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Author Details

Kenneth W Mahaffey
Stanford University Medical School
1992
601
104
PMIDPaper TitleJournal TitlePublished Year
37881140Timing of statistical benefit of canagliflozin in patients with type 2 diabetes for cardiovascular and heart failure outcomes: Insights from the CANVAS Program and CREDENCE trial.Diabetes Obes Metab2024
37749420Training New DMC Members: A Call to Action.Ther Innov Regul Sci2024
37952217Estimated Lifetime Cardiovascular, Kidney, and Mortality Benefits of Combination Treatment With SGLT2 Inhibitors, GLP-1 Receptor Agonists, and Nonsteroidal MRA Compared With Conventional Care in Patients With Type 2 Diabetes and Albuminuria.Circulation2024
37950739Innovation in Event Adjudication-Human vs Machine.JAMA Cardiol2024
37844669Treatment effect of canagliflozin for patients on therapy for heart failure: Pooled analysis of the CANVAS program and CREDENCE trial.Int J Cardiol2024
36342828Randomized Clinical Trial to Evaluate an Atrial Fibrillation Stroke Prevention Shared Decision-Making Pathway.J Am Heart Assoc2023
37596725Predictors of intracranial hemorrhage in patients with atrial fibrillation treated with oral anticoagulants: Insights from the GARFIELD-AF and ORBIT-AF registries.Clin Cardiol2023
37745930The evolving role of data & safety monitoring boards for real-world clinical trials.J Clin Transl Sci2023
37876229Effect of SGLT2 Inhibitors on Discontinuation of Renin-angiotensin System Blockade: A Joint Analysis of the CREDENCE and DAPA-CKD Trials.J Am Soc Nephrol2023
37120538Extremes of both weight gain and weight loss are associated with increased incidence of heart failure and cardiovascular death: evidence from the CANVAS Program and CREDENCE.Cardiovasc Diabetol2023
37345834Canagliflozin, Blood Pressure Variability, and Risk of Cardiovascular, Kidney, and Mortality Outcomes: Pooled Individual Participant Data From the CANVAS and CREDENCE Trials.J Am Heart Assoc2023
37116641Clinical and Echocardiographic Diversity Associated With Physical Fitness in the Project Baseline Health Study: Implications for Heart Failure Staging.J Card Fail2023
37311602Cardiorenal protective effects of canagliflozin in CREDENCE according to glucose lowering.BMJ Open Diabetes Res Care2023
36974373Effects of canagliflozin on cardiovascular and kidney events in patients with chronic kidney disease with and without peripheral arterial disease: Integrated analysis from the CANVAS Program and CREDENCE trial.Diabetes Obes Metab2023
37039013Accelerated Epigenetic Aging Is Associated With Multiple Cardiometabolic, Hematologic, and Renal Abnormalities: A Project Baseline Health Substudy.Circ Genom Precis Med2023
36999981Glycemic Control and Effects of Canagliflozin in Reducing Albuminuria and eGFR: A Post Hoc Analysis of the CREDENCE Trial.Clin J Am Soc Nephrol2023
37161691The sodium-glucose cotransporter-2 inhibitor canagliflozin does not increase risk of non-genital skin and soft tissue infections in people with type 2 diabetes mellitus: A pooled post hoc analysis from the CANVAS Program and CREDENCE randomized double-blind trials.Diabetes Obes Metab2023
36889425Kidney and Cardiovascular Effects of Canagliflozin According to Age and Sex: A Post Hoc Analysis of the CREDENCE Randomized Clinical Trial.Am J Kidney Dis2023
36751465Design and development of a digital shared decision-making tool for stroke prevention in atrial fibrillation.JAMIA Open2023
36655422Effects of canagliflozin on liver steatosis and fibrosis markers in patients with type 2 diabetes and chronic kidney disease: A post hoc analysis of the CREDENCE trial.Diabetes Obes Metab2023
36651820The rationale, design and baseline data of FLOW, a kidney outcomes trial with once-weekly semaglutide in people with type 2 diabetes and chronic kidney disease.Nephrol Dial Transplant2023
36942888Cardiovascular and kidney outcomes with canagliflozin according to type 2 diabetes treatment targets at baseline: Data from the CANVAS programme and CREDENCE.Diabetes Obes Metab2023
34331235Cost-Consequence Analysis of Using Cangrelor in High Angiographic Risk Percutaneous Coronary Intervention Patients: A US Hospital Perspective.Am J Cardiovasc Drugs2022
35677742Risk Factors for Fracture in Patients with Coexisting Chronic Kidney Disease and Type 2 Diabetes: An Observational Analysis from the CREDENCE Trial.J Diabetes Res2022
35737275Cardiovascular and Renal Outcomes with Finerenone, a Selective Mineralocorticoid Receptor Antagonist.Cardiol Ther2022
35835600Outcomes After Acute Coronary Syndrome in Patients With Diabetes Mellitus and Peripheral Artery Disease (from the TRACER, TRILOGY-ACS, APPRAISE-2, and PLATO Clinical Trials).Am J Cardiol2022
35764796Pandemic-proof recruitment and engagement in a fully decentralized trial in atrial fibrillation patients (DeTAP).NPJ Digit Med2022
35724306Fasting Substrate Concentrations Predict Cardiovascular Outcomes in the CANagliflozin cardioVascular Assessment Study (CANVAS).Diabetes Care2022
