Author details

Full Name

Johannes Kettunen

Affiliation

ORCID

Career Start Year

2009

Papers

111

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
38030573	Clinical and biochemical associations of urinary metabolites: quantitative epidemiological approach on renal-cardiometabolic biomarkers.	Int J Epidemiol	2024
36658689	Cross-sectionally Calculated Metabolic Aging Does Not Relate to Longitudinal Metabolic Changes-Support for Stratified Aging Models.	J Clin Endocrinol Metab	2023
36653562	FinnGen provides genetic insights from a well-phenotyped isolated population.	Nature	2023
37285119	Genetic Risk Factors Associated With Preeclampsia and Hypertensive Disorders of Pregnancy.	JAMA Cardiol	2023
36829046	Author Correction: FinnGen provides genetic insights from a well-phenotyped isolated population.	Nature	2023
36823293	Longitudinal metabolomics of increasing body-mass index and waist-hip ratio reveals two dynamic patterns of obesity pandemic.	Int J Obes (Lond)	2023
37453363	Low and high serum IgG associates with respiratory infections in a young and working age population.		2023
34454985	Uniting biobank resources reveals novel genetic pathways modulating susceptibility for atopic dermatitis.	Journal of Allergy and Clinical Immunology	2022
35441226	Longitudinal profiling of metabolic ageing trends in two population cohorts of young adults.	Int J Epidemiol	2022
36285626	The Finnish genetic heritage in 2022 - from diagnosis to translational research.	Dis Model Mech	2022
35373831	There is always glucose in normal urine: unspecific excretion associated with serum glucose and glomerular filtration rate.	International Journal of Epidemiology	2022
35619160	Association between mitochondrial DNA haplogroups J and K, serum branched-chain amino acids and lowered capability for endurance exercise.	BMC Sports Science, Medicine and Rehabilitation	2022
34791234	Leveraging Northern European population history: novel low-frequency variants for polycystic ovary syndrome.	Human Reproduction	2022
35289444	Genetic and observational evidence: No independent role for cholesterol efflux over static high-density lipoprotein concentration measures in coronary heart disease risk assessment.	J Intern Med	2022
34475573	Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression.	Nat Genet	2021
33491305	The Role of Inflammatory Cytokines as Intermediates in the Pathway from Increased Adiposity to Disease.	Obesity (Silver Spring)	2021
34261659	Systematic evaluation of the association between hemoglobin levels and metabolic profile implicates beneficial effects of hypoxia.	Sci Adv	2021
33723592	HDL-Mediated Cholesterol Efflux Associates with Incident Kidney Disease.	Clinical Chemistry	2021
33351885	Metabolic profiling of angiopoietin-like protein 3 and 4 inhibition: a drug-target Mendelian randomization analysis.	Eur Heart J	2021
33413638	DNA methylation and lipid metabolism: an EWAS of 226 metabolic measures.	Clin Epigenetics	2021
33268560	Association of Circulating Metabolites in Plasma or Serum and Risk of Stroke: Meta-analysis From 7 Prospective Cohorts.	Neurology	2021
34847907	Genome-wide association study of periodontal pocketing in Finnish adults.	BMC Oral Health	2021
33239708	An epigenome-wide association study of metabolic syndrome and its components.	Scientific Reports	2020
32142508	Correction: Lipoprotein signatures of cholesteryl ester transfer protein and HMG-CoA reductase inhibition.	PLoS Biol	2020
32113648	Apolipoprotein A-I concentrations and risk of coronary artery disease: A Mendelian randomization study.	Atherosclerosis	2020
31943015	EpiMetal: an open-source graphical web browser tool for easy statistical analyses in epidemiology and metabolomics.	Int J Epidemiol	2020
31931463	Data-driven multivariate population subgrouping via lipoprotein phenotypes versus apolipoprotein B in the risk assessment of coronary heart disease.	Atherosclerosis	2020
30996052	Direct Estimation of HDL-Mediated Cholesterol Efflux Capacity from Serum.	Clinical Chemistry	2019
31644575	Elevated serum alpha-1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality.	PLoS ONE	2019
31584131	Circulating metabolites and the risk of type 2 diabetes: a prospective study of 11,896 young adults from four Finnish cohorts.	Diabetologia	2019
31679650	Multivariate Genome-wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy.	Am J Hum Genet	2019
31779625	Insulin resistance and systemic metabolic changes in oral glucose tolerance test in 5340 individuals: an interventional study.	BMC Medicine	2019
30422703	Associations of increased physical performance and change in body composition with molecular pathways of heart disease and diabetes risk.	American Journal of Physiology - Endocrinology and Metabolism	2019
30808802	Genome-wide meta-analysis identifies genetic locus on chromosome 9 associated with Modic changes.	Journal of Medical Genetics	2019
30689875	Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics.	Int J Epidemiol	2019
31217265	Genome-wide association study identifies seven novel loci associating with circulating cytokines and cell adhesion molecules in Finns.	J Med Genet	2019
31070104	Genetic Determinants of Circulating Glycine Levels and Risk of Coronary Artery Disease.	J Am Heart Assoc	2019
29648650	NAFLD risk alleles in PNPLA3, TM6SF2, GCKR and LYPLAL1 show divergent metabolic effects.	Hum Mol Genet	2018
30571186	Biomarker Glycoprotein Acetyls Is Associated With the Risk of a Wide Spectrum of Incident Diseases and Stratifies Mortality Risk in Angiography Patients.	Circ Genom Precis Med	2018
30524137	Metabolomic consequences of genetic inhibition of PCSK9 compared with statin treatment.	Circulation	2018
27989323	Genome-wide Association Study Identifies 27 Loci Influencing Concentrations of Circulating Cytokines and Growth Factors.	Am J Hum Genet	2017
28764798	An interaction map of circulating metabolites, immune gene networks, and their genetic regulation.	Genome Biol	2017
28615213	Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure.	J Am Heart Assoc	2017
29237677	Genome-Wide Association Study Implicates Atrial Natriuretic Peptide Rather Than B-Type Natriuretic Peptide in the Regulation of Blood Pressure in the General Population.	Circ Cardiovasc Genet	2017
27814671	Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems.	BMC Genomics	2016
27114411	Metabolic Characterization of a Rare Genetic Variation Within APOC3 and Its Lipoprotein Lipase-Independent Effects.	Circ Cardiovasc Genet	2016
27102866	Prolonged sleep restriction induces changes in pathways involved in cholesterol metabolism and inflammatory responses.	Sci Rep	2016
26965542	Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase.	J Am Coll Cardiol	2016
27005778	Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA.	Nat Commun	2016
26912228	Insomnia does not mediate or modify the association between MTNR1B risk variant rs10830963 and glucose levels.	Diabetologia	2016