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Author Details

Seung K Kim
Stanford University School of Medicine
1990
110
53
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36730473A genetic strategy to measure insulin signaling regulation and physiology in Drosophila.PLoS Genet2023
37279923Generation of LexA enhancer-trap lines in Drosophila by an international scholastic network.G3 (Bethesda)2023
37231096Integrating genetics with single-cell multiomic measurements across disease states identifies mechanisms of beta cell dysfunction in type 2 diabetes.Nat Genet2023
36848578Multifaceted role for p53 in pancreatic cancer suppression.Proc Natl Acad Sci U S A2023
36543916A genome-wide CRISPR screen identifies CALCOCO2 as a regulator of beta cell function influencing type 2 diabetes risk.Nat Genet2023
36711922Integration of single-cell multiomic measurements across disease states with genetics identifies mechanisms of beta cell dysfunction in type 2 diabetes.bioRxiv2023
35081145Cryopreservation and post-thaw characterization of dissociated human islet cells.PLoS One2022
35733248Single-cell transcriptome and accessible chromatin dynamics during endocrine pancreas development.Proc Natl Acad Sci U S A2022
35641781Islet cell replacement and transplantation immunology in a mouse strain with inducible diabetes.Sci Rep2022
36351397Curative islet and hematopoietic cell transplantation in diabetic mice without toxic bone marrow conditioning.Cell Rep2022
35100369Transgenic Drosophila lines for LexA-dependent gene and growth regulation.G3 (Bethesda)2022
35239393Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly.Science2022
35108513Heterogenous impairment of α cell function in type 2 diabetes is linked to cell maturation state.Cell Metab2022
33212097Single-Nucleus and In Situ RNA-Sequencing Reveal Cell Topographies in the Human Pancreas.Gastroenterology2021
34385262Discovery of ciliary G protein-coupled receptors regulating pancreatic islet insulin and glucagon secretion.Genes Dev2021
34416394What is a β cell? - Chapter I in the Human Islet Research Network (HIRN) review series.Mol Metab2021
34139200Discovering signaling mechanisms governing metabolism and metabolic diseases with Drosophila.Cell Metab2021
33947722Pancreatic Pseudoislets: An Organoid Archetype for Metabolism Research.Diabetes2021
33446570SIX2 and SIX3 coordinately regulate functional maturity and fate of human pancreatic β cells.Genes Dev2021
32350130Lactation improves pancreatic β cell mass and function through serotonin production.Sci Transl Med2020
31842084The Effect of Hyaluronidase on the Fat Graft.J Craniofac Surg2020
31806625Serotonin Regulates Adult β-Cell Mass by Stimulating Perinatal β-Cell Proliferation.Diabetes2020
32694729In vivo studies of glucagon secretion by human islets transplanted in mice.Nat Metab2020
32302527Patch-Seq Links Single-Cell Transcriptomes to Human Islet Dysfunction in Diabetes.Cell Metab2020
30378044Spheroid Culture of Human Pancreatic Ductal Cells to Reconstitute Development of Pancreatic Intraepithelial Neoplasia.Methods Mol Biol2019
31775208Considerations for patient selection: Prepectoral versus subpectoral implant-based breast reconstruction.Arch Plast Surg2019
31040111An Interscholastic Network To Generate LexA Enhancer Trap Lines in Drosophila.G3 (Bethesda)2019
30944357Modeling Spatial Correlation of Transcripts with Application to Developing Pancreas.Sci Rep2019
29414689Suppression of Insulin Production and Secretion by a Decretin Hormone.Cell Metab2018
30242153Discovering human diabetes-risk gene function with genetics and physiological assays.Nat Commun2018
30145115A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas.Cell Syst2018
29702529The Interface of Pancreatic Cancer With Diabetes, Obesity, and Inflammation: Research Gaps and Opportunities: Summary of a National Institute of Diabetes and Digestive and Kidney Diseases Workshop.Pancreas2018
28920919Age-dependent human β cell proliferation induced by glucagon-like peptide 1 and calcineurin signaling.J Clin Invest2017
28272465Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells.Nat Commun2017
28215845Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx.Cell Metab2017
28119131Dnmt1 activity is dispensable in δ-cells but is essential for α-cell homeostasis.Int J Biochem Cell Biol2017
28965763Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns.Cell2017
29046484T cells expressing chimeric antigen receptor promote immune tolerance.JCI Insight2017
29017057A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer.Cancer Cell2017
28724969Pathways to clinical CLARITY: volumetric analysis of irregular, soft, and heterogeneous tissues in development and disease.Sci Rep2017
28893946A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.Development2017
27053133Using Drosophila to discover mechanisms underlying type 2 diabetes.Dis Model Mech2016
27833043Efficient generation of pancreatic β-like cells from the mouse gallbladder.Stem Cell Res2016
27527793A Drosophila LexA Enhancer-Trap Resource for Developmental Biology and Neuroendocrine Research.G3 (Bethesda)2016
27217483Gestational Diabetes Mellitus From Inactivation of Prolactin Receptor and MafB in Islet β-Cells.Diabetes2016
27133132Age-Dependent Pancreatic Gene Regulation Reveals Mechanisms Governing Human β Cell Function.Cell Metab2016
26745668Research Resource: Genetic Labeling of Human Islet Alpha Cells.Mol Endocrinol2016
25651184Suppression of insulin production and secretion by a decretin hormone.Cell Metab2015
26494786A cellular, molecular, and pharmacological basis for appendage regeneration in mice.Genes Dev2015
26178787Pancreatic cancer modeling using retrograde viral vector delivery and in vivo CRISPR/Cas9-mediated somatic genome editing.Genes Dev2015
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Collaborators

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Co-authored papers 6
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Co-authored papers 3
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University of Science and Technology of China
Co-authored papers 3
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Co-authored papers 3
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Center for Epigenomics, University of California San Diego
Co-authored papers 2
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Co-authored papers 2
Department of Genetics and Institute for Diabetes, University of Pennsylvania
Co-authored papers 2
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Broad Institute
Co-authored papers 1
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Harvard University
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