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Author Details

John Q Trojanowski
University of Pennsylvania
1974
1300
211
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38050082Polypathologic Associations with Gray Matter Atrophy in Neurodegenerative Disease.J Neurosci2024
36192174Association of CSF GAP-43 With the Rate of Cognitive Decline and Progression to Dementia in Amyloid-Positive Individuals.Neurology2023
37808727Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cell genomics.bioRxiv2023
37703352A microtubule stabilizer ameliorates protein pathogenesis and neurodegeneration in mouse models of repetitive traumatic brain injury.Sci Transl Med2023
37898614α-Synuclein aggregates amplified from patient-derived Lewy bodies recapitulate Lewy body diseases in mice.Nat Commun2023
37499037TRIM11 protects against tauopathies and is down-regulated in Alzheimer's disease.Science2023
37972565Amyloid-Beta (Aβ) Plaques Promote Seeding and Spreading of Alpha-Synuclein and Tau in a Mouse Model of Lewy Body Disorders with Aβ Pathology.Neuron2023
37814027Author Correction: Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α-synuclein.Nat Neurosci2023
37223129Antemortem network analysis of spreading pathology in autopsy-confirmed frontotemporal degeneration.Brain Commun2023
37313492Apraxia of Speech in the Spontaneous Speech of Nonfluent/Agrammatic Primary Progressive Aphasia.J Alzheimers Dis Rep2023
37169750Glucocerebrosidase activity and lipid levels are related to protein pathologies in Parkinson's disease.NPJ Parkinsons Dis2023
37002928Preclinical characterization and IND-enabling safety studies for PNT001, an antibody that recognizes cis-pT231 tau.Alzheimers Dement2023
37163045Creating the Pick's disease International Consortium: Association study of <i>MAPT</i> H2 haplotype with risk of Pick's disease.medRxiv2023
37461624Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies <i>LRRC4C, LHX5-AS1</i> and nominates ancestry-specific loci <i>PTPRK</i> , <i>GRB14</i> , and <i>KIAA0825</i> as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium.medRxiv2023
36518085Plasma phosphorylated tau181 predicts cognitive and functional decline.Ann Clin Transl Neurol2023
36508888Event-based modeling of T1-weighted MRI is related to pathology in frontotemporal lobar degeneration due to tau and TDP.Neuroimage Clin2023
36464907Associations of phosphorylated tau pathology with whole-hemisphere ex vivo morphometry in 7 tesla MRI.Alzheimers Dement2023
36456471Abundant copathologies of polyglucosan bodies, frontotemporal lobar degeneration with TDP-43 inclusions and ageing-related tau astrogliopathy in a family with a GBE1 mutation.Neuropathol Appl Neurobiol2023
36864661Pathological combinations in neurodegenerative disease are heterogeneous and disease-associated.Brain2023
36824782Distinct biological activity of Lewy body α-Synuclein strain in mice.Res Sq2023
36930297Correction to: Isoform-specific patterns of tau burden and neuronal degeneration in MAPT-associated frontotemporal lobar degeneration.Acta Neuropathol2023
36209495Increasing participant diversity in AD research: Plans for digital screening, blood testing, and a community-engaged approach in the Alzheimer's Disease Neuroimaging Initiative 4.Alzheimers Dement2023
36239248Cerebrospinal fluid biomarker panel of synaptic dysfunction in Alzheimer's disease and other neurodegenerative disorders.Alzheimers Dement2023
34581485Using the Alzheimer's Disease Neuroimaging Initiative to improve early detection, diagnosis, and treatment of Alzheimer's disease.Alzheimers Dement2022
35768339Traumatic brain injury and post-traumatic stress disorder are not associated with Alzheimer's disease pathology measured with biomarkers.Alzheimers Dement2022
35580594Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology.Brain2022
35700626Non-tremor motor dysfunction in Lewy body dementias is associated with AD biomarkers.Parkinsonism Relat Disord2022
35727707Investigating key factors underlying neurodegeneration linked to alpha-synuclein spread.Neuropathol Appl Neurobiol2022
35762106Genetic prediction of impulse control disorders in Parkinson's disease.Ann Clin Transl Neurol2022
35395770Multimarker synaptic protein cerebrospinal fluid panels reflect TDP-43 pathology and cognitive performance in a pathological cohort of frontotemporal lobar degeneration.Mol Neurodegener2022
