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Author Details
Full Name
Valina L Dawson
Affiliation
Institute for Cell Engineering, Johns Hopkins University School of Medicine
ORCID
Career Start Year
1988
Papers
389
H Index
129
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36710687
DNA Methylation Signature of Aging: Potential Impact on the Pathogenesis of Parkinson's Disease.
J Parkinsons Dis
2023
38019930
Enhanced mTORC1 signaling and protein synthesis in pathologic α-synuclein cellular and animal models of Parkinson's disease.
Sci Transl Med
2023
37647389
Farnesol prevents aging-related muscle weakness in mice through enhanced farnesylation of Parkin-interacting substrate.
Sci Transl Med
2023
38071218
Inhibition of host PARP1 contributes to the anti-inflammatory and antitubercular activity of pyrazinamide.
Nat Commun
2023
37870275
PARIS undergoes liquid-liquid phase separation and poly(ADP-ribose)-mediated solidification.
EMBO Rep
2023
36652533
The c-Abl inhibitor IkT-148009 suppresses neurodegeneration in mouse models of heritable and sporadic Parkinson's disease.
Sci Transl Med
2023
36710687
DNA Methylation Signature of Aging: Potential Impact on the Pathogenesis of Parkinson's Disease.
J Parkinsons Dis
2023
37425943
Defects in Mitochondrial Biogenesis Drive Mitochondrial Alterations in PINK1-deficient Human Dopamine Neurons.
bioRxiv
2023
37296356
The Effects of NLY01, a Novel Glucagon-Like Peptide-1 Receptor Agonist, on Cuprizone-Induced Demyelination and Remyelination: Challenges and Future Perspectives.
Neurotherapeutics
2023
37293032
Pathological Tau transmission initiated by binding lymphocyte-activation gene 3.
bioRxiv
2023
37100955
Apoptotic cell death in disease-Current understanding of the NCCD 2023.
Cell Death Differ
2023
36724785
Bi-allelic TTI1 variants cause an autosomal-recessive neurodevelopmental disorder with microcephaly.
Am J Hum Genet
2023
38019930
Enhanced mTORC1 signaling and protein synthesis in pathologic α-synuclein cellular and animal models of Parkinson's disease.
Sci Transl Med
2023
38071218
Inhibition of host PARP1 contributes to the anti-inflammatory and antitubercular activity of pyrazinamide.
Nat Commun
2023
37647389
Farnesol prevents aging-related muscle weakness in mice through enhanced farnesylation of Parkin-interacting substrate.
Sci Transl Med
2023
37870275
PARIS undergoes liquid-liquid phase separation and poly(ADP-ribose)-mediated solidification.
EMBO Rep
2023
37425943
Defects in Mitochondrial Biogenesis Drive Mitochondrial Alterations in PINK1-deficient Human Dopamine Neurons.
bioRxiv
2023
37100955
Apoptotic cell death in disease-Current understanding of the NCCD 2023.
Cell Death Differ
2023
37296356
The Effects of NLY01, a Novel Glucagon-Like Peptide-1 Receptor Agonist, on Cuprizone-Induced Demyelination and Remyelination: Challenges and Future Perspectives.
Neurotherapeutics
2023
37293032
Pathological Tau transmission initiated by binding lymphocyte-activation gene 3.
bioRxiv
2023
36724785
Bi-allelic TTI1 variants cause an autosomal-recessive neurodevelopmental disorder with microcephaly.
Am J Hum Genet
2023
36652533
The c-Abl inhibitor IkT-148009 suppresses neurodegeneration in mouse models of heritable and sporadic Parkinson's disease.
Sci Transl Med
2023
34323016
ADP-ribosyltransferases, an update on function and nomenclature.
FEBS J
2022
35394877
STING mediates neurodegeneration and neuroinflammation in nigrostriatal α-synucleinopathy.
Proc Natl Acad Sci U S A
2022
36044549
Amelioration of pathologic α-synuclein-induced Parkinson's disease by irisin.
Proc Natl Acad Sci U S A
2022
35654037
Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease.
Neuron
2022
36103513
Poly(ADP-ribose) promotes toxicity of <i>C9ORF72</i> arginine-rich dipeptide repeat proteins.
Sci Transl Med
2022
36280265
The Absence of Parkin Does Not Promote Dopamine or Mitochondrial Dysfunction in PolgA[D257A/D257A] Mitochondrial Mutator Mice.
J Neurosci
2022
35363524
Deubiquitinase CYLD acts as a negative regulator of dopamine neuron survival in Parkinson's disease.
Sci Adv
2022
35412917
A high-affinity cocaine binding site associated with the brain acid soluble protein 1.
Proc Natl Acad Sci U S A
2022
36125899
Pharmacologic inhibition of MIF nuclease: A new treatment paradigm to treat cell death.
Clin Transl Med
2022
35545089
PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson's disease.
Cell
2022
36378485
Cell Biology of Parkin: Clues to the Development of New Therapeutics for Parkinson's Disease.
CNS Drugs
2022
35977929
AAAâ¿¿+â¿¿ATPase Thorase inhibits mTOR signaling through the disassembly of the mTOR complex 1.
Nat Commun
2022
34247782
CYFIP1 Dosages Exhibit Divergent Behavioral Impact via Diametric Regulation of NMDA Receptor Complex Translation in Mouse Models of Psychiatric Disorders.
Biol Psychiatry
2022
34323016
ADP-ribosyltransferases, an update on function and nomenclature.
FEBS J
2022
34744054
Waiting for PARIS-A Biological Target in Search of a Drug.
J Parkinsons Dis
2022
35172141
Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein.
Cell Rep
2022
35654037
Neuronal NLRP3 is a parkin substrate that drives neurodegeneration in Parkinson's disease.
Neuron
2022
35545089
PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson's disease.
Cell
2022
35394877
STING mediates neurodegeneration and neuroinflammation in nigrostriatal α-synucleinopathy.
Proc Natl Acad Sci U S A
2022
35363524
Deubiquitinase CYLD acts as a negative regulator of dopamine neuron survival in Parkinson's disease.
Sci Adv
2022
35412917
A high-affinity cocaine binding site associated with the brain acid soluble protein 1.
Proc Natl Acad Sci U S A
2022
36280265
The Absence of Parkin Does Not Promote Dopamine or Mitochondrial Dysfunction in PolgA[D257A/D257A] Mitochondrial Mutator Mice.
J Neurosci
2022
36044549
Amelioration of pathologic α-synuclein-induced Parkinson's disease by irisin.
Proc Natl Acad Sci U S A
2022
36103513
Poly(ADP-ribose) promotes toxicity of <i>C9ORF72</i> arginine-rich dipeptide repeat proteins.
Sci Transl Med
2022
36125899
Pharmacologic inhibition of MIF nuclease: A new treatment paradigm to treat cell death.
Clin Transl Med
2022
36378485
Cell Biology of Parkin: Clues to the Development of New Therapeutics for Parkinson's Disease.
CNS Drugs
2022
35977929
AAAâ¿¿+â¿¿ATPase Thorase inhibits mTOR signaling through the disassembly of the mTOR complex 1.
Nat Commun
2022
35172141
Interleukin-6 triggers toxic neuronal iron sequestration in response to pathological α-synuclein.
Cell Rep
2022
1 - 50 of 778
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Oncode Institute
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