Author details

Full Name

Jin Zhang

Affiliation

ORCID

Career Start Year

2001

Papers

174

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36976866	Arrestin-dependent nuclear export of phosphodiesterase 4D promotes GPCR-induced nuclear cAMP signaling required for learning and memory.		2023
37747358	Fluorescent biosensor imaging meets deterministic mathematical modelling: quantitative investigation of signalling compartmentalization.		2023
35286687	Measuring Spatiotemporal cAMP Dynamics Within an Endogenous Signaling Compartment Using FluoSTEP-ICUE.	Methods in Molecular Biology	2022
36173169	A genetically encoded far-red fluorescent calcium ion biosensor derived from a biliverdin-binding protein.	Protein Science	2022
36167077	Dimerization of Î²-adrenergic receptor is responsible for the constitutive activity subjected to inverse agonism.	Cell Chemical Biology	2022
36289326	Non-canonical Î²-adrenergic activation of ERK at endosomes.	Nature	2022
36288358	An integrated multi-omics analysis of topoisomerase family in pan-cancer: Friend or foe?	PLoS ONE	2022
36347198	Study of spatiotemporal regulation of kinase signaling using genetically encodable molecular tools.	Current Opinion in Chemical Biology	2022
35790710	Spatial regulation of AMPK signaling revealed by a sensitive kinase activity reporter.	Nature Communications	2022
36122391	Fluorescent Biosensor for Measuring Ras Activity in Living Cells.	Journal of the American Chemical Society	2022
35784154	Circ_0138959/miR-495-3p/TRAF6 axis regulates proliferation, wound healing and osteoblastic differentiation of periodontal ligament cells in periodontitis.	Journal of Dental Sciences	2022
35532280	AktAR and Akt-STOPS: Genetically Encodable Molecular Tools to Visualize and Perturb Akt Kinase Activity at Different Subcellular Locations in Living Cells.	Current Protocols	2022
36566209	Engineering inducible biomolecular assemblies for genome imaging and manipulation in living cells.	Nat Commun	2022
36543345	Role of autophagy in lung diseases and ageing.		2022
35294906	Rheb regulates nuclear mTORC1 activity independent of farnesylation.	Cell Chem Biol	2022
34847077	Î²3-Adrenergic receptor downregulation leads to adipocyte catecholamine resistance in obesity.	J Clin Invest	2022
35149762	Liquid-liquid phase separation drives cellular function and dysfunction in cancer.	Nature Reviews Cancer	2022
34413312	Integration of FRET and sequencing to engineer kinase biosensors from mammalian cell libraries.	Nat Commun	2021
34020947	FluoSTEPs: Fluorescent biosensors for monitoring compartmentalized signaling within endogenous microdomains.	Sci Adv	2021
34059826	A pairwise distance distribution correction (DDC) algorithm to eliminate blinking-caused artifacts in SMLM.	Nat Methods	2021
33790271	Simultaneous readout of multiple FRET pairs using photochromism.	Nature Communications	2021
33949851	Biochemical Activity Architectures Visualized-Using Genetically Encoded Fluorescent Biosensors to Map the Spatial Boundaries of Signaling Compartments.	Accounts of Chemical Research	2021
34192547	FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes.	Cell Rep	2021
34027037	Regulation of nuclear mTORC1.	Molecular and Cellular Oncology	2021
34331275	Strategies for Multiplexed Biosensor Imaging to Study Intracellular Signaling Networks.	Methods in Molecular Biology	2021
32989297	An ultrasensitive biosensor for high-resolution kinase activity imaging in awake mice.	Nature Chemical Biology	2021
33345445	Cancer-secreted miRNAs regulate amino-acid-induced mTORC1 signaling and fibroblast protein synthesis.	EMBO Reports	2021
33411579	Signaling Microdomains in the Spotlight: Visualizing Compartmentalized Signaling Using Genetically Encoded Fluorescent Biosensors.	Annual Review of Pharmacology and Toxicology	2021
34467224	Protocol for using fluorescent sensors targeted to endogenous proteins (FluoSTEPs) to measure microdomain-specific signaling events.	STAR Protocols	2021
34572144	Glucagon Potentiates Insulin Secretion Via Î²-Cell GCGR at Physiological Concentrations of Glucose.	Cells	2021
34516108	DrFLINC Contextualizes Super-resolution Activity Imaging.	Journal of the American Chemical Society	2021
34619090	Liquid-liquid phase separation: Orchestrating cell signaling through time and space.	Molecular Cell	2021
34963894	A Highly Sensitive Fluorescent Akt Biosensor Reveals Lysosome-Selective Regulation of Lipid Second Messengers and Kinase Activity.	ACS Central Science	2021
34373114	Liquid-liquid phase separation: a principal organizer of the cell's biochemical activity architecture.	Trends in Pharmacological Sciences	2021
32660810	Genetically Encodable Fluorescent and Bioluminescent Biosensors Light Up Signaling Networks.	Trends in Biochemical Sciences	2020
31855412	Fluorescent Biosensors for Multiplexed Imaging of Phosphoinositide Dynamics.	ACS Chemical Biology	2020
31911398	Illuminating the kinome: Visualizing real-time kinase activity in biological systems using genetically encoded fluorescent protein-based biosensors.	Current Opinion in Chemical Biology	2020
31948942	An ABC Transporter Drives Medulloblastoma Pathogenesis by Regulating Sonic Hedgehog Signaling.	Cancer Res	2020
32058267	Recent advances in the use of genetically encodable optical tools to elicit and monitor signaling events.	Current Opinion in Cell Biology	2020
32296061	A rationally enhanced red fluorescent protein expands the utility of FRET biosensors.	Nature Communications	2020
33257668	Location-specific inhibition of Akt reveals regulation of mTORC1 activity in the nucleus.	Nat Commun	2020
33201801	Spatially compartmentalized phase regulation of a Ca-cAMP-PKA oscillatory circuit.	eLife	2020
31423459	Triple Fluorescence Anisotropy Reporter Imaging in Living Cells.	Bio-protocol	2019
31668749	Computational Modeling Reveals Frequency Modulation of Calcium-cAMP/PKA Pathway in Dendritic Spines.	Biophysical Journal	2019
33163483	for Ratiometric and High-Throughput Live-Cell Image Visualization and Quantitation.	Frontiers in Physics	2019
30982750	AKAP95 Organizes a Nuclear Microdomain to Control Local cAMP for Regulating Nuclear PKA.	Cell Chemical Biology	2019
31434714	Genetically encoded fluorescent biosensors illuminate kinase signaling in cancer.	Journal of Biological Chemistry	2019
30664778	A genetically encoded near-infrared fluorescent calcium ion indicator.	Nat Methods	2019
29540527	A biosensor for MAPK-dependent Lin28 signaling.	Molecular Biology of the Cell	2018
28613457	Live-cell imaging of cell signaling using genetically encoded fluorescent reporters.		2018