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Author Details

Adam S Fleisher
Banner Alzheimer's Institute, University of California
2001
120
57
PMIDPaper TitleJournal TitlePublished Year
36855201Early tau detection in flortaucipir images: validation in autopsy-confirmed data and implications for disease progression.Alzheimers Res Ther2023
35099509Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum.JAMA Neurol2022
35191506Hemispheric Asymmetry and Atypical Lobar Progression of Alzheimer-Type Tauopathy.J Neuropathol Exp Neurol2022
34585215Donanemab (LY3002813) Phase 1b Study in Alzheimer's Disease: Rapid and Sustained Reduction of Brain Amyloid Measured by Florbetapir F18 Imaging.J Prev Alzheimers Dis2021
33682705Relationships Between Cognition and Neuropathological Tau in Alzheimer's Disease Assessed by 18F Flortaucipir PET.J Alzheimers Dis2021
33614894Lanabecestat: Neuroimaging results in early symptomatic Alzheimer's disease.Alzheimers Dement (N Y)2021
32338734Positron Emission Tomography Imaging With [18F]flortaucipir and Postmortem Assessment of Alzheimer Disease Neuropathologic Changes.JAMA Neurol2020
29188296Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia.JAMA Psychiatry2018
29799984Use of Flutemetamol F 18-Labeled Positron Emission Tomography and Other Biomarkers to Assess Risk of Clinical Progression in Patients With Amnestic Mild Cognitive Impairment.JAMA Neurol2018
29955651A simulation study comparing slope model with mixed-model repeated measure to assess cognitive data in clinical trials of Alzheimer's disease.Alzheimers Dement (N Y)2018
30326851Retrospective assessment of patient characteristics and healthcare costs prior to a diagnosis of Alzheimer's disease in an administrative claims database.BMC Geriatr2018
29780867Topographic staging of tau positron emission tomography images.Alzheimers Dement (Amst)2018
29601787Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.Alzheimers Dement2018
28795133Performance of [<sup>18</sup>F]flutemetamol amyloid imaging against the neuritic plaque component of CERAD and the current (2012) NIA-AA recommendations for the neuropathologic diagnosis of Alzheimer's disease.Alzheimers Dement (Amst)2017
28365320Use of white matter reference regions for detection of change in florbetapir positron emission tomography from completed phase 3 solanezumab trials.Alzheimers Dement2017
28410658The Role of Neuroimaging in the Assessment of the Cognitively Impaired Elderly.Neurol Clin2017
27733827A Triple Network Connectivity Study of Large-Scale Brain Systems in Cognitively Normal APOE4 Carriers.Front Aging Neurosci2016
28229124Functional limitations and health care resource utilization for individuals with cognitive impairment without dementia: Findings from a United States population-based survey.Alzheimers Dement (Amst)2016
25580592Associations between biomarkers and age in the presenilin 1 E280A autosomal dominant Alzheimer disease kindred: a cross-sectional study.JAMA Neurol2015
27239516Clinical use of amyloid-positron emission tomography neuroimaging: Practical and bioethical considerations.Alzheimers Dement (Amst)2015
26156687Striatal and Pallidal Activation during Reward Modulated Movement Using a Translational Paradigm.J Int Neuropsychol Soc2015
26121081Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease: A Cross-Sectional Study.JAMA Neurol2015
25849033Florbetapir PET, FDG PET, and MRI in Down syndrome individuals with and without Alzheimer's dementia.Alzheimers Dement2015
25873426Aberrant white matter networks mediate cognitive impairment in patients with silent lacunar infarcts in basal ganglia territory.J Cereb Blood Flow Metab2015
25988462Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.JAMA2015
25988463Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis.JAMA2015
25622185Phase 3 trial of flutemetamol labeled with radioactive fluorine 18 imaging and neuritic plaque density.JAMA Neurol2015
25745091Improved power for characterizing longitudinal amyloid-β PET changes and evaluating amyloid-modifying treatments with a cerebral white matter reference region.J Nucl Med2015
23562429Subjective cognitive decline: self and informant comparisons.Alzheimers Dement2014
25070071The value of biomarker comparisons between autosomal dominant and late-onset Alzheimer disease.JAMA Neurol2014
24751827An empirically derived composite cognitive test score with improved power to track and evaluate treatments for preclinical Alzheimer's disease.Alzheimers Dement2014
