibrosis in idiopathic pulmonary fibrosis (IPF).
EBioMedicine
2021
33809063
Single-Cell Expression Landscape of SARS-CoV-2 Receptor <i>ACE2</i> and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients.
Cancers (Basel)
2021
34794107
Pathologic and gene expression comparison of CT- screen detected and routinely detected stage I/0 lung adenocarcinoma in NCCN risk-matched cohorts.
Cancer Treat Res Commun
2021
34464235
Integrated Biomarkers for the Management of Indeterminate Pulmonary Nodules.
Am J Respir Crit Care Med
2021
34580161
Elevated T cell repertoire diversity is associated with progression of lung squamous cell premalignant lesions.
J Immunother Cancer
2021
33972311
Resolving the Spatial and Cellular Architecture of Lung Adenocarcinoma by Multiregion Single-Cell Sequencing.
Cancer Discov
2021
32946850
Distinguishing Smoking-Related Lung Disease Phenotypes Via Imaging and Molecular Features.
Chest
2021
32730093
Augmented Lipocalin-2 Is Associated with Chronic Obstructive Pulmonary Disease and Counteracts Lung Adenocarcinoma Development.
Am J Respir Crit Care Med
2021
31610044
Characterizing peak exposure of secondhand smoke using a real-time PM<sub>2.5</sub> monitor.
Indoor Air
2020
32044442
Transcriptomic changes in the nasal epithelium associated with diesel engine exhaust exposure.
Environ Int
2020
33060632
Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD.
Sci Rep
2020
33093160
Biomarkers for Lung Cancer Screening and Detection.
Cancer Epidemiol Biomarkers Prev
2020
32512511
Low oxygen saturation during sleep reduces CD1D and RAB20 expressions that are reversed by CPAP therapy.
EBioMedicine
2020
30529598
Biomarkers in Lung Cancer Screening: Achievements, Promises, and Challenges.
J Thorac Oncol
2019
31844660
Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution.
Sci Adv
2019
31233743
Gene Expression Alterations in the Bronchial Epithelium of e-Cigarette Users.
Chest
2019
31451521
Effect of Intermittent Versus Continuous Low-Dose Aspirin on Nasal Epithelium Gene Expression in Current Smokers: A Randomized, Double-Blinded Trial.
Cancer Prev Res (Phila)
2019
31015447
Molecular subtyping reveals immune alterations associated with progression of bronchial premalignant lesions.
Nat Commun
2019
30896962
Driver Mutations in Normal Airway Epithelium Elucidate Spatiotemporal Resolution of Lung Cancer.
Am J Respir Crit Care Med
2019
31061400
Tobacco-Related Alterations in Airway Gene Expression are Rapidly Reversed Within Weeks Following Smoking-Cessation.
Sci Rep
2019
31142513
The Immune Contexture Associates with the Genomic Landscape in Lung Adenomatous Premalignancy.
Cancer Res
2019
30846474
Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in COPD.
Eur Respir J
2019
30845938
Detection of early lung cancer among military personnel (DECAMP) consortium: study protocols.
BMC Pulm Med
2019
30464018
Electronic cigarettes: a task force report from the European Respiratory Society.
Eur Respir J
2019
30664780
Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions.
Nat Med
2019
30383540
An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup.
J Clin Invest
2019
29072842
Impact of Chronic Obstructive Pulmonary Disease on Immune-based Treatment for Lung Cancer. Moving toward Disease Interception.
Am J Respir Crit Care Med
2018
30072506
microRNA-mRNA regulatory networks underlying chronic mucus hypersecretion in COPD.
Eur Respir J
2018
29932825
Impact of acute exposure to cigarette smoke on airway gene expression.
Physiol Genomics
2018
30425966
Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the <i>TBX2</i> Subfamily of Tumor Suppressor Genes.
Front Oncol
2018
30640517
Current Status and Future Opportunities in Lung Precision Medicine Research with a Focus on Biomarkers. An American Thoracic Society/National Heart, Lung, and Blood Institute Research Statement.
Am J Respir Crit Care Med
2018
29382653
Genome-Wide Gene Expression Changes in the Normal-Appearing Airway during the Evolution of Smoking-Associated Lung Adenocarcinoma.
Cancer Prev Res (Phila)
2018
29463557
The Airway Transcriptome as a Biomarker for Early Lung Cancer Detection.
Clin Cancer Res
2018
29601802
Impact of an Interdisciplinary Computational Research Section in a Department of Medicine: An 8-Year Perspective.
Am J Med
2018
29510677
Summarizing performance for genome scale measurement of miRNA: reference samples and metrics.
BMC Genomics
2018
29624449
Defining Impaired Respiratory Health. A Paradigm Shift for Pulmonary Medicine.
Am J Respir Crit Care Med
2018
27856720
Nondestructive cryomicro-CT imaging enables structural and molecular analysis of human lung tissue.
J Appl Physiol (1985)
2017
1 - 50 of 165
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Co-authored papers
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The University of Texas MD Anderson Cancer Center
Co-authored papers
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Scott M Lippman
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Co-authored papers
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Jerry Fowler
The University of Texas MD Anderson Cancer Center
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