35568882Slow motor neurons resist pathological TDP-43 and mediate motor recovery in the rNLS8 model of amyotrophic lateral sclerosis.Acta Neuropathol Commun2022
35593028Plasma MIA, CRP, and Albumin Predict Cognitive Decline in Parkinson's Disease.Ann Neurol2022
35592691Lateralized <i>ante mortem</i> and <i>post mortem</i> pathology in a case of Lewy body disease with corticobasal syndrome.Alzheimers Dement (N Y)2022
35655068Quantitative detection of α-Synuclein and Tau oligomers and other aggregates by digital single particle counting.NPJ Parkinsons Dis2022
37250748Cerebrovascular disease lesions are additive and tied to vascular risk factors and cognitive impairment.Free Neuropathol2022
36572909ApoJ/Clusterin concentrations are determinants of cerebrospinal fluid cholesterol efflux capacity and reduced levels are associated with Alzheimer's disease.Alzheimers Res Ther2022
36112222TREM2 risk variants are associated with atypical Alzheimer's disease.Acta Neuropathol2022
35871112Regional distribution and maturation of tau pathology among phenotypic variants of Alzheimer's disease.Acta Neuropathol2022
36041863CSF Biomarkers of Alzheimer Disease in Patients With Concomitant α-Synuclein Pathology.Neurology2022
35997131Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy.Mov Disord2022
36103266Establishing an Autopsy-Based Cerebrospinal Fluid Biomarker Signature in Alzheimer Disease Patients.Clin Chem2022
36066634Isoform-specific patterns of tau burden and neuronal degeneration in MAPT-associated frontotemporal lobar degeneration.Acta Neuropathol2022
36269086Digital Histological Study of Neocortical Grey and White Matter Tau Burden Across Tauopathies.J Neuropathol Exp Neurol2022
35985146Natural speech markers of Alzheimer's disease co-pathology in Lewy body dementias.Parkinsonism Relat Disord2022
35877814Elevated Plasma Phosphorylated Tau 181 in Amyotrophic Lateral Sclerosis.Ann Neurol2022
35258081Dopamine neurons exhibit emergent glutamatergic identity in Parkinson's disease.Brain2022
35256815Single-nuclei isoform RNA sequencing unlocks barcoded exon connectivity in frozen brain tissue.Nat Biotechnol2022
35318284Divergent Histopathological Networks of Frontotemporal Degeneration Proteinopathy Subytpes.J Neurosci2022
34952351Ex vivo MRI and histopathology detect novel iron-rich cortical inflammation in frontotemporal lobar degeneration with tau versus TDP-43 pathology.Neuroimage Clin2022
35287730TMEM106B deficiency impairs cerebellar myelination and synaptic integrity with Purkinje cell loss.Acta Neuropathol Commun2022
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Collaborators

Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 706
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Co-authored papers 221
University of California San Francisco
Co-authored papers 102
Massachusetts General Hospital
Co-authored papers 95
Mayo Clinic Rochester
Co-authored papers 79
University of Pennsylvania
Co-authored papers 78
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 65
Mayo Clinic Rochester
Co-authored papers 62
Mayo Clinic Jacksonville
Co-authored papers 62
Alzheimer's Therapeutic Research Institute, University of Southern California
Co-authored papers 50
Washington University School of Medicine
Co-authored papers 48
Stanford University
Co-authored papers 47
Helen Wills Neuroscience Institute, University of California Berkeley
Co-authored papers 46
Indiana University School of Medicine
Co-authored papers 43
Co-authored papers 43
Washington University School of Medicine
Co-authored papers 43
Co-authored papers 42
Keio University School of Medicine
Co-authored papers 42
Mayo Clinic Florida
Co-authored papers 36
Indiana University School of Medicine
Co-authored papers 36
National Institute On Aging
Co-authored papers 36
Mayo Clinic Rochester
Co-authored papers 35
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 35
Lou Ruvo Center for Brain Health, Cleveland Clinic
Co-authored papers 33
University of Pennsylvania
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Rush University Medical Center
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Mayo Clinic Rochester
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UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 28
Weill Institute for Neurosciences, University of California san francisco
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University of Antwerp
Co-authored papers 26