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Author Details

Brian James
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
1995
25
15
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36747824The lung employs an intrinsic surfactant-mediated inflammatory response for viral defense.bioRxiv2023
34140316IL-6 contributes to metastatic switch via the differentiation of monocytic-dendritic progenitors into prometastatic immune cells.J Immunother Cancer2021
33632871Identification and Characterization of IMD-0354 as a Glutamine Carrier Protein Inhibitor in Melanoma.Mol Cancer Ther2021
32510550Glutamine depletion regulates Slug to promote EMT and metastasis in pancreatic cancer.J Exp Med2020
32571981SPANX Control of Lamin A/C Modulates Nuclear Architecture and Promotes Melanoma Growth.Mol Cancer Res2020
32839770SARS-CoV-2 ORF9c Is a Membrane-Associated Protein that Suppresses Antiviral Responses in Cells.bioRxiv2020
32532796A myelin basic protein fragment induces sexually dimorphic transcriptome signatures of neuropathic pain in mice.J Biol Chem2020
31585939Absence of HIF1A Leads to Glycogen Accumulation and an Inflammatory Response That Enables Pancreatic Tumor Growth.Cancer Res2019
30232010Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis.Cell Rep2018
30003124E47 Governs the MYC-CDKN1B/p27<sup>KIP1</sup>-RB Network to Growth Arrest PDA Cells Independent of CDKN2A/p16<sup>INK4A</sup> and Wild-Type p53.Cell Mol Gastroenterol Hepatol2018
29212953The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion.JCI Insight2017
27210757A Transcriptionally Inactive ATF2 Variant Drives Melanomagenesis.Cell Rep2016
27261507Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1α Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target.Cancer Res2016
26460303Phase II Pilot Study of Vemurafenib in Patients With Metastatic BRAF-Mutated Colorectal Cancer.J Clin Oncol2015
26603897SBI-0640756 Attenuates the Growth of Clinically Unresponsive Melanomas by Disrupting the eIF4F Translation Initiation Complex.Cancer Res2015
24669013Expression profiling stratifies mesothelioma tumors and signifies deregulation of spindle checkpoint pathway and microtubule network with therapeutic implications.Ann Oncol2014
23633488Hypoxia triggers hedgehog-mediated tumor-stromal interactions in pancreatic cancer.Cancer Res2013
23636329EGFR modulates microRNA maturation in response to hypoxia through phosphorylation of AGO2.Nature2013
23659968ETS2 mediated tumor suppressive function and MET oncogene inhibition in human non-small cell lung cancer.Clin Cancer Res2013
20126523Functional characterization of transcription factor motifs using cross-species comparison across large evolutionary distances.PLoS Comput Biol2010
19135146Superoxide dismutase is regulated by LAMMER kinase in Drosophila and human cells.Free Radic Biol Med2009
18376310Identification of thioredoxin-interacting protein 1 as a hypoxia-inducible factor 1alpha-induced gene in pancreatic cancer.Pancreas2008
17699602Nuclear localization of the ERK MAP kinase mediated by Drosophila alphaPS2betaPS integrin and importin-7.Mol Biol Cell2007
10556052Spire contains actin binding domains and is related to ascidian posterior end mark-5.Development1999
7590229Cappuccino, a Drosophila maternal effect gene required for polarity of the egg and embryo, is related to the vertebrate limb deformity locus.Genes Dev1995
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Collaborators

Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 8
PHusis Therapeutics Inc.
Co-authored papers 6
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Co-authored papers 4
Sungkyunkwan University
Co-authored papers 3
NCI-Designated Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 3
University Hospital Zurich
Co-authored papers 2
Co-authored papers 2
University of California San Diego
Co-authored papers 2
University Hospital Zurich
Co-authored papers 2
McGill University
Co-authored papers 2
Lilly Research Laboratories
Co-authored papers 2
Co-authored papers 2
Yale School of Medicine
Co-authored papers 2
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
Moffitt Cancer Center
Co-authored papers 2
Co-authored papers 1
Memorial Sloan-Kettering Cancer Center
Co-authored papers 1
Co-authored papers 1
University of Geneva Medical School
Co-authored papers 1
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
Center for Computational Biology & Bioinformatics (CCBB), University of California
Co-authored papers 1
Co-authored papers 1
University of Rochester
Co-authored papers 1
University of California berkeley
Co-authored papers 1
Ellen and Ronald Caplan Cancer Center, The Wistar Institute
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Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
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Sanford Burnham Prebys Medical Discovery Institute
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Fels Cancer Institute for Personalized Medicine, Temple University School of Medicine
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Konkuk University
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