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Author Details

Robert M Stephens
Frederick National Laboratory for Cancer Research, Inc.
1980
150
70
PMIDPaper TitleJournal TitlePublished Year
32393580<i>RAS</i> internal tandem duplication disrupts GTPase-activating protein (GAP) binding to activate oncogenic signaling.J Biol Chem2020
32393580<i>RAS</i> internal tandem duplication disrupts GTPase-activating protein (GAP) binding to activate oncogenic signaling.J Biol Chem2020
32581224ssGSEA score-based Ras dependency indexes derived from gene expression data reveal potential Ras addiction mechanisms with possible clinical implications.Sci Rep2020
32581224ssGSEA score-based Ras dependency indexes derived from gene expression data reveal potential Ras addiction mechanisms with possible clinical implications.Sci Rep2020
30678108Genome Assembly and Annotation of the Trichoplusia ni Tni-FNL Insect Cell Line Enabled by Long-Read Technologies.Genes (Basel)2019
31611389KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis.Proc Natl Acad Sci U S A2019
30678108Genome Assembly and Annotation of the Trichoplusia ni Tni-FNL Insect Cell Line Enabled by Long-Read Technologies.Genes (Basel)2019
31611389KRAS G13D sensitivity to neurofibromin-mediated GTP hydrolysis.Proc Natl Acad Sci U S A2019
29444439Differential Effector Engagement by Oncogenic KRAS.Cell Rep2018
30012562<i>IFNL4</i>-οG Allele Is Associated with an Interferon Signature in Tumors and Survival of African-American Men with Prostate Cancer.Clin Cancer Res2018
30517129GradientScanSurv-An exhaustive association test method for gene expression data with censored survival outcome.PLoS One2018
29444439Differential Effector Engagement by Oncogenic KRAS.Cell Rep2018
30012562<i>IFNL4</i>-οG Allele Is Associated with an Interferon Signature in Tumors and Survival of African-American Men with Prostate Cancer.Clin Cancer Res2018
30517129GradientScanSurv-An exhaustive association test method for gene expression data with censored survival outcome.PLoS One2018
28634423Tumor RAS Gene Expression Levels Are Influenced by the Mutational Status of RAS Genes and Both Upstream and Downstream RAS Pathway Genes.Cancer Inform2017
28634423Tumor RAS Gene Expression Levels Are Influenced by the Mutational Status of RAS Genes and Both Upstream and Downstream RAS Pathway Genes.Cancer Inform2017
26996949GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy.Am J Hum Genet2016
27051465Distinguishing highly similar gene isoforms with a clustering-based bioinformatics analysis of PacBio single-molecule long reads.BioData Min2016
26996949GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy.Am J Hum Genet2016
26949565Towards Better Precision Medicine: PacBio Single-Molecule Long Reads Resolve the Interpretation of HIV Drug Resistant Mutation Profiles at Explicit Quasispecies (Haplotype) Level.J Data Mining Genomics Proteomics2016
26719530An Immune-Inflammation Gene Expression Signature in Prostate Tumors of Smokers.Cancer Res2016
26899007Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts.Nat Commun2016
27894102Comparative proteomics of a model MCF10A-KRasG12V cell line reveals a distinct molecular signature of the KRasG12V cell surface.Oncotarget2016
27894102Comparative proteomics of a model MCF10A-KRasG12V cell line reveals a distinct molecular signature of the KRasG12V cell surface.Oncotarget2016
26719530An Immune-Inflammation Gene Expression Signature in Prostate Tumors of Smokers.Cancer Res2016
26899007Genome analysis of three Pneumocystis species reveals adaptation mechanisms to life exclusively in mammalian hosts.Nat Commun2016
26949565Towards Better Precision Medicine: PacBio Single-Molecule Long Reads Resolve the Interpretation of HIV Drug Resistant Mutation Profiles at Explicit Quasispecies (Haplotype) Level.J Data Mining Genomics Proteomics2016
27051465Distinguishing highly similar gene isoforms with a clustering-based bioinformatics analysis of PacBio single-molecule long reads.BioData Min2016
25738367MicroRNA-10b inhibition reduces E2F1-mediated transcription and miR-15/16 activity in glioblastoma.Oncotarget2015
25738367MicroRNA-10b inhibition reduces E2F1-mediated transcription and miR-15/16 activity in glioblastoma.Oncotarget2015
25903473The Cancer Genome Atlas Analysis Predicts MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma.Mol Ther2015
