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Author Details

Hidekazu Tsukamoto
University of Michigan ann arbor
1984
220
74
PMIDPaper TitleJournal TitlePublished Year
36181700Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis.Hepatology2023
37156770Hepatic stellate cell stearoyl co-A desaturase activates leukotriene B4 receptor 2 - β-catenin cascade to promote liver tumorigenesis.Nat Commun2023
36949755LIN28 and histone H3K4 methylase induce TLR4 to generate tumor-initiating stem-like cells.iScience2023
37448562Polycomb repressive complex 2 binds and stabilizes NANOG to suppress differentiation-related genes to promote self-renewal.iScience2023
37026704miR-34a regulates macrophage-associated inflammation and angiogenesis in alcohol-induced liver injury.Hepatol Commun2023
36595671Circadian regulator BMAL1::CLOCK promotes cell proliferation in hepatocellular carcinoma by controlling apoptosis and cell cycle.Proc Natl Acad Sci U S A2023
35264978Cell-to-Cell Communications in Alcohol-Associated Liver Disease.Front Physiol2022
35941112Acetate reprograms gut microbiota during alcohol consumption.Nat Commun2022
34859965Concomitant genetic defects potentiate the adverse impact of prenatal alcohol exposure on cardiac outflow tract maturation.Birth Defects Res2022
30917630Cell Death and Liver Disease.Gut Liver2020
31899206IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease.J Hepatol2020
31838050Stearoyl-CoA desaturase and tumorigenesis.Chem Biol Interact2020
32051339Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice.JCI Insight2020
31945016Epithelial splicing regulatory protein 2-mediated alternative splicing reprograms hepatocytes in severe alcoholic hepatitis.J Clin Invest2020
31760766Moderate alcohol intake promotes pancreatic ductal adenocarcinoma development in mice expressing oncogenic Kras.Am J Physiol Gastrointest Liver Physiol2020
33053933The 14th International Symposium on Alcoholic Liver and Pancreatic Diseases and Cirrhosis (ISALPDC).Clin Mol Hepatol2020
33173221Fate and functional roles of Prominin 1<sup>+</sup> cells in liver injury and cancer.Sci Rep2020
32154597Differential Activation of Unconventional T Cells, Including iNKT Cells, in Alcohol-Related Liver Disease.Alcohol Clin Exp Res2020
32555153p53 destabilizing protein skews asymmetric division and enhances NOTCH activation to direct self-renewal of TICs.Nat Commun2020
32258954Primary Alcohol-Activated Human and Mouse Hepatic Stellate Cells Share Similarities in Gene-Expression Profiles.Hepatol Commun2020
32556367Comprehensive characterization of hepatocyte-derived extracellular vesicles identifies direct miRNA-based regulation of hepatic stellate cells and DAMP-based hepatic macrophage IL-1β and IL-17 upregulation in alcoholic hepatitis mice.J Mol Med (Berl)2020
30643981Alcoholic and non-alcoholic steatohepatitis: global perspective and emerging science.J Gastroenterol2019
30763905Summary of the 2018 Alcohol and Immunology Research Interest Group (AIRIG) meeting.Alcohol2019
30658726Inflammatory pathways in alcoholic steatohepatitis.J Hepatol2019
29108122Pyroptosis by caspase11/4-gasdermin-D pathway in alcoholic hepatitis in mice and patients.Hepatology2018
30154473Publisher Correction: Alcoholic liver disease.Nat Rev Dis Primers2018
30115921Alcoholic liver disease.Nat Rev Dis Primers2018
29729190Baicalein Targets GTPase-Mediated Autophagy to Eliminate Liver Tumor-Initiating Stem Cell-Like Cells Resistant to mTORC1 Inhibition.Hepatology2018
28942194The 2-oxoglutarate carrier promotes liver cancer by sustaining mitochondrial GSH despite cholesterol loading.Redox Biol2018
27639178Extracellular vesicles released by hepatocytes from gastric infusion model of alcoholic liver disease contain a MicroRNA barcode that can be detected in blood.Hepatology2017
28129116A Proof-of-Concept for Epigenetic Therapy of Tissue Fibrosis: Inhibition of Liver Fibrosis Progression by 3-Deazaneplanocin A.Mol Ther2017
28157489Cathepsin H-Mediated Degradation of HDAC4 for Matrix Metalloproteinase Expression in Hepatic Stellate Cells: Implications of Epigenetic Suppression of Matrix Metalloproteinases in Fibrosis through Stabilization of Class IIa Histone Deacetylases.Am J Pathol2017
