Author details

Full Name

Dmitry M Korzhnev

Affiliation

University of Connecticut Health Center

ORCID

Career Start Year

1995

Papers

H Index

Expertise

CM4AI Collaborator

Andrej Sali (CM4AI)

PMID	Paper Title	Journal Title	Published Year
36711877	Activation Dynamics of Ubiquitin Specific Protease 7.	bioRxiv	2023
37473756	Conformational exchange at a C<sub>2</sub>H<sub>2</sub> zinc-binding site facilitates redox sensing by the PML protein.	Structure	2023
37129702	Backbone and ILV side-chain methyl NMR resonance assignments of human Rev7/Rev3-RBM1 and Rev7/Rev3-RBM2 complexes.	Biomol NMR Assign	2023
36592930	Evolution of Rev7 interactions in eukaryotic TLS DNA polymerase PolÎ¶.	J Biol Chem	2023
35192840	Architecture of the two metal-binding sites inÂ prolactin.	Biophys J	2022
35608245	DNA Sequence Specificity Reveals a Role of the HLTF HIRAN Domain in the Recognition of Trinucleotide Repeats.	Biochemistry	2022
35536398	Backbone and ILV side-chain NMR resonance assignments of the catalytic domain of human deubiquitinating enzyme USP7.	Biomol NMR Assign	2022
35687262	ILV methyl NMR resonance assignments of the 81Â kDa E. coli Î²-clamp.	Biomol NMR Assign	2022
33314657	Structure-Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis.	ChemMedChem	2021
33761093	NMR resonance assignments for the nucleotide binding domains of the E. coli clamp loader complex Î³ subunit.	Biomol NMR Assign	2021
34458830	Targeting protein-protein interactions in the DNA damage response pathways for cancer chemotherapy.	RSC Chem Biol	2021
34771454	REV1 Inhibition Enhances Radioresistance and Autophagy.	Cancers (Basel)	2021
31361935	Virtual Pharmacophore Screening Identifies Small-Molecule Inhibitors of the Rev1-CT/RIR Protein-Protein Interaction.	ChemMedChem	2019
31627876	The Rev1-PolÎ¶ translesion synthesis mutasome: Structure, interactions and inhibition.	Enzymes	2019
30289707	Structural Approach To Identify a Lead Scaffold That Targets the Translesion Synthesis Polymerase Rev1.	J Chem Inf Model	2018
30207151	Conformational Dynamics of a Cysteine-Stabilized Plant Defensin Reveals an Evolutionary Mechanism to Expose Hydrophobic Residues.	Biochemistry	2018
30037752	Small molecule scaffolds that disrupt the Rev1-CT/RIR protein-protein interaction.	Bioorg Med Chem	2018
30111544	Rev7 dimerization is important for assembly and function of the Rev1/PolÎ¶ translesion synthesis complex.	Proc Natl Acad Sci U S A	2018
28552172	Protein folding by NMR.	Prog Nucl Magn Reson Spectrosc	2017
28401755	Structural Characterization of the Early Events in the Nucleation-Condensation Mechanism in a Protein Folding Process.	J Am Chem Soc	2017
28265855	NMR resonance assignments for the N-terminal domain of the Î´ subunit of the E. coli Î³ clamp loader complex.	Biomol NMR Assign	2017
28541665	Identification of Small Molecule Translesion Synthesis Inhibitors That Target the Rev1-CT/RIR Protein-Protein Interaction.	ACS Chem Biol	2017
26982350	Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of PolÎ¶ Suggests a Mechanism of Polymerase Exchange upon Rev1/PolÎ¶-Dependent Translesion Synthesis.	Biochemistry	2016
27771863	Solution NMR structure of the HLTF HIRAN domain: a conserved module in SWI2/SNF2 DNA damage tolerance proteins.	J Biomol NMR	2016
27362876	Targeting the Translesion Synthesis Pathway for the Development of Anti-Cancer Chemotherapeutics.	J Med Chem	2016
26115097	Probing the Residual Structure of the Low Populated Denatured State of ADA2h under Folding Conditions by Relaxation Dispersion Nuclear Magnetic Resonance Spectroscopy.	Biochemistry	2015
26051180	HLTF's Ancient HIRAN Domain Binds 3' DNA Ends to Drive Replication Fork Reversal.	Mol Cell	2015
26224631	Structural Characterization of Interaction between Human Ubiquitin-specific Protease 7 and Immediate-Early Protein ICP0 of Herpes Simplex Virus-1.	J Biol Chem	2015
25162118	NMR structure of the human Rad18 zinc finger in complex with ubiquitin defines a class of UBZ domains in proteins linked to the DNA damage response.	Biochemistry	2014
23084974	Loss of structure-gain of function.	J Mol Biol	2013
23907177	PHD domain from human SHPRH.	J Biomol NMR	2013
23747975	NMR mapping of PCNA interaction with translesion synthesis DNA polymerase Rev1 mediated by Rev1-BRCT domain.	J Mol Biol	2013
22148426	Cross-validation of the structure of a transiently formed and low populated FF domain folding intermediate determined by relaxation dispersion NMR and CS-Rosetta.	J Phys Chem B	2012
22955930	In support of the BMRB.	Nat Struct Mol Biol	2012
22691049	NMR structure and dynamics of the C-terminal domain from human Rev1 and its complex with Rev1 interacting region of DNA polymerase Î·.	Biochemistry	2012
22828282	The C-terminal domain of human Rev1 contains independent binding sites for DNA polymerase Î· and Rev7 subunit of polymerase Î¶.	FEBS Lett	2012
22647611	Transiently populated intermediate functions as a branching point of the FF domain folding pathway.	Proc Natl Acad Sci U S A	2012
21639149	Nonnative interactions in the FF domain folding pathway from an atomic resolution structure of a sparsely populated intermediate: an NMR relaxation dispersion study.	J Am Chem Soc	2011
20033258	Measurement of signs of chemical shift differences between ground and excited protein states: a comparison between H(S/M)QC and R1rho methods.	J Biomol NMR	2010
20829478	A transient and low-populated protein-folding intermediate at atomic resolution.	Science	2010
20799727	NMR characterization of copper-binding domains 4-6 of ATP7B .	Biochemistry	2010
20428928	A simple method for measuring signs of (1)H (N) chemical shift differences between ground and excited protein states.	J Biomol NMR	2010
19111555	Alternate binding modes for a ubiquitin-SH3 domain interaction studied by NMR spectroscopy.	J Mol Biol	2009
19569643	An analysis of the effects of 1HN-(1)HN dipolar couplings on the measurement of amide bond vector orientations in invisible protein states by relaxation dispersion NMR.	J Phys Chem B	2009
18275162	Probing invisible, low-populated States of protein molecules by relaxation dispersion NMR spectroscopy: an application to protein folding.	Acc Chem Res	2008
17306298	Propagation of dynamic changes in barnase upon binding of barstar: an NMR and computational study.	J Mol Biol	2007
17726107	Conformational instability of the MARK3 UBA domain compromises ubiquitin recognition and promotes interaction with the adjacent kinase domain.	Proc Natl Acad Sci U S A	2007
17689561	The folding pathway of an FF domain: characterization of an on-pathway intermediate state under folding conditions by (15)N, (13)C(alpha) and (13)C-methyl relaxation dispersion and (1)H/(2)H-exchange NMR spectroscopy.	J Mol Biol	2007
16608362	Probing the transition state ensemble of a protein folding reaction by pressure-dependent NMR relaxation dispersion.	J Am Chem Soc	2006
16922492	Abp1p and Fyn SH3 domains fold through similar low-populated intermediate states.	Biochemistry	2006