35394821Sodium-Glucose Cotransporter 2 Inhibitors and Risk of Hyperkalemia in People With Type 2 Diabetes: A Meta-Analysis of Individual Participant Data From Randomized, Controlled Trials.Circulation2022
35695137Lessons learned in the Apple Heart Study and implications for the data management of future digital clinical trials.J Biopharm Stat2022
35621222Total Cardiovascular and Limb Events and the Impact of Polyvascular Disease in Chronic Symptomatic Peripheral Artery Disease.J Am Heart Assoc2022
35589614Canagliflozin and atrial fibrillation in type 2 diabetes mellitus: A secondary analysis from the CANVAS Program and CREDENCE trial and meta-analysis.Diabetes Obes Metab2022
35483761Impact of Polyvascular Disease and Diabetes on Limb and Cardiovascular Risk in Peripheral Artery Disease.J Am Coll Cardiol2022
35850765Multi-dimensional characterization of prediabetes in the Project Baseline Health Study.Cardiovasc Diabetol2022
36589778The development of a mobile app-focused deduplication strategy for the Apple Heart Study that informs recommendations for future digital trials.Stat (Int Stat Inst)2022
35872137Association of left ventricular diastolic function with coronary artery calcium score: A Project Baseline Health Study.J Cardiovasc Comput Tomogr2022
36245651A <i>Post Hoc</i> Analysis of KidneyIntelX and Cardiorenal Outcomes in Diabetic Kidney Disease.Kidney3602022
35938182Canagliflozin, mental health adverse events and diabetes: Exploratory analysis of the CREDENCE trial and CANVAS Program.Diabetes Obes Metab2022
36335914Apixaban for Patients With Atrial Fibrillation on Hemodialysis: A Multicenter Randomized Controlled Trial.Circulation2022
35929472Effect of Canagliflozin on Total Cardiovascular Burden in Patients With Diabetes and Chronic Kidney Disease: A Post Hoc Analysis From the CREDENCE Trial.J Am Heart Assoc2022
36302586Biomarker-Based Prediction of Recurrent Ischemic Events in Patients With Acute Coronary Syndromes.J Am Coll Cardiol2022
36302584Cardiovascular Effects of Canagliflozin in Relation to Renal Function and Albuminuria.J Am Coll Cardiol2022
35928933Understanding Study Drug Discontinuation Through EUCLID.Front Cardiovasc Med2022
36151557Initiation of the SGLT2 inhibitor canagliflozin to prevent kidney and heart failure outcomes guided by HbA1c, albuminuria, and predicted risk of kidney failure.Cardiovasc Diabetol2022
33826709Effects of canagliflozin on myocardial infarction: a post hoc analysis of the CANVAS programme and CREDENCE trial.Cardiovasc Res2022
35016188Clinical Utility of KidneyIntelX in Early Stages of Diabetic Kidney Disease in the CANVAS Trial.Am J Nephrol2022
34985309Direct Oral Anticoagulants Versus Warfarin in Patients With Atrial Fibrillation: Patient-Level Network Meta-Analyses of Randomized Clinical Trials With Interaction Testing by Age and Sex.Circulation2022
34915723Ischemic Events Occur Early in Patients Undergoing Percutaneous Coronary Intervention and Are Reduced With Cangrelor: Findings From CHAMPION PHOENIX.Circ Cardiovasc Interv2022
35092723The ENHANCE-AF clinical trial to evaluate an atrial fibrillation shared decision-making pathway: Rationale and study design.Am Heart J2022
34973948Clinical events classification (CEC) in clinical trials: Report on the current landscape and future directions - proceedings from the CEC Summit 2018.Am Heart J2022
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Collaborators

Co-authored papers 132
Duke University, NC Duke Clinical Research Institute
Co-authored papers 130
From the National Institutes of Health
Co-authored papers 110
Duke Clinical Research Institute
Co-authored papers 92
Clinical Epidemiology Unit, Massachusetts General Hospital
Co-authored papers 90
University of Texas Southwestern Medical Center
Co-authored papers 87
David Geffen School of Medicine, University of California, Los Angeles Medical Center
Co-authored papers 75
Mayo Clinic College of Medicine and Science
Co-authored papers 67
Co-authored papers 61
Duke Clinical Research Institute, Duke University
Co-authored papers 58
Icahn School of Medicine at Mount Sinai Health System
Co-authored papers 53
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Duke Clinical Research Institute, Duke University
Co-authored papers 45
Brigham and Women's Hospital
Co-authored papers 40
Duke University Medical Center
Co-authored papers 34
University of Utah Health Sciences Center
Co-authored papers 33
Kaiser Permanente Northern California
Co-authored papers 32
Duke University Medical Center-Duke Clinical Research Institute
Co-authored papers 29
Universidade Federal de Sao Paulo
Co-authored papers 26
Co-authored papers 25
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Mount Sinai Hospital, University of Toronto
Co-authored papers 16
Stanford University
Co-authored papers 12
Co-authored papers 12
Stanford University School of Medicine
Co-authored papers 11
Hennepin Healthcare/University of Minnesota
Co-authored papers 10
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Thomas Jefferson University Hospital, Pennsylvania Sidney Kimmel Medical College
Co-authored papers 9
Stanford University School of Medicine
Co-authored papers 9