28143772Stearoyl-CoA Desaturase Promotes Liver Fibrosis and Tumor Development in Mice via a Wnt Positive-Signaling Loop by Stabilization of Low-Density Lipoprotein-Receptor-Related Proteins 5 and 6.Gastroenterology2017
28114741Loss of the transforming growth factor-β effector β2-Spectrin promotes genomic instability.Hepatology2017
28536261The let-7/Lin28 axis regulates activation of hepatic stellate cells in alcoholic liver injury.J Biol Chem2017
28797077Gender difference in NASH susceptibility: Roles of hepatocyte Ikkβ and Sult1e1.PLoS One2017
26784546TGF-β/β2-spectrin/CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome.J Clin Invest2016
27965585A Mouse Intra-Intestinal Infusion Model and its Application to the Study of Nanoparticle Distribution.Front Physiol2016
27895587Vitamin D Signaling through Induction of Paneth Cell Defensins Maintains Gut Microbiota and Improves Metabolic Disorders and Hepatic Steatosis in Animal Models.Front Physiol2016
27239399The role of IL-17 signaling in regulation of the liver-brain axis and intestinal permeability in Alcoholic Liver Disease.Curr Pathobiol Rep2016
27214381Wnt Pathway Stabilizes MeCP2 Protein to Repress PPAR-γ in Activation of Hepatic Stellate Cells.PLoS One2016
27401171Uncovering the liver's role in immunity through RNA co-expression networks.Mamm Genome2016
27020313Alcohol produces distinct hepatic lipidome and eicosanoid signature in lean and obese.J Lipid Res2016
26940353Alcoholic hepatitis: Translational approaches to develop targeted therapies.Hepatology2016
26826669Inflammation in Alcoholic and Nonalcoholic Fatty Liver Disease: Friend or Foe?Gastroenterology2016
25132354Osteopontin deficiency does not prevent but promotes alcoholic neutrophilic hepatitis in mice.Hepatology2015
26343518Notch, metabolism and macrophages.Oncotarget2015
26189984Notch signaling and M1 macrophage activation in obesity-alcohol synergism.Clin Res Hepatol Gastroenterol2015
26206577Morphogen-related therapeutic targets for liver fibrosis.Clin Res Hepatol Gastroenterol2015
26206575ALPD 2015, Preface.Clin Res Hepatol Gastroenterol2015
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Collaborators

Samuel W French
Co-authored papers 28
Jiaohong Wang
Cedars-Sinai Medical Center (CSMC)
Co-authored papers 16
David A Brenner
Co-authored papers 12
Raymond Wu
Southern California Research Center for ALPD and Cirrhosis
Co-authored papers 10
Bernd Schnabl
University of California San Diego
Co-authored papers 7
Yibu Chen
USC Libraries Bioinformatic Services of the University of Southern California
Co-authored papers 7
Raul Lazaro
Keck School of Medicine of the University of Southern California
Co-authored papers 7
Stephanie Q Pan
Keck School of Medicine of the University of Southern California
Co-authored papers 6
Michael Karin
Co-authored papers 6
Tatiana Kisseleva
Co-authored papers 6
Gary M Brittenham
Columbia University Vagelos College of Physicians and Surgeons
Co-authored papers 5
Peter St??rkel
Cliniques Universitaires Saint-Luc (CUSL)
Co-authored papers 4
Ariel E Feldstein
University of California San Diego
Co-authored papers 3
Christopher Benner
Michigan State University College of Human Medicine
Co-authored papers 3
Rui Yan
Affiliated Hospital of Guizhou Medical University
Co-authored papers 3
Sara Brin Rosenthal
Center for Computational Biology and Bioinformatics, University of California
Co-authored papers 3
Akiko Eguchi
Mie University Graduate School of Medicine
Co-authored papers 3
Samuel B Ho
College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences
Co-authored papers 3
Richard D Smith
Pacific Northwest National Laboratory
Co-authored papers 2
Lucila Ohno-Machado
Escola de Administracao de Empresas - FGV, Stanford University, University of California San Diego, University of Sao Paulo, Yale School of Medicine
Co-authored papers 2
Christopher K Glass
University of California San Diego
Co-authored papers 2
Amanda J Roberts
The Scripps Research Institute
Co-authored papers 2
Zhixiong Xiao
Co-authored papers 2
Lucila Ohno-Machado
Co-authored papers 2
Victor R Gordeuk
Co-authored papers 2
Charles Ansong
Pacific Northwest National Laboratory
Co-authored papers 2
Yaoqi Alan Wang
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Ivan Rusyn
Co-authored papers 2
Yoshiyuki Takei
Mie University
Co-authored papers 2
Ekihiro Seki
Co-authored papers 2
Release 1.2