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Author Details

Humberto Mart??n
Universidad Complutense de Madrid
1991
45
21
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36861989Cytosolic pH Controls Fungal MAPK Signaling and Pathogenicity.mBio2023
36983461Special Issue "The Fungal Cell Wall Integrity Pathway".J Fungi (Basel)2023
37042757The Mitogen-Activated Protein Kinase Slt2 Promotes Asymmetric Cell Cycle Arrest and Reduces TORC1-Sch9 Signaling in Yeast Lacking the Protein Phosphatase Ptc1.Microbiol Spectr2023
36232332Neomycin Interferes with Phosphatidylinositol-4,5-Bisphosphate at the Yeast Plasma Membrane and Activates the Cell Wall Integrity Pathway.Int J Mol Sci2022
35448599Substrates of the MAPK Slt2: Shaping Yeast Cell Integrity.J Fungi (Basel)2022
36555348Manganese Stress Tolerance Depends on Yap1 and Stress-Activated MAP Kinases.Int J Mol Sci2022
33993419A walk-through MAPK structure and functionality with the 30-year-old yeast MAPK Slt2.Int Microbiol2021
33498635Differential Role of Threonine and Tyrosine Phosphorylation in the Activation and Activity of the Yeast MAPK Slt2.Int J Mol Sci2021
34436186Clotrimazole-Induced Oxidative Stress Triggers Novel Yeast Pkc1-Independent Cell Wall Integrity MAPK Pathway Circuitry.J Fungi (Basel)2021
31342212Not just the wall: the other ways to turn the yeast CWI pathway on.Int Microbiol2020
32150787Rewiring the yeast cell wall integrity (CWI) pathway through a synthetic positive feedback circuit unveils a novel role for the MAPKKK Ssk2 in CWI pathway activation.FEBS J2020
31410666Fungal Signaling: from Homeostasis to Pathogenesis.Int Microbiol2020
30959830Mitogen-Activated Protein Kinase Phosphatases (MKPs) in Fungal Signaling: Conservation, Function, and Regulation.Int J Mol Sci2019
29982335Educating in antimicrobial resistance awareness: adaptation of the Small World Initiative program to service-learning.FEMS Microbiol Lett2018
26786099An Analog-sensitive Version of the Protein Kinase Slt2 Allows Identification of Novel Targets of the Yeast Cell Wall Integrity Pathway.J Biol Chem2016
26546002Wide-Ranging Effects of the Yeast Ptc1 Protein Phosphatase Acting Through the MAPK Kinase Mkk1.Genetics2016
27216662Laser induced breakdown spectroscopy for the discrimination of Candida strains.Talanta2016
27514817Methods to Study Protein Tyrosine Phosphatases Acting on Yeast MAPKs.Methods Mol Biol2016
25736922Identification of putative negative regulators of yeast signaling through a screening for protein phosphatases acting on cell wall integrity and mating MAPK pathways.Fungal Genet Biol2015
25888283Differential genetic interactions of yeast stress response MAPK pathways.Mol Syst Biol2015
24465549A conserved non-canonical docking mechanism regulates the binding of dual specificity phosphatases to cell integrity mitogen-activated protein kinases (MAPKs) in budding and fission yeasts.PLoS One2014
23221999Phosphoproteomic analysis of protein kinase C signaling in Saccharomyces cerevisiae reveals Slt2 mitogen-activated protein kinase (MAPK)-dependent phosphorylation of eisosome core components.Mol Cell Proteomics2013
23015760The Salmonella Typhimurium effector SteC inhibits Cdc42-mediated signaling through binding to the exchange factor Cdc24 in Saccharomyces cerevisiae.Mol Biol Cell2012
21409566Phylogenetic and genetic linkage between novel atypical dual-specificity phosphatases from non-metazoan organisms.Mol Genet Genomics2011
22006927Distinct docking mechanisms mediate interactions between the Msg5 phosphatase and mating or cell integrity mitogen-activated protein kinases (MAPKs) in Saccharomyces cerevisiae.J Biol Chem2011
