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Author Details

Avrum Spira
Boston University School of Medicine
1997
165
52
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36229050Bronchial gene expression alterations associated with radiological bronchiectasis.Eur Respir J2023
37500728Single-molecule genome-wide mutation profiles of cell-free DNA for non-invasive detection of cancer.Nat Genet2023
37567908Integrative genetic and genomic networks identify microRNA associated with COPD and ILD.Sci Rep2023
37150829Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression.J Exp Clin Cancer Res2023
37477508Single-Cell Characterization of Pulmonary Nodules Implicates Suppression of Immunosurveillance across Early Stages of Lung Adenocarcinoma.Cancer Res2023
33972452Bronchial gene expression signature associated with rate of subsequent FEV<sub>1</sub> decline in individuals with and at risk of COPD.Thorax2022
35740559Clinical Study of Aspirin and Zileuton on Biomarkers of Tobacco-Related Carcinogenesis in Current Smokers.Cancers (Basel)2022
35830375Clinical validation and utility of Percepta GSC for the evaluation of lung cancer.PLoS One2022
36307504Smoking modulates different secretory subpopulations expressing SARS-CoV-2 entry genes in the nasal and bronchial airways.Sci Rep2022
36098652The Single-Cell Immunogenomic Landscape of B and Plasma Cells in Early-Stage Lung Adenocarcinoma.Cancer Discov2022
34675046The molecular and cellular mechanisms associated with the destruction of terminal bronchioles in COPD.Eur Respir J2022
32758562Impact of the Percepta Genomic Classifier on Clinical Management Decisions in a Multicenter Prospective Study.Chest2021
33903236Aberrant epithelial polarity cues drive the development of precancerous airway lesions.Proc Natl Acad Sci U S A2021
33862585The transition from normal lung anatomy to minimal and established fibrosis in idiopathic pulmonary fibrosis (IPF).EBioMedicine2021
33809063Single-Cell Expression Landscape of SARS-CoV-2 Receptor <i>ACE2</i> and Host Proteases in Normal and Malignant Lung Tissues from Pulmonary Adenocarcinoma Patients.Cancers (Basel)2021
34794107Pathologic and gene expression comparison of CT- screen detected and routinely detected stage I/0 lung adenocarcinoma in NCCN risk-matched cohorts.Cancer Treat Res Commun2021
34464235Integrated Biomarkers for the Management of Indeterminate Pulmonary Nodules.Am J Respir Crit Care Med2021
34580161Elevated T cell repertoire diversity is associated with progression of lung squamous cell premalignant lesions.J Immunother Cancer2021
33972311Resolving the Spatial and Cellular Architecture of Lung Adenocarcinoma by Multiregion Single-Cell Sequencing.Cancer Discov2021
32946850Distinguishing Smoking-Related Lung Disease Phenotypes Via Imaging and Molecular Features.Chest2021
32730093Augmented Lipocalin-2 Is Associated with Chronic Obstructive Pulmonary Disease and Counteracts Lung Adenocarcinoma Development.Am J Respir Crit Care Med2021
31610044Characterizing peak exposure of secondhand smoke using a real-time PM<sub>2.5</sub> monitor.Indoor Air2020
32044442Transcriptomic changes in the nasal epithelium associated with diesel engine exhaust exposure.Environ Int2020
33060632Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD.Sci Rep2020
33093160Biomarkers for Lung Cancer Screening and Detection.Cancer Epidemiol Biomarkers Prev2020
32512511Low oxygen saturation during sleep reduces CD1D and RAB20 expressions that are reversed by CPAP therapy.EBioMedicine2020
30529598Biomarkers in Lung Cancer Screening: Achievements, Promises, and Challenges.J Thorac Oncol2019
31844660Characterizing smoking-induced transcriptional heterogeneity in the human bronchial epithelium at single-cell resolution.Sci Adv2019
31233743Gene Expression Alterations in the Bronchial Epithelium of e-Cigarette Users.Chest2019
31451521Effect of Intermittent Versus Continuous Low-Dose Aspirin on Nasal Epithelium Gene Expression in Current Smokers: A Randomized, Double-Blinded Trial.Cancer Prev Res (Phila)2019
31015447Molecular subtyping reveals immune alterations associated with progression of bronchial premalignant lesions.Nat Commun2019
30896962Driver Mutations in Normal Airway Epithelium Elucidate Spatiotemporal Resolution of Lung Cancer.Am J Respir Crit Care Med2019
31061400Tobacco-Related Alterations in Airway Gene Expression are Rapidly Reversed Within Weeks Following Smoking-Cessation.Sci Rep2019
31142513The Immune Contexture Associates with the Genomic Landscape in Lung Adenomatous Premalignancy.Cancer Res2019
30846474Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in COPD.Eur Respir J2019
30845938Detection of early lung cancer among military personnel (DECAMP) consortium: study protocols.BMC Pulm Med2019
30464018Electronic cigarettes: a task force report from the European Respiratory Society.Eur Respir J2019
30664780Deciphering the genomic, epigenomic, and transcriptomic landscapes of pre-invasive lung cancer lesions.Nat Med2019
30383540An airway epithelial IL-17A response signature identifies a steroid-unresponsive COPD patient subgroup.J Clin Invest2019
29072842Impact of Chronic Obstructive Pulmonary Disease on Immune-based Treatment for Lung Cancer. Moving toward Disease Interception.Am J Respir Crit Care Med2018
30072506microRNA-mRNA regulatory networks underlying chronic mucus hypersecretion in COPD.Eur Respir J2018
29932825Impact of acute exposure to cigarette smoke on airway gene expression.Physiol Genomics2018
30425966Transcriptomic Alterations in Lung Adenocarcinoma Unveil New Mechanisms Targeted by the <i>TBX2</i> Subfamily of Tumor Suppressor Genes.Front Oncol2018
30640517Current Status and Future Opportunities in Lung Precision Medicine Research with a Focus on Biomarkers. An American Thoracic Society/National Heart, Lung, and Blood Institute Research Statement.Am J Respir Crit Care Med2018
29382653Genome-Wide Gene Expression Changes in the Normal-Appearing Airway during the Evolution of Smoking-Associated Lung Adenocarcinoma.Cancer Prev Res (Phila)2018
29463557The Airway Transcriptome as a Biomarker for Early Lung Cancer Detection.Clin Cancer Res2018
29601802Impact of an Interdisciplinary Computational Research Section in a Department of Medicine: An 8-Year Perspective.Am J Med2018
29510677Summarizing performance for genome scale measurement of miRNA: reference samples and metrics.BMC Genomics2018
29624449Defining Impaired Respiratory Health. A Paradigm Shift for Pulmonary Medicine.Am J Respir Crit Care Med2018
27856720Nondestructive cryomicro-CT imaging enables structural and molecular analysis of human lung tissue.J Appl Physiol (1985)2017
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