|
| 34385484 | NOTUM promotes thermogenic capacity and protects against diet-induced obesity in male mice. | Scientific Reports | 2021 |
| 34233476 | Genome-Wide Association Study Identifies a Functional Variant Associated With HDL-C (High-Density Lipoprotein Cholesterol) Levels and Premature Coronary Artery Disease. | Arteriosclerosis, Thrombosis, and Vascular Biology | 2021 |
| 33665512 | Loop Diuretics Inhibit Renal Excretion of Trimethylamine -Oxide. | JACC: Basic to Translational Science | 2021 |
| 33436815 | Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice. | Sci Rep | 2021 |
| 33086870 | Local M-CSF (Macrophage Colony-Stimulating Factor) Expression Regulates Macrophage Proliferation and Apoptosis in Atherosclerosis. | Arteriosclerosis, Thrombosis, and Vascular Biology | 2021 |
| 32791310 | Trimethylamine N-oxide levels are associated with NASH in obese subjects with type 2 diabetes. | | 2021 |
| 33033318 | Suppression of inflammatory arthritis in human serum paraoxonase 1 transgenic mice. | Scientific Reports | 2020 |
| 31340670 | Diesel Exhaust Induces Mitochondrial Dysfunction, Hyperlipidemia, and Liver Steatosis. | Arteriosclerosis, Thrombosis, and Vascular Biology | 2019 |
| 30641857 | PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity. | Antioxidants | 2019 |
| 31070450 | Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report. | Arteriosclerosis, Thrombosis, and Vascular Biology | 2019 |
| 29729330 | Paraoxonase 2 prevents the development of heart failure. | Free Radic Biol Med | 2018 |
| 29981269 | Flavin monooxygenase 3, the host hepatic enzyme in the metaorganismal trimethylamine N-oxide-generating pathway, modulates platelet responsiveness and thrombosis risk. | Journal of Thrombosis and Haemostasis | 2018 |
| 30241945 | Identification of biologically active δ-lactone eicosanoids as paraoxonase substrates. | Biochemical and Biophysical Research Communications | 2018 |
| 29719227 | A Strategy for Discovery of Endocrine Interactions with Application to Whole-Body Metabolism. | Cell Metab | 2018 |
| 28636934 | The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue. | Cell Rep | 2017 |
| 28683320 | The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue. | Cell Rep | 2017 |
| 26903003 | Trimethylamine N-Oxide Promotes Vascular Inflammation Through Signaling of Mitogen-Activated Protein Kinase and Nuclear Factor-κB. | Journal of the American Heart Association | 2016 |
| 25600868 | The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance. | Cell Reports | 2015 |
| 25378658 | Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis. | Journal of Lipid Research | 2015 |
| 25477283 | PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis. | FASEB Journal | 2015 |
| 24860088 | Genetic regulation of mouse liver metabolite levels. | Molecular Systems Biology | 2014 |
| 24415945 | Meta-analysis identifies gene-by-environment interactions as demonstrated in a study of 4,965 mice. | PLoS Genetics | 2014 |
| 25038992 | Inflammation, infection, cancer and all that⿦the role of paraoxonases. | Advances in Experimental Medicine and Biology | 2014 |
| 23448543 | Paraoxonase-1 deficiency is associated with severe liver steatosis in mice fed a high-fat high-cholesterol diet: a metabolomic approach. | Journal of Proteome Research | 2013 |
| 23908111 | Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex. | Journal of Clinical Investigation | 2013 |
| 23766557 | Paraoxonase-1 inhibits oxidized low-density lipoprotein-induced metabolic alterations and apoptosis in endothelial cells: a nondirected metabolomic study. | Mediators of Inflammation | 2013 |
| 23752203 | Hyodeoxycholic acid improves HDL function and inhibits atherosclerotic lesion formation in LDLR-knockout mice. | FASEB Journal | 2013 |
| 23312283 | Trimethylamine-N-oxide, a metabolite associated with atherosclerosis, exhibits complex genetic and dietary regulation. | | 2013 |
| 23625949 | Response to Pomozi et al's research commentary. | Circ Res | 2013 |
| 23291186 | Role of paraoxonase-1 in bone anabolic effects of parathyroid hormone in hyperlipidemic mice. | Biochemical and Biophysical Research Communications | 2013 |
| 22441669 | PON3 is upregulated in cancer tissues and protects against mitochondrial superoxide-mediated cell death. | Cell Death and Differentiation | 2012 |
| 22811557 | ABCC6 localizes to the mitochondria-associated membrane. | Circ Res | 2012 |
| 22406444 | Metabolism and neurotoxicity of homocysteine thiolactone in mice: evidence for a protective role of paraoxonase 1. | Journal of Alzheimer's Disease | 2012 |
| 21900915 | Paraoxonase-1 and clopidogrel efficacy. | Nature Medicine | 2011 |
| 21836061 | Paraoxonase-2 modulates stress response of endothelial cells to oxidized phospholipids and a bacterial quorum-sensing molecule. | Arteriosclerosis, Thrombosis, and Vascular Biology | 2011 |
| 21701070 | Mechanisms underlying adverse effects of HDL on eNOS-activating pathways in patients with coronary artery disease. | Journal of Clinical Investigation | 2011 |
| 20221872 | Temporal and tissue-specific patterns of Pon3 expression in mouse: in situ hybridization analysis. | Advances in Experimental Medicine and Biology | 2010 |
| 19840942 | A common mutation in paraoxonase-2 results in impaired lactonase activity. | Journal of Biological Chemistry | 2009 |
| 19204075 | Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice. | FASEB J | 2009 |
| 19474728 | The roles of PON1 and PON2 in cardiovascular disease and innate immunity. | Current Opinion in Lipidology | 2009 |
| 18607188 | Is it just paraoxonase 1 or are other members of the paraoxonase gene family implicated in atherosclerosis? | Current Opinion in Lipidology | 2008 |
| 18258604 | Cells deficient in oxidative DNA damage repair genes Myh and Ogg1 are sensitive to oxidants with increased G2/M arrest and multinucleation. | Carcinogenesis | 2008 |
| 17122353 | Paraoxonase-2 deficiency enhances Pseudomonas aeruginosa quorum sensing in murine tracheal epithelia. | American Journal of Physiology - Lung Cellular and Molecular Physiology | 2007 |
| 17379834 | Decreased obesity and atherosclerosis in human paraoxonase 3 transgenic mice. | Circulation Research | 2007 |
| 17994087 | Evolution of genes and genomes on the Drosophila phylogeny. | Nature | 2007 |
| 17327360 | Mutations in methylenetetrahydrofolate reductase or cystathionine beta-synthase gene, or a high-methionine diet, increase homocysteine thiolactone levels in humans and mice. | FASEB Journal | 2007 |
| 17785681 | FK506, a calcineurin inhibitor, prevents cadmium-induced testicular toxicity in mice. | Toxicol Sci | 2007 |
| 17495224 | Heme oxygenase-1 expression in macrophages plays a beneficial role in atherosclerosis. | Circulation Research | 2007 |
| 17446441 | Adenovirus-mediated expression of human paraoxonase 3 protects against the progression of atherosclerosis in apolipoprotein E-deficient mice. | Arteriosclerosis, Thrombosis, and Vascular Biology | 2007 |
| 16269825 | A role for FXR and human FGF-19 in the repression of paraoxonase-1 gene expression by bile acids. | Journal of Lipid Research | 2006 |