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Author Details

Yaqiao Li
Harvard Medical School
2005
23
17
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37398236KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss.bioRxiv2023
37312453Rescue of hearing by adenine base editing in a humanized mouse model of Usher syndrome type 1F.Mol Ther2023
34669146Sex-Stratified Single-Cell RNA-Seq Analysis Identifies Sex-Specific and Cell Type-Specific Transcriptional Responses in Alzheimer's Disease Across Two Brain Regions.Mol Neurobiol2022
35857511Mechanical gating of the auditory transduction channel TMC1 involves the fourth and sixth transmembrane helices.Sci Adv2022
35572130Bioinformatics Analysis of Publicly Available Single-Nuclei Transcriptomics Alzheimer's Disease Datasets Reveals <i>APOE</i> Genotype-Specific Changes Across Cell Types in Two Brain Regions.Front Aging Neurosci2022
35413950Microglial NF-κB drives tau spreading and toxicity in a mouse model of tauopathy.Nat Commun2022
34851693AD-linked R47H-<i>TREM2</i> mutation induces disease-enhancing microglial states via AKT hyperactivation.Sci Transl Med2021
33869656AAV-S: A versatile capsid variant for transduction of mouse and primate inner ear.Mol Ther Methods Clin Dev2021
32792571Discovery of small molecules that normalize the transcriptome and enhance cysteine cathepsin activity in progranulin-deficient microglia.Sci Rep2020
31906970Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy.Mol Neurodegener2020
31873194Microglial microRNAs mediate sex-specific responses to tau pathology.Nat Neurosci2020
33054973A MAC2-positive progenitor-like microglial population is resistant to CSF1R inhibition in adult mouse brain.Elife2020
30735499Proximal recolonization by self-renewing microglia re-establishes microglial homeostasis in the adult mouse brain.PLoS Biol2019
29540553SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy.J Neurosci2018
30232263Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy.Proc Natl Acad Sci U S A2018
28068565Retinal thinning is uniquely associated with medial temporal lobe atrophy in neurologically normal older adults.Neurobiol Aging2017
28082074Rescue of Hearing by Gene Delivery to Inner-Ear Hair Cells Using Exosome-Associated AAV.Mol Ther2017
27041503Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.Neuron2016
26390242Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits.Nat Med2015
24968265The REST gene signature predicts drug sensitivity in neuroblastoma cell lines and is significantly associated with neuroblastoma tumor stage.Int J Mol Sci2014
25261995Progranulin protects against amyloid β deposition and toxicity in Alzheimer's disease mouse models.Nat Med2014
23958747A novel, highly sensitive method for assessing gap junctional coupling.J Neurosci Methods2013
16408008Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.Nat Chem Biol2005
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Collaborators

Gladstone Institutes
Co-authored papers 10
Helen and Robert Appel Alzheimer's Disease Research Institute
Co-authored papers 10
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Co-authored papers 6
Institute for Neurodegenerative Diseases, University of California San Francisco
Co-authored papers 4
Buck Institute for Research on Aging
Co-authored papers 4
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Co-authored papers 4
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Co-authored papers 4
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Co-authored papers 4
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Co-authored papers 4
Buck Institute for Research on Aging
Co-authored papers 3
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 3
Dokkyo Medical University
Co-authored papers 3
Buck Institute for Research on Aging
Co-authored papers 2
Feil Family Brain and Mind Research Institute
Co-authored papers 2
Jiangsu Simcere Pharmaceutical Co. Ltd.
Co-authored papers 2
National Institute of Neurological, National Institutes of Health (NIH)
Co-authored papers 2
Helen and Robert Appel Alzheimer's Disease Research Institute
Co-authored papers 2
National Institute On Aging
Co-authored papers 2
UCSF Weill Institute for Neurosciences, University of California san francisco
Co-authored papers 2
Albert Einstein College of Medicine
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Gladstone Institutes
Co-authored papers 2
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Gladstone Institute for Neurological Disease San Francisco
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Co-authored papers 1