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Author Details

Jennifer Cruickshank
Princess Margaret Cancer Centre, University Health Network
2000
14
11
PMIDPaper TitleJournal TitlePublished Year
37987734Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality.Cancer Res2023
35304464Biomimetic hydrogel supports initiation and growth of patient-derived breast tumor organoids.Nat Commun2022
35578032PRMT inhibition induces a viral mimicry response in triple-negative breast cancer.Nat Chem Biol2022
36280687Computational pharmacogenomic screen identifies drugs that potentiate the anti-breast cancer activity of statins.Nat Commun2022
36070391The spindle assembly checkpoint is a therapeutic vulnerability of CDK4/6 inhibitor-resistant ER<sup>+</sup> breast cancer with mitotic aberrations.Sci Adv2022
35981243Glycoproteomics Identifies Plexin-B3 as a Targetable Cell Surface Protein Required for the Growth and Invasion of Triple-Negative Breast Cancer Cells.J Proteome Res2022
34031589Mammary epithelial cells have lineage-rooted metabolic identities.Nat Metab2021
33866248Anticancer effects of radiation therapy combined with Polo-Like Kinase 4 (PLK4) inhibitor CFI-400945 in triple negative breast cancer.Breast2021
29921600Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities.J Cell Biol2018
27241552RANKL/RANK control Brca1 mutation- .Cell Res2016
23857982BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival.J Exp Med2013
20034955The N-terminus of hTERT contains a DNA-binding domain and is required for telomerase activity and cellular immortalization.Nucleic Acids Res2010
12699629Functional conservation of the telomerase protein Est1p in humans.Curr Biol2003
10801810Two domains of the epstein-barr virus origin DNA-binding protein, EBNA1, orchestrate sequence-specific DNA binding.J Biol Chem2000
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Collaborators

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Co-authored papers 7
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 6
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Co-authored papers 5
Princess Margaret Cancer Centre, University Health Network, University Ave.
Co-authored papers 4
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Co-authored papers 4
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Co-authored papers 2
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Co-authored papers 2
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Co-authored papers 2
Max Planck Institute of Biochemistry
Co-authored papers 2
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Co-authored papers 2
University of Toronto, College St
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Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 2
University of Toronto
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Margaret Cancer Center
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Princess Margaret Cancer Centre, University Health Network, University of Toronto
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Institute for Research in Immunology and Cancer, Universite de Montreal
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Ontario Institute for Cancer Research
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Beihua University
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