1 - 50 of 75

Navratna Vajpai

Biocon Research Limited - SEZ Unit

Career Start Year 2006

Number of shared co-authors 4

Nicolas L Fawzi

Brown University

Career Start Year 2003

Number of shared co-authors 2

Aleksandras Gutmanas

European Bioinformatics Institute

Career Start Year 2002

Number of shared co-authors 10

Frank Gabel

University Grenoble Alpes, CNRS

Career Start Year 2002

Number of shared co-authors 5

Henry van den Bedem

University of California San Francisco

Career Start Year 2002

Number of shared co-authors 1

Yang Shen

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Career Start Year 2002

Number of shared co-authors 7

Sayan Gupta

Lawrence Berkeley National Laboratory

Career Start Year 2001

Number of shared co-authors 0

Ronald D Seidel

Albert Einstein College of Medicine

Career Start Year 2001

Number of shared co-authors 2

Mark J S Kelly

Department of Pharmaceutical Chemistry, University of California San Francisco

Career Start Year 2000

Number of shared co-authors 5

Igor Zhukov

Institute of Biochemistry and Biophysics, Polish Academy of Sciences

Career Start Year 1999

Number of shared co-authors 1

Nikolay V Dokholyan

Pennsylvania State University College of Medicine

Career Start Year 1998

Number of shared co-authors 4

Li-Chung Ma

Robert Wood Johnson Medical School, The State University of New Jersey

Career Start Year 1997

Number of shared co-authors 5

Yuanpeng J Huang

Center for Advanced Biotechnology and Medicine, The State University of New Jersey