26001532The somatic autosomal mutation matrix in cancer genomes.Hum Genet2015
26071096Erratum to: The somatic autosomal mutation matrix in cancer genomes.Hum Genet2015
26071096Erratum to: The somatic autosomal mutation matrix in cancer genomes.Hum Genet2015
25903473The Cancer Genome Atlas Analysis Predicts MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma.Mol Ther2015
26001532The somatic autosomal mutation matrix in cancer genomes.Hum Genet2015
24215028AVIA: an interactive web-server for annotation, visualization and impact analysis of genomic variations.Bioinformatics2014
24316975MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.J Clin Invest2014
24215028AVIA: an interactive web-server for annotation, visualization and impact analysis of genomic variations.Bioinformatics2014
24748377Pathway-specific engineered mouse allograft models functionally recapitulate human serous epithelial ovarian cancer.PLoS One2014
24831545Performance comparison of SNP detection tools with illumina exome sequencing data--an assessment using both family pedigree information and sample-matched SNP array data.Nucleic Acids Res2014
24559646miR-126 contributes to Parkinson's disease by dysregulating the insulin-like growth factor/phosphoinositide 3-kinase signaling.Neurobiol Aging2014
24748377Pathway-specific engineered mouse allograft models functionally recapitulate human serous epithelial ovarian cancer.PLoS One2014
24831545Performance comparison of SNP detection tools with illumina exome sequencing data--an assessment using both family pedigree information and sample-matched SNP array data.Nucleic Acids Res2014
24559646miR-126 contributes to Parkinson's disease by dysregulating the insulin-like growth factor/phosphoinositide 3-kinase signaling.Neurobiol Aging2014
24316975MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.J Clin Invest2014
22370643MiR-1 and miR-200 inhibit EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms.Oncogene2013
22890324Silencing of miR-148a in cancer-associated fibroblasts results in WNT10B-mediated stimulation of tumor cell motility.Oncogene2013
22370643MiR-1 and miR-200 inhibit EMT via Slug-dependent and tumorigenesis via Slug-independent mechanisms.Oncogene2013
22986525MicroRNA-106b-25 cluster expression is associated with early disease recurrence and targets caspase-7 and focal adhesion in human prostate cancer.Oncogene2013
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Collaborators

Co-authored papers 9
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Co-authored papers 7
The University of Texas MD Anderson Cancer Center
Co-authored papers 5
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Co-authored papers 5
National Cancer Institute, National Institutes of Health
Co-authored papers 4
Institute of Medical Genetics, Cardiff University
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Women's Health Integrated Research Center, Inova Health System
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Co-authored papers 3
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 3
Inc., Frederick National Laboratory for Cancer Research
Co-authored papers 3
National Center for Biotechnology Information, National Institutes of Health
Co-authored papers 3
Institute for Quantitative Health Science and Engineering, Michigan State University
Co-authored papers 3
Center for Cancer Research, National Cancer Institute-Frederick
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Massachusetts General Hospital
Co-authored papers 2
National Human Genome Research Institute, National Institutes of Health
Co-authored papers 2
Leidos Biomedical Research Inc.
Co-authored papers 2
Children's Hospital at Montefiore.
Co-authored papers 2
Johns Hopkins School of Medicine, National Cancer Institute, Princeton University, University of Colorado Anschutz Medical Campus, University of Pittsburgh, University of Washington
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National Cancer Institute
Co-authored papers 2
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National Cancer Institute, National Institutes of Health
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Massachusetts General Hospital
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National Cancer Institute
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