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Author Details

Robert Bruccoleri
1983
53
28
PMIDPaper TitleJournal TitlePublished Year
36745695Valhidepsin Lipopeptides from : Structures, Biosynthesis, and Coregulation with FR900359 Production.2023
35138454Teleocidin-producing genotype of Streptomyces clavuligerus ATCC 27064.Applied Microbiology and Biotechnology2022
31740414Identification and application of threonine aldolase for synthesis of valuable α-amino, β-hydroxy-building blocks.Biochimica et Biophysica Acta - Proteins and Proteomics2020
28457472Duplicated Enhancer Region Increases Expression of CTSB and Segregates with Keratolytic Winter Erythema in South African and Norwegian Families.Am J Hum Genet2017
25948579antiSMASH 3.0-a comprehensive resource for the genome mining of biosynthetic gene clusters.Nucleic Acids Res2015
25616894Decatransin, a new natural product inhibiting protein translocation at the Sec61/SecYEG translocon.J Cell Sci2015
21865301SDRS--an algorithm for analyzing large-scale dose-response data.2011
21918636FDR-FET: an optimizing gene set enrichment analysis method.Advances and Applications in Bioinformatics and Chemistry2011
19763178Transcriptional profiling of the dose response: a more powerful approach for characterizing drug activities.PLoS Computational Biology2009
16607011Conserved fungal genes as potential targets for broad-spectrum antifungal drug discovery.Eukaryotic Cell2006
11084909Ab initio loop modeling and its application to homology modeling.Methods in Molecular Biology2000
9742253Concordance analysis of microbial genomes.Nucleic Acids Research1998
9697194Empirical free energy calculations of phage 434 repressor- and cro-DNA complexes support the 'indirect readout' hypothesis of specificity.1998
9144767Homology modeling using simulated annealing of restrained molecular dynamics and conformational search calculations with CONGEN: application in predicting the three-dimensional structure of murine homeodomain Msx-1.Protein Sci1997
9159479Empirical free energy calculations: a blind test and further improvements to the method.Journal of Molecular Biology1997
8785269Factors influencing accuracy of computer-built models: a study based on leucine zipper GCN4 structure.Biophys J1996
8845748Simulated annealing with restrained molecular dynamics using CONGEN: energy refinement of the NMR solution structures of epidermal and type-alpha transforming growth factors.Protein Sci1996
8845749Simulated annealing with restrained molecular dynamics using a flexible restraint potential: theory and evaluation with simulated NMR constraints.Protein Sci1996
7787424High-resolution solution structure of siamycin II: novel amphipathic character of a 21-residue peptide that inhibits HIV fusion.Journal of Biomolecular NMR1995
7648016J-coupling restraint potentials for nonstereospecifically assigned methylene protons and ensemble-average calculations.Journal of Magnetic Resonance - Series B1995
8061604Contribution of a single heavy chain residue to specificity of an anti-digoxin monoclonal antibody.Protein Science1994
7691815Heavy chain position 50 is a determinant of affinity and specificity for the anti-digoxin antibody 26-10.Journal of Biological Chemistry1993
8443598Modulation of antibody affinity by a non-contact residue.Protein Science1993
8455637Characterization of an anti-digoxin antibody binding site by site-directed in vitro mutagenesis.Molecular Immunology1993
8226814Effect of heavy chain signal peptide mutations and NH2-terminal chain length on binding of anti-digoxin antibodies.Journal of Biological Chemistry1993
1438184Application of a directed conformational search for generating 3-D coordinates for protein structures from alpha-carbon coordinates.Proteins: Structure, Function and Bioinformatics1992
1303765Modeling the antigen combining site of an anti-dinitrophenyl antibody, ANO2.Protein Sci1992
1544503Solution conformation of a cyclic pentapeptide endothelin antagonist. Comparison of structures obtained from constrained dynamics and conformational search.FEBS Lett1992
1898959The specificity properties that distinguish members of a set of homologous anti-digoxin antibodies are controlled by H chain mutations.Journal of Immunology1991
1761369Stabilities of leucine zipper dimers estimated by an empirical free energy method.Int J Pept Protein Res1991
1999439Altered hapten recognition by two anti-digoxin hybridoma variants due to variable region point mutations.Journal of Biological Chemistry1991
2330371Computer analysis of mutations that affect antibody specificity.Proteins: Structure, Function and Bioinformatics1990
2168983Structure-function studies of the herpes simplex virus type 1 DNA polymerase.Journal of Virology1990
2120338A V kappa-J kappa junctional change in an antidigoxin recombinant antibody destroys digoxin-binding activity.Journal of Immunology1990
2207289Conformational sampling using high-temperature molecular dynamics.Biopolymers1990
2472656On the molecular nature of "restrictive" antigenic elements present on major histocompatibility complex (MHC) proteins.Research in Immunology1989
2475171On the attribution of binding energy in antigen-antibody complexes McPC 603, D1.3, and HyHEL-5.Biochemistry1989
2454712An improved algorithm for nucleic acid secondary structure display.1988
3186690Criteria that discriminate between native proteins and incorrectly folded models.Proteins: Structure, Function and Bioinformatics1988
3045807Protein engineering of antibody binding sites: recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli.Proceedings of the National Academy of Sciences of the United States of America1988
3419534Structure of antibody hypervariable loops reproduced by a conformational search algorithm.Nature1988
2446393Antigenicity of myohemerythrin.Science1987
25291494Protein antigenicity: a static surface property.1987
3801593Prediction of the folding of short polypeptide segments by uniform conformational sampling.Biopolymers1987
3542567Correlation among sites of limited proteolysis, enzyme accessibility and segmental mobility.FEBS Letters1987
2417241Antigenic determinants in proteins coincide with surface regions accessible to large probes (antibody domains).Proceedings of the National Academy of Sciences of the United States of America1986
29160574Spatially constrained minimization of macromolecules.J Comput Chem1986
19431658Two-stranded alpha-helical coiled-coils of fibrous proteins: theoretical analysis of supercoil formation.Biophysical Journal1986
3768485The hinge-bending mode of a lysozyme-inhibitor complex.Biopolymers1986
4093982Domain association in immunoglobulin molecules. The packing of variable domains.J Mol Biol1985
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