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Author Details

Lian Duan
Brown University
2006
61
20
PMIDPaper TitleJournal TitlePublished Year
31071600Cytotoxic phenolic constituents from Hypericum japonicum.Phytochemistry2019
28967743Substitution of Aromatic Residues with Polar Residues in the Active Site Pocket of epi-Isozizaene Synthase Leads to the Generation of New Cyclic Sesquiterpenes.Biochemistry2017
28362483Exploring the Influence of Domain Architecture on the Catalytic Function of Diterpene Synthases.Biochemistry2017
27588339The Cytochrome P450-Catalyzed Oxidative Rearrangement in the Final Step of Pentalenolactone Biosynthesis: Substrate Structure Determines Mechanism.J Am Chem Soc2016
24333382Membrane attachment and structure models of lipid storage droplet protein 1.Biochim Biophys Acta2014
23395072HCN2/SkM1 gene transfer into canine left bundle branch induces stable, autonomically responsive biological pacing at physiological heart rates.J Am Coll Cardiol2013
22520750Insights into quinaldic acid moiety formation in thiostrepton biosynthesis facilitating fluorinated thiopeptide generation.Chem Biol2012
23029291ThioFinder: a web-based tool for the identification of thiopeptide gene clusters in DNA sequences.PLoS One2012
22753192Ca(2+)-stimulated adenylyl cyclase AC1 generates efficient biological pacing as single gene therapy and in combination with HCN2.Circulation2012
22722661Effect of skeletal muscle Na(+) channel delivered via a cell platform on cardiac conduction and arrhythmia induction.Circ Arrhythm Electrophysiol2012
22480202Structure-based classification and ontology in chemistry.J Cheminform2012
21240261Radical-mediated enzymatic carbon chain fragmentation-recombination.Nat Chem Biol2011
19913036Bacterial pleckstrin homology domains: a prokaryotic origin for the PH domain.J Mol Biol2010
21047073NosA catalyzing carboxyl-terminal amide formation in nosiheptide maturation via an enamine dealkylation on the serine-extended precursor peptide.J Am Chem Soc2010
20836087The crystal structure of a bacterial Sufu-like protein defines a novel group of bacterial proteins that are similar to the N-terminal domain of human Sufu.Protein Sci2010
20944232Structure of the γ-D-glutamyl-L-diamino acid endopeptidase YkfC from Bacillus cereus in complex with L-Ala-γ-D-Glu: insights into substrate recognition by NlpC/P60 cysteine peptidases.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944231Conformational changes associated with the binding of zinc acetate at the putative active site of XcTcmJ, a cupin from Xanthomonas campestris pv. campestris.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944230Structures of three members of Pfam PF02663 (FmdE) implicated in microbial methanogenesis reveal a conserved α+β core domain and an auxiliary C-terminal treble-clef zinc finger.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944229Structure of a tryptophanyl-tRNA synthetase containing an iron-sulfur cluster.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944228The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944225Structure of a membrane-attack complex/perforin (MACPF) family protein from the human gut symbiont Bacteroides thetaiotaomicron.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944224Structure of Bacteroides thetaiotaomicron BT2081 at 2.05⿿ÿ resolution: the first structural representative of a new protein family that may play a role in carbohydrate metabolism.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944223A conserved fold for fimbrial components revealed by the crystal structure of a putative fimbrial assembly protein (BT1062) from Bacteroides thetaiotaomicron at 2.2⿿ÿ resolution.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944222Structure of BT_3984, a member of the SusD/RagB family of nutrient-binding molecules.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944221The structure of BVU2987 from Bacteroides vulgatus reveals a superfamily of bacterial periplasmic proteins with possible inhibitory function.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944219The structure of KPN03535 (gi|152972051), a novel putative lipoprotein from Klebsiella pneumoniae, reveals an OB-fold.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944218Open and closed conformations of two SpoIIAA-like proteins (YP_749275.1 and YP_001095227.1) provide insights into membrane association and ligand binding.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944217Structure of a putative NTP pyrophosphohydrolase: YP_001813558.1 from Exiguobacterium sibiricum 255-15.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944216Structure of an essential bacterial protein YeaZ (TM0874) from Thermotoga maritima at 2.5⿿ÿ resolution.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944214Structures of the first representatives of Pfam family PF06938 (DUF1285) reveal a new fold with repeated structural motifs and possible involvement in signal transduction.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944213The structure of the first representative of Pfam family PF06475 reveals a new fold with possible involvement in glycolipid metabolism.