20641029Fine regulation of Saccharomyces cerevisiae MAPK pathways by post-translational modifications.Yeast2010
19123063Different modulation of the outputs of yeast MAPK-mediated pathways by distinct stimuli and isoforms of the dual-specificity phosphatase Msg5.Mol Genet Genomics2009
19459960A yeast-based genetic screen for identification of pathogenic Salmonella proteins.FEMS Microbiol Lett2009
17397108Dissecting the transcriptional activation function of the cell wall integrity MAP kinase.Yeast2007
17088254Signaling alkaline pH stress in the yeast Saccharomyces cerevisiae through the Wsc1 cell surface sensor and the Slt2 MAPK pathway.J Biol Chem2006
16164545Protein phosphatases in MAPK signalling: we keep learning from yeast.Mol Microbiol2005
14703512Reciprocal regulation between Slt2 MAPK and isoforms of Msg5 dual-specificity protein phosphatase modulates the yeast cell integrity pathway.J Biol Chem2004
12016210A novel connection between the yeast Cdc42 GTPase and the Slt2-mediated cell integrity pathway identified through the effect of secreted Salmonella GTPase modulators.J Biol Chem2002
11179424Peroxide sensors for the fission yeast stress-activated mitogen-activated protein kinase pathway.Mol Biol Cell2001
11370005Choline-binding domain as a novel affinity tag for purification of fusion proteins produced in Pichia pastoris.Biotechnol Bioeng2001
11459180Pim1, a MAP kinase involved in cell wall integrity in Pichia pastoris.Mol Genet Genomics2001
10625705Regulatory mechanisms for modulation of signaling through the cell integrity Slt2-mediated pathway in Saccharomyces cerevisiae.J Biol Chem2000
10974100Cell wall perturbation in yeast results in dual phosphorylation of the Slt2/Mpk1 MAP kinase and in an Slt2-mediated increase in FKS2-lacZ expression, glucanase resistance and thermotolerance.Microbiology (Reading)2000
10428959Sin1: an evolutionarily conserved component of the eukaryotic SAPK pathway.EMBO J1999
9718372Evidence for a novel MAPKKK-independent pathway controlling the stress activated Sty1/Spc1 MAP kinase in fission yeast.J Cell Sci1998
9044278Characterization of SKM1, a Saccharomyces cerevisiae gene encoding a novel Ste20/PAK-like protein kinase.Mol Microbiol1997
8662190Molecular and functional characterization of a mutant allele of the mitogen-activated protein-kinase gene SLT2(MPK1) rescued from yeast autolytic mutants.Curr Genet1996
8596433Characterization of domains in the yeast MAP kinase Slt2 (Mpk1) required for functional activity and in vivo interaction with protein kinases Mkk1 and Mkk2.Mol Microbiol1995
8232202Activity of the yeast MAP kinase homologue Slt2 is critically required for cell integrity at 37 degrees C.Mol Gen Genet1993
1779770A protein kinase gene complements the lytic phenotype of Saccharomyces cerevisiae lyt2 mutants.Mol Microbiol1991
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Collaborators

Mar??a Molina
UCM & Instituto Ramon y Cajal de Investigaciones Sanitarias (IRYCIS)
Co-authored papers 38
Pablo Fernandez-Pi??ar
Co-authored papers 4
Wendell A Lim
University of California san francisco
Co-authored papers 1
Dorothea Fiedler
Leibniz Forschungsinstitut fur Molekulare Pharmakologie (FMP)
Co-authored papers 1
Ping Wei
Fudan University Shanghai Cancer Center
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Kevan M Shokat
University of California San Francisco
Co-authored papers 1
Michael Shales
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
Co-authored papers 1
Pedro Beltrao
Institute of Molecular Systems Biology, ETH Zurich
Co-authored papers 1
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