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Author Details

Leena Latonen
Foundation for the Finnish Cancer Institute
1999
64
24
PMIDPaper TitleJournal TitlePublished Year
36801642Unstained Tissue Imaging and Virtual Hematoxylin and Eosin Staining of Histologic Whole Slide Images.Lab Invest2023
37591798Complementary analysis of proteome-wide proteomics reveals changes in RNA binding protein-profiles during prostate cancer progression.Cancer Rep (Hoboken)2023
37652005Deep learning transforms colorectal cancer biomarker prediction from histopathology images.Cancer Cell2023
37140987Identification of long noncoding RNAs with aberrant expression in prostate cancer metastases.Endocr Relat Cancer2023
37223268The effect of neural network architecture on virtual H&E staining: Systematic assessment of histological feasibility.Patterns (N Y)2023
35228520miR-32 promotes MYC-driven prostate cancer.Oncogenesis2022
36299481Nuclear size rectification: A potential new therapeutic approach to reduce metastasis in cancer.Front Cell Dev Biol2022
36348119Nuclear Organization in Response to Stress: A Special Focus on Nucleoli.Results Probl Cell Differ2022
36219867Nonmalignant AR-positive prostate epithelial cells and cancer cells respond differently to androgen.Endocr Relat Cancer2022
35128089Spatial analysis of histology in 3D: quantification and visualization of organ and tumor level tissue environment.Heliyon2022
35199530Chemical Interrogation of Nuclear Size Identifies Compounds with Cancer Cell Line-Specific Effects on Migration and Invasion.ACS Chem Biol2022
34686173Virtual reality for 3D histology: multi-scale visualization of organs with interactive feature exploration.BMC Cancer2021
33670112Convolutional Neural Network-Based Artificial Intelligence for Classification of Protein Localization Patterns.Biomolecules2021
33892405Building a central repository landmarks a new era for artificial intelligence-assisted digital pathology development in Europe.Eur J Cancer2021
33932111Expression and ERG regulation of PIM kinases in prostate cancer.Cancer Med2021
33634124Androgen-Driven Fusion Genes and Chimeric Transcripts in Prostate Cancer.Front Cell Dev Biol2021
34638309Proteomic Landscape of Prostate Cancer: The View Provided by Quantitative Proteomics, Integrative Analyses, and Protein Interactomes.Cancers (Basel)2021
34396389A systematic comparison of data- and knowledge-driven approaches to disease subtype discovery.Brief Bioinform2021
32275587ANHIR: Automatic Non-Rigid Histological Image Registration Challenge.IEEE Trans Med Imaging2020
32555329AR and ERG drive the expression of prostate cancer specific long noncoding RNAs.Oncogene2020
31080406Phase-to-Phase With Nucleoli - Stress Responses, Protein Aggregation and Novel Roles of RNA.Front Cell Neurosci2019
31730483Phosphorylation of NFATC1 at PIM1 target sites is essential for its ability to promote prostate cancer cell migration and invasion.Cell Commun Signal2019
319464903D-Printed Whole Prostate Models with Tumor Hotspots Using Dual-Extruder Printer.Annu Int Conf IEEE Eng Med Biol Soc2019
30767778Iterative unsupervised domain adaptation for generalized cell detection from brightfield z-stacks.BMC Bioinformatics2019
29563510Integrative proteomics in prostate cancer uncovers robustness against genomic and transcriptomic aberrations during disease progression.Nat Commun2018
30234142Proteomics of prostate cancer - revealing how cancer cells master their messy genomes.Oncoscience2018
29988112Constitutively active androgen receptor splice variants AR-V3, AR-V7 and AR-V9 are co-expressed in castration-resistant prostate cancer metastases.Br J Cancer2018
29684099Comparative analysis of tissue reconstruction algorithms for 3D histology.Bioinformatics2018
28827140In Vivo Expression of miR-32 Induces Proliferation in Prostate Epithelium.Am J Pathol2017
28426134Metastasis detection from whole slide images using local features and random forests.Cytometry A2017
28317907Analysis of spatial heterogeneity in normal epithelium and preneoplastic alterations in mouse prostate tumor models.Sci Rep2017
29234806Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer.JAMA2017