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944212Structure of LP2179, the first representative of Pfam family PF08866, suggests a new fold with a role in amino-acid metabolism.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944211The structure of Jann_2411 (DUF1470) from Jannaschia sp. at 1.45⿿ÿ resolution reveals a new fold (the ABATE domain) and suggests its possible role as a transcription regulator.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944209Structures of the first representatives of Pfam family PF06684 (DUF1185) reveal a novel variant of the Bacillus chorismate mutase fold and suggest a role in amino-acid metabolism.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944208The structure of the first representative of Pfam family PF09836 reveals a two-domain organization and suggests involvement in transcriptional regulation.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944207Structure of the first representative of Pfam family PF04016 (DUF364) reveals enolase and Rossmann-like folds that combine to form a unique active site with a possible role in heavy-metal chelation.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944206The structure of SSO2064, the first representative of Pfam family PF01796, reveals a novel two-domain zinc-ribbon OB-fold architecture with a potential acyl-CoA-binding role.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20944205Structure of the first representative of Pfam family PF09410 (DUF2006) reveals a structural signature of the calycin superfamily that suggests a role in lipid metabolism.Acta Crystallogr Sect F Struct Biol Cryst Commun2010
20122942Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair.J Mol Biol2010
19000695A structural basis for the regulatory inactivation of DnaA.J Mol Biol2009
19678698Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework.ACS Chem Biol2009
19450606Crystal structure of histidine phosphotransfer protein ShpA, an essential regulator of stalk biogenesis in Caulobacter crescentus.J Mol Biol2009
19567872Structural and functional characterizations of SsgB, a conserved activator of developmental cell division in morphologically complex actinomycetes.J Biol Chem2009
19089981Crystal structure of a novel archaeal AAA+ ATPase SSO1545 from Sulfolobus solfataricus.Proteins2009
19173316Crystal structure of a novel Sm-like protein of putative cyanophage origin at 2.60 A resolution.Proteins2009
19127588Crystal structure of the Fic (Filamentation induced by cAMP) family protein SO4266 (gi|24375750) from Shewanella oneidensis MR-1 at 1.6 A resolution.Proteins2009
19217401Structural basis of murein peptide specificity of a gamma-D-glutamyl-l-diamino acid endopeptidase.Structure2009
19246004Thiopeptide biosynthesis featuring ribosomally synthesized precursor peptides and conserved posttranslational modifications.Chem Biol2009
18275082Crystal structure of an ADP-ribosylated protein with a cytidine deaminase-like fold, but unknown function (TM1506), from Thermotoga maritima at 2.70 A resolution.Proteins2008
18260100Crystal structure of AICAR transformylase IMP cyclohydrolase (TM1249) from Thermotoga maritima at 1.88 A resolution.Proteins2008
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Collaborators

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University of California Riverside
Co-authored papers 46
University of California
Co-authored papers 46
Stanford University
Co-authored papers 46
Argonne National Laboratory
Co-authored papers 46
Joint Center for Structural Genomics
Co-authored papers 46
Merck & Co., Inc.
Co-authored papers 46
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The Scripps Research Institute, USA The Skaggs Institute for Chemical Biology
Co-authored papers 46
University of California San Francisco
Co-authored papers 46
Joint Center for Structural Genomics
Co-authored papers 46
Accelero Biostructures Inc., USA XPose Therapeutics Inc.
Co-authored papers 46
Regeneron Pharmaceuticals, Inc.
Co-authored papers 46
Genomics Institute of the Novartis Research Foundation
Co-authored papers 46
Merck & Co., Inc.
Co-authored papers 46
University of California Riverside School of Medicine
Co-authored papers 46
Institute of Science, Banaras Hindu University
Co-authored papers 45
Cardiovascular Institute, Stanford University School of Medicine
Co-authored papers 45
Celgene/Bristol-Myers Squibb Corporation
Co-authored papers 45
Joint Center for Structural Genomics
Co-authored papers 44
Co-authored papers 44
Bridge Institute, University of Southern California
Co-authored papers 44
Genomics Institute of the Novartis Research Foundation
Co-authored papers 43
Joint Center for Structural Genomics, University of California - San Diego
Co-authored papers 43
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Joint Center for Structural Genomics
Co-authored papers 42
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The Joint Center for Structural Genomics, Stanford University
Co-authored papers 39
Joint Center for Structural Genomics, Sanford-Burnham Medical Research Institute
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