24747536In vivo performance of a microfabricated catheter for intraparenchymal delivery.J Neurosci Methods2014
24816373The Alzheimer's prevention initiative composite cognitive test score: sample size estimates for the evaluation of preclinical Alzheimer's disease treatments in presenilin 1 E280A mutation carriers.J Clin Psychiatry2014
24946874Aberrant functional networks connectivity and structural atrophy in silent lacunar infarcts: relationship with cognitive impairments.J Alzheimers Dis2014
24940515Out of sight, out of mind: the case of a 62-year-old man with visual complaints and cognitive decline.Prim Care Companion CNS Disord2014
24614494Florbetapir F 18 amyloid PET and 36-month cognitive decline: a prospective multicenter study.Mol Psychiatry2014
24614201Structural and functional brain changes in the default mode network in subtypes of amnestic mild cognitive impairment.J Geriatr Psychiatry Neurol2014
24335535Neuropathologic heterogeneity does not impair florbetapir-positron emission tomography postmortem correlates.J Neuropathol Exp Neurol2014
24276092Brain differences in infants at differential genetic risk for late-onset Alzheimer disease: a cross-sectional imaging study.JAMA Neurol2014
24411134A phase1 study of stereotactic gene delivery of AAV2-NGF for Alzheimer's disease.Alzheimers Dement2014
24164929Neuropsychiatric symptoms and regional neocortical atrophy in mild cognitive impairment and Alzheimer's disease.Am J Alzheimers Dis Other Demen2014
23583233Fibrillar amyloid correlates of preclinical cognitive decline.Alzheimers Dement2014
23541188The neuropsychology of normal aging and preclinical Alzheimer's disease.Alzheimers Dement2014
22665720A sparse structure learning algorithm for Gaussian Bayesian Network identification from high-dimensional data.IEEE Trans Pattern Anal Mach Intell2013
24511437Hypersexuality in dementia: a case presentation with discussion.Prim Care Companion CNS Disord2013
24252435Clinical and multimodal biomarker correlates of ADNI neuropathological findings.Acta Neuropathol Commun2013
24171149A rapid turn of events: sudden physical and cognitive decline.Prim Care Companion CNS Disord2013
23840615Association between an Alzheimer's Disease-Related Index and APOE ε4 Gene Dose.PLoS One2013
23836404Genetic susceptibility for Alzheimer disease neuritic plaque pathology.JAMA Neurol2013
23930237As time goes by.Prim Care Companion CNS Disord2013
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Collaborators

Beijing Normal University
Co-authored papers 50
Banner Alzheimer's Institute
Co-authored papers 48
Banner Alzheimer's Institute
Co-authored papers 28
Mallinckrodt Institute of Radiology , Washington University School of Medicine
Co-authored papers 20
Banner Alzheimer's Institute
Co-authored papers 15
Evelyn F. McKnight Brain Institute, University of Arizona
Co-authored papers 15
University of California San Francisco
Co-authored papers 14
Barrow Neurological Institute
Co-authored papers 13
Helen Wills Neuroscience Institute, University of California Berkeley
Co-authored papers 12
Premier Research Institute and NOVA SE University
Co-authored papers 12
Duke University School of Medicine
Co-authored papers 10
Mayo Clinic Rochester
Co-authored papers 10
University of Southern California
Co-authored papers 9
Brigham and Women's Hospital, Massachusetts General Hospital
Co-authored papers 9
Alzheimer's Therapeutic Research Institute, University of Southern California
Co-authored papers 9
University of California davis
Co-authored papers 8
Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School
Co-authored papers 7
University of Texas Southwestern Medical Center
Co-authored papers 7
The Translational Genomics Research Institute (TGen)
Co-authored papers 7
Brain Health Imaging Institute
Co-authored papers 7
University of Pennsylvania
Co-authored papers 7
Washington University School of Medicine
Co-authored papers 6
Duke University School of Medicine
Co-authored papers 6
University of California San Diego
Co-authored papers 6
University of Michigan ann arbor
Co-authored papers 6
University of Utah
Co-authored papers 6
University of California san francisco
Co-authored papers 6
Butler Hospital, and Warren Alpert Medical School of Brown University
Co-authored papers 5
Mayo Clinic Rochester
Co-authored papers 5
Mayo Clinic
Co-authored papers 5