27074291Amplification of the 9p13.3 chromosomal region in prostate cancer.Genes Chromosomes Cancer2016
27538859Incidence of Mucinous Metaplasia in the Prostate of FVB/N Mice (Mus musculus).Comp Med2016
27246339Measuring the Expression of microRNAs Regulated by Androgens.Methods Mol Biol2016
26955503Feature-based analysis of mouse prostatic intraepithelial neoplasia in histological tissue sections.J Pathol Inform2016
27081305Flow Cytometry-Based Classification in Cancer Research: A View on Feature Selection.Cancer Inform2016
25749039Recurrent SKIL-activating rearrangements in ETS-negative prostate cancer.Oncotarget2015
26282172Transcriptome Sequencing Reveals PCAT5 as a Novel ERG-Regulated Long Noncoding RNA in Prostate Cancer.Cancer Res2015
26129688Epigenetically altered miR-193b targets cyclin D1 in prostate cancer.Cancer Med2015
25965834CIP2A is a candidate therapeutic target in clinically challenging prostate cancer cell populations.Oncotarget2015
21882188Cysteine-rich protein 1 is regulated by transforming growth factor-β1 and expressed in lung fibrosis.J Cell Physiol2012
22266859Androgen-regulated miR-32 targets BTG2 and is overexpressed in castration-resistant prostate cancer.Oncogene2012
21909140Overexpression of androgen receptor enhances the binding of the receptor to the chromatin in prostate cancer.Oncogene2012
20956947Proteasome inhibitors induce nucleolar aggregation of proteasome target proteins and polyadenylated RNA by altering ubiquitin availability.Oncogene2011
22028916Contribution of ARLTS1 Cys148Arg (T442C) variant with prostate cancer risk and ARLTS1 function in prostate cancer cells.PLoS One2011
21778410Quantitative proteomics and dynamic imaging of the nucleolus reveal distinct responses to UV and ionizing radiation.Mol Cell Proteomics2011
21425306Nucleolar aggresomes as counterparts of cytoplasmic aggresomes in proteotoxic stress. Proteasome inhibitors induce nuclear ribonucleoprotein inclusions that accumulate several key factors of neurodegenerative diseases and cancer.Bioessays2011
20945501Androgen regulation of micro-RNAs in prostate cancer.Prostate2011
20415737Ultraviolet B radiation regulates cysteine-rich protein 1 in human keratinocytes.Photodermatol Photoimmunol Photomed2010
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Collaborators

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Co-authored papers 25
Institute of Biomedicine, University of Turku
Co-authored papers 20
Prostate Cancer Research Center, Tampere University and Tays Cancer Center
Co-authored papers 14
Karolinska Institutet
Co-authored papers 9
Tampere University
Co-authored papers 7
University of British Columbia
Co-authored papers 6
Tampere University
Co-authored papers 6
University of Washington
Co-authored papers 5
Northwestern University Feinberg School of Medicine Chicago
Co-authored papers 5
Prostate Cancer Research Center, Tampere University and Tays Cancer Center
Co-authored papers 2
The Brady Urological Institute, The Johns Hopkins School of Medicine
Co-authored papers 2
University of Manchester
Co-authored papers 2
Karolinska Institute
Co-authored papers 2
Hospital Clinico Universitario "Lozano Blesa"
Co-authored papers 2
Radboud University Medical Center
Co-authored papers 1
University of Castilla-La Mancha
Co-authored papers 1
University Medical Center Utrecht
Co-authored papers 1
Massachusetts General Hospital, Harvard University
Co-authored papers 1
NLP Logix LLC
Co-authored papers 1
Huazhong Agricultural University
Co-authored papers 1
Sorbonne University, Pierre and Marie Curie University
Co-authored papers 1
California State University
Co-authored papers 1
Technical University of Munich
Co-authored papers 1
Western Sydney University
Co-authored papers 1
Alrijne Hospital Leiderdorp
Co-authored papers 1
Beth Israel Deaconess Medical Center, Harvard Medical School
Co-authored papers 1
Center for Mind/Brain Sciences
Co-authored papers 1
Kansai University
Co-authored papers 1
Centre de Recherche du Centre Hospitalier Universitaire de Sherbrooke (CRCHUS)
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Radboud University Medical Center
Co-authored papers 1