Career Start Year 1996

Number of shared co-authors 8

Ram??n Campos-Olivas

Spanish National Cancer Research Centre (CNIO)

Career Start Year 1995

Number of shared co-authors 3

Volker D??tsch

Institute for Biophysical Chemistry, Goethe-University

Career Start Year 1995

Number of shared co-authors 6

John R Cort

Pacific Northwest National Laboratory

Career Start Year 1994

Number of shared co-authors 3

Yunyu Shi

University of Science & Technology of China

Career Start Year 1993

Number of shared co-authors 4

Michael A Kennedy

Miami University

Career Start Year 1993

Number of shared co-authors 8

James J Chou

Harvard Medical School

Career Start Year 1993

Number of shared co-authors 5

Lorna J Smith

University of Oxford

Career Start Year 1991

Number of shared co-authors 5

Charles D Schwieters

National Institute of Diabetes and Digestive and Kidney Diseases

Career Start Year 1991

Number of shared co-authors 11

David Fushman

University of Maryland, College Park

Career Start Year 1990

Number of shared co-authors 4

Hiroshi Matsuo

Frederick National Laboratory for Cancer Research

Career Start Year 1990

Number of shared co-authors 1

Tobin R Sosnick

Institute for Biophysical Dynamics, The University of Chicago

Career Start Year 1990

Number of shared co-authors 7

Victoria A Feher

University of California San Diego

Career Start Year 1989

Number of shared co-authors 2

Roland Riek

ETH Zurich

Career Start Year 1986

Number of shared co-authors 7

Michael Nilges

Institut Pasteur

Career Start Year 1986

Number of shared co-authors 23

Gaetano T Montelione

Rensselaer Polytechnic Institute

Career Start Year 1981

Number of shared co-authors 15

Peter Bayer

University of Duisburg-Essen

Career Start Year 1981

Number of shared co-authors 3

David Cowburn

Albert Einstein College of Medicine

Career Start Year 1969

Number of shared co-authors 4

row(s) 1 - 30 of 30

Lewis E Kay

University of Toronto

Co-authored papers 29

Irina Bezsonova

University of Connecticut Health Center

Co-authored papers 18

Michele Vendruscolo

University of Cambridge

Co-authored papers 4

Alan R Fersht

Medical Research Council Laboratory of Molecular Biology

Co-authored papers 4

Julie D Forman-Kay

Hospital for Sick Children

Co-authored papers 3

Alan R Davidson

University of Toronto, University Avenue

Co-authored papers 3

Sirano Dhe-Paganon

Dana-Farber Cancer Institute

Co-authored papers 2

Cheryl H Arrowsmith

University of Toronto

Co-authored papers 2

Mark W Maciejewski

University of Connecticut School of Medicine

Co-authored papers 2

Jeffrey C Hoch

University of Connecticut Health Center

Co-authored papers 2

Andrej Sali (CM4AI)

University of California San Francisco

Co-authored papers 1

David A Case

Rutgers University

Co-authored papers 1

Oliver F Lange

Center for Integrated Protein Science, Technische Universitat Munchen

Co-authored papers 1

Gordon C K Roberts

Leicester Institute of Structural and Chemical Biology, University of Leicester

Co-authored papers 1

Josep Rizo

University of Texas Southwestern Medical Center

Co-authored papers 1

Mike P Williamson

The University of Sheffield

Co-authored papers 1

Lu-Yun Lian

Institute of Systems, The University of Liverpool

Co-authored papers 1

Igor L Barsukov

Institute of Integrative Biology, University of Liverpool

Co-authored papers 1

David E Shaw

Columbia University

Co-authored papers 1

Ad Bax

National Institutes of Health

Co-authored papers 1

Patrick C A van der Wel

Zernike Institute for Advanced Materials, University of Groningen

Co-authored papers 1

David Middleton

Co-authored papers 1

Ioannis Vakonakis

University of Oxford

Co-authored papers 1

Thomas A Frenkiel

The Medical Research Council Biomedical NMR Centre, The Francis Crick Institute

Co-authored papers 1

Ernest D Laue

University of Cambridge

Co-authored papers 1

Gordon S Rule

Carnegie Mellon University

Co-authored papers 1

Stephen Matthews

Imperial College London

Co-authored papers 1

Chien Ho

Carnegie Mellon University

Co-authored papers 1

Toshimichi Fujiwara

Institute for Protein Research, Osaka University

Co-authored papers 1

Pei Tang

Sichuan University

Co-authored papers 1

1 - 30

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