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Author Details
Full Name
Tamar Uziel
Affiliation
AbbVie Inc.
ORCID
Career Start Year
1995
Papers
27
H Index
24
Expertise
CM4AI Collaborator
Antoine Forget (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36720090
Activity of eftozanermin alfa plus venetoclax in preclinical models and patients with acute myeloid leukemia.
Blood
2023
32887697
Venetoclax Increases Intratumoral Effector T Cells and Antitumor Efficacy in Combination with Immune Checkpoint Blockade.
Cancer Discov
2021
34253595
Selective Inhibition of the Second Bromodomain of BET Family Proteins Results in Robust Antitumor Activity in Preclinical Models of Acute Myeloid Leukemia.
Mol Cancer Ther
2021
31969702
Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer.
Nature
2020
29764866
LRRC15 Is a Novel Mesenchymal Protein and Stromal Target for Antibody-Drug Conjugates.
Cancer Res
2018
30266801
Targeting Lineage-specific MITF Pathway in Human Melanoma Cell Lines by A-485, the Selective Small-molecule Inhibitor of p300/CBP.
Mol Cancer Ther
2018
29769713
Author Correction: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.
Nature
2018
27707886
Exploitation of Castration-Resistant Prostate Cancer Transcription Factor Dependencies by the Novel BET Inhibitor ABBV-075.
Mol Cancer Res
2017
28416490
Preclinical Characterization of BET Family Bromodomain Inhibitor ABBV-075 Suggests Combination Therapeutic Strategies.
Cancer Res
2017
28468776
Vulnerability of Small-Cell Lung Cancer to Apoptosis Induced by the Combination of BET Bromodomain Proteins and BCL2 Inhibitors.
Mol Cancer Ther
2017
28953875
Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.
Nature
2017
28787674
The Volume of Three-Dimensional Cultures of Cancer Cells InVitro Influences Transcriptional Profile Differences and Similarities with Monolayer Cultures and Xenografted Tumors.
Neoplasia
2017
27903752
HEXIM1 as a Robust Pharmacodynamic Marker for Monitoring Target Engagement of BET Family Bromodomain Inhibitors in Tumors and Surrogate Tissues.
Mol Cancer Ther
2017
22340591
A mouse model of the most aggressive subgroup of human medulloblastoma.
Cancer Cell
2012
21132008
Mcl-1 is critical for survival in a subgroup of non-small-cell lung cancer cell lines.
Oncogene
2011
19196975
The miR-17~92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma.
Proc Natl Acad Sci U S A
2009
17363588
Genetic alterations in mouse medulloblastomas and generation of tumors de novo from primary cerebellar granule neuron precursors.
Cancer Res
2007
16479172
The CDK inhibitor p18Ink4c is a tumor suppressor in medulloblastoma.
Cell Cycle
2006
16260494
The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation.
Genes Dev
2005
14532133
Requirement of the MRN complex for ATM activation by DNA damage.
EMBO J
2003
11313957
Ataxia-telangiectasia: chronic activation of damage-responsive functions is reduced by alpha-lipoic acid.
Oncogene
2001
9199932
Ataxia-telangiectasia locus: sequence analysis of 184 kb of human genomic DNA containing the entire ATM gene.
Genome Res
1997
9108147
Ataxia-telangiectasia: structural diversity of untranslated sequences suggests complex post-transcriptional regulation of ATM gene expression.
Nucleic Acids Res
1997
8660968
A human gene (DDX10) encoding a putative DEAD-box RNA helicase at 11q22-q23.
Genomics
1996
8845835
Predominance of null mutations in ataxia-telangiectasia.
Hum Mol Genet
1996
8660985
Genomic Organization of the ATM gene.
Genomics
1996
7792600
A single ataxia telangiectasia gene with a product similar to PI-3 kinase.
Science
1995
1 - 27 of 27
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Institute of Pathology, Kings County Hospital Center
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