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Author Details

John T Loffredo
2003
30
21
PMIDPaper TitleJournal TitlePublished Year
36948922Phase 1 Study of Safety and Preliminary Clinical Activity of JNJ-63898081, a PSMA and CD3 Bispecific Antibody, for Metastatic Castration-Resistant Prostate Cancer.Clin Genitourin Cancer2023
32961119Adjuvant nivolumab versus ipilimumab in resected stage IIIB-C and stage IV melanoma (CheckMate 238): 4-year results from a multicentre, double-blind, randomised, controlled, phase 3 trial.Lancet Oncology, The2020
30530595Characterization of Mauritian Cynomolgus Macaque FcγR Alleles Using Long-Read Sequencing.Journal of Immunology2019
25585297High Reproducibility of ELISPOT Counts from Nine Different Laboratories.Cells2015
19889785Effective simian immunodeficiency virus-specific CD8+ T cells lack an easily detectable, shared characteristic.Journal of Virology2010
20686015Simian immunodeficiency virus-specific CD8+ T cells recognize Vpr- and Rev-derived epitopes early after infection.Journal of Virology2010
20812010Simian immunodeficiency virus-specific CD4+ T cells from successful vaccinees target the SIV Gag capsid.Immunogenetics2010
20219903High viremia is associated with high levels of in vivo major histocompatibility complex class I Downregulation in rhesus macaques infected with simian immunodeficiency virus SIVmac239.J Virol2010
19339351Mauritian cynomolgus macaques share two exceptionally common major histocompatibility complex class I alleles that restrict simian immunodeficiency virus-specific CD8+ T cells.J Virol2009
19494300Two MHC class I molecules associated with elite control of immunodeficiency virus replication, Mamu-B*08 and HLA-B*2705, bind peptides with sequence similarity.J Immunol2009
19403685Vaccine-induced cellular responses control simian immunodeficiency virus replication after heterologous challenge.J Virol2009
19726517Infection with "escaped" virus variants impairs control of simian immunodeficiency virus SIVmac239 replication in Mamu-B*08-positive macaques.J Virol2009
18385251Comprehensive immunological evaluation reveals surprisingly few differences between elite controller and progressor Mamu-B*17-positive simian immunodeficiency virus-infected rhesus macaques.J Virol2008
17989178The major histocompatibility complex class II alleles Mamu-DRB1*1003 and -DRB1*0306 are enriched in a cohort of simian immunodeficiency virus-infected rhesus macaque elite controllers.J Virol2008
18057253Patterns of CD8+ immunodominance may influence the ability of Mamu-B*08-positive macaques to naturally control simian immunodeficiency virus SIVmac239 replication.Journal of Virology2008
18000532CD8+ T cells from SIV elite controller macaques recognize Mamu-B*08-bound epitopes and select for widespread viral variation.PLoS One2007
17642000HIV Vaccines: from basic research to clinical trials--Keystone Symposia.IDrugs : the investigational drugs journal2007
17641886Molecular typing of major histocompatibility complex class I alleles in the Indian rhesus macaque which restrict SIV CD8+ T cell epitopes.Immunogenetics2007
17312117Gag-specific CD8+ T lymphocytes recognize infected cells before AIDS-virus integration and viral protein expression.J Immunol2007
17537848Mamu-B*08-positive macaques control simian immunodeficiency virus replication.J Virol2007
17192314The antiviral efficacy of simian immunodeficiency virus-specific CD8+ T cells is unrelated to epitope specificity and is abrogated by viral escape.Journal of Virology2007
17135324Not all cytokine-producing CD8+ T cells suppress simian immunodeficiency virus replication.Journal of Virology2007
16960778Repeated intravaginal inoculation with cell-associated simian immunodeficiency virus results in persistent infection of nonhuman primates.Journal of Infectious Diseases2006
16282500Tat(28-35)SL8-specific CD8+ T lymphocytes are more effective than Gag(181-189)CM9-specific CD8+ T lymphocytes at suppressing simian immunodeficiency virus replication in a functional in vitro assay.Journal of Virology2005
16137805A computational resource for the prediction of peptide binding to Indian rhesus macaque MHC class I molecules.Vaccine2005
15747117Characterization of the peptide-binding specificity of Mamu-A*11 results in the identification of SIV-derived epitopes and interspecies cross-reactivity.Immunogenetics2005
16306626Cytotoxic T-lymphocyte escape does not always explain the transient control of simian immunodeficiency virus SIVmac239 viremia in adenovirus-boosted and DNA-primed Mamu-A*01-positive rhesus macaques.Journal of Virology2005
16237093The high frequency Indian rhesus macaque MHC class I molecule, Mamu-B*01, does not appear to be involved in CD8+ T lymphocyte responses to SIVmac239.J Immunol2005
15470050Identification of seventeen new simian immunodeficiency virus-derived CD8+ T cell epitopes restricted by the high frequency molecule, Mamu-A*02, and potential escape from CTL recognition.J Immunol2004
12885919Major histocompatibility complex class I alleles associated with slow simian immunodeficiency virus disease progression bind epitopes recognized by dominant acute-phase cytotoxic-T-lymphocyte responses.J Virol2003
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