| 36068482 | The Opioid Epidemic: a Crisis Disproportionately Impacting Black Americans and Urban Communities. | J Racial Ethn Health Disparities | 2023 |
| 36596894 | NIAID workshop on T cell technologies. | Nat Immunol | 2023 |
| 35332332 | Systematic identification of biomarker-driven drug combinations to overcome resistance. | Nat Chem Biol | 2022 |
| 34272366 | Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase. | Nat Commun | 2021 |
| 33246941 | Correction: Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12. | J Biol Chem | 2020 |
| 32005668 | Mechanistic insights into cancer cell killing through interaction of phosphodiesterase 3A and schlafen family member 12. | J Biol Chem | 2020 |
| 30789961 | Casting a wider net: Immunosurveillance by nonclassical MHC molecules. | PLoS Pathog | 2019 |
| 31749907 | Optimization of PDE3A Modulators for SLFN12-Dependent Cancer Cell Killing. | ACS Med Chem Lett | 2019 |
| 30880155 | Stabilization of the Max Homodimer with a Small Molecule Attenuates Myc-Driven Transcription. | Cell Chem Biol | 2019 |
| 29153505 | Structural Basis for the Inhibitory Effects of Ubistatins in the Ubiquitin-Proteasome Pathway. | Structure | 2017 |
| 27064299 | Inhibition of Zinc-Dependent Histone Deacetylases with a Chemically Triggered Electrophile. | ACS Chem Biol | 2016 |
| 26656089 | Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics. | Nat Chem Biol | 2016 |
| 27641501 | Inhibition of Dihydroorotate Dehydrogenase Overcomes Differentiation Blockade in Acute Myeloid Leukemia. | Cell | 2016 |
| 27694802 | Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells. | Nat Chem Biol | 2016 |
| 27602946 | Diversity-oriented synthesis yields novel multistage antimalarial inhibitors. | Nature | 2016 |
| 27994748 | Development of ML390: A Human DHODH Inhibitor That Induces Differentiation in Acute Myeloid Leukemia. | ACS Med Chem Lett | 2016 |
| 26314865 | Chemical perturbation of an intrinsically disordered region of TFIID distinguishes two modes of transcription initiation. | Elife | 2015 |
| 26478787 | Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport. | ACS Med Chem Lett | 2015 |
| 24737027 | A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein. | Mol Cancer Ther | 2014 |
| 25454272 | Dilazep analogues for the study of equilibrative nucleoside transporters 1 and 2 (ENT1 and ENT2). | Bioorg Med Chem Lett | 2014 |
| 23562243 | Discovery of a small-molecule inhibitor and cellular probe of Keap1-Nrf2 protein-protein interaction. | Bioorg Med Chem Lett | 2013 |
| 22297109 | Development of small-molecule probes that selectively kill cells induced to express mutant RAS. | Bioorg Med Chem Lett | 2012 |
| 23074541 | Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies. | ACS Med Chem Lett | 2012 |
| 22726680 | Inhibition of histone deacetylase 3 protects beta cells from cytokine-induced apoptosis. | Chem Biol | 2012 |
| 22863010 | Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL. | Cell | 2012 |
| 22503247 | Identification of a selective small molecule inhibitor of breast cancer stem cells. | Bioorg Med Chem Lett | 2012 |
| 22434908 | Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells. | Proc Natl Acad Sci U S A | 2012 |
| 20123131 | Hematopoietic cell types: prototype for a revised cell ontology. | J Biomed Inform | 2011 |
| 21802010 | AAK1 identified as an inhibitor of neuregulin-1/ErbB4-dependent neurotrophic factor signaling using integrative chemical genomics and proteomics. | Chem Biol | 2011 |
| 21907926 | Rho kinase regulates the survival and transformation of cells bearing oncogenic forms of KIT, FLT3, and BCR-ABL. | Cancer Cell | 2011 |
| 21555567 | Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress. | Proc Natl Acad Sci U S A | 2011 |
| 21209116 | Roscovitine inhibits EBNA1 serine 393 phosphorylation, nuclear localization, transcription, and episome maintenance. | J Virol | 2011 |
| 20028085 | Binding affinity and kinetic analysis of targeted small molecule-modified nanoparticles. | Bioconjug Chem | 2010 |
| 21874153 | Effect of Inhibiting Histone Deacetylase with Short-Chain Carboxylic Acids and Their Hydroxamic Acid Analogs on Vertebrate Development and Neuronal Chromatin. | ACS Med Chem Lett | 2010 |
| 20550176 | Small-Molecule Suppressors of Cytokine-Induced beta-Cell Apoptosis. | ACS Chem Biol | 2010 |
| 20126263 | A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint. | PLoS Biol | 2010 |
| 19098899 | Bead-based profiling of tyrosine kinase phosphorylation identifies SRC as a potential target for glioblastoma therapy. | Nat Biotechnol | 2009 |
| 18285338 | Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity. | J Biol Chem | 2008 |
| 17486044 | Small molecules enhance autophagy and reduce toxicity in Huntington's disease models. | Nat Chem Biol | 2007 |
| 17348730 | Ring-opening and ring-closing reactions of a shikimic acid-derived substrate leading to diverse small molecules. | J Comb Chem | 2007 |
| 17467987 | Discovery of new C3aR ligands. Part 1: arginine derivatives. | Bioorg Med Chem Lett | 2007 |
| 16982730 | Small molecules, big players: the National Cancer Institute's Initiative for Chemical Genetics. | Cancer Res | 2006 |
| 15686917 | 5-Lipoxygenase inhibition by N-hydroxycarbamates in dual-function compounds. | Bioorg Med Chem Lett | 2005 |
| 15966769 | Animal models for radiation injury, protection and therapy. | Radiat Res | 2005 |
| 15054606 | Novel dual acting molecules possessing 5-lipoxygenase enzyme inhibition and histamine H(1) receptor antagonist properties. | Inflamm Res | 2004 |
| 15482930 | Cetirizine and loratadine-based antihistamines with 5-lipoxygenase inhibitory activity. | Bioorg Med Chem Lett | 2004 |
| 15081022 | 5-lipoxygenase inhibitors with histamine H(1) receptor antagonist activity. | Bioorg Med Chem Lett | 2004 |
| 12517956 | Lipid raft-independent B cell receptor-mediated antigen internalization and intracellular trafficking. | J Immunol | 2003 |
| 12639818 | Gallium arsenide exposure impairs splenic B cell accessory function. | Int Immunopharmacol | 2003 |
| 11359820 | Prolonged antigen persistence within nonterminal late endocytic compartments of antigen-specific B lymphocytes. | J Immunol | 2001 |