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Author Details

Raphael H Valdivia
Duke University
1978
102
40
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36909574The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting <i>Chlamydia</i> effectors from degradation.bioRxiv2023
37530528The <i>Chlamydia</i> effector CpoS modulates the inclusion microenvironment and restricts the interferon response by acting on Rab35.mBio2023
37526424Spontaneous episodic inflammation in the intestines of mice lacking HNF4A is driven by microbiota and associated with early life microbiota alterations.mBio2023
37416863Use of gene sequences as type for naming prokaryotes: Recommendations of the international committee on the taxonomy of chlamydiae.New Microbes New Infect2023
37247566The emerging complexity of Chlamydia trachomatis interactions with host cells as revealed by molecular genetic approaches.Curr Opin Microbiol2023
37337046A genetic system for Akkermansia muciniphila reveals a role for mucin foraging in gut colonization and host sterol biosynthesis gene expression.Nat Microbiol2023
36084633The bacterial effector GarD shields Chlamydia trachomatis inclusions from RNF213-mediated ubiquitylation and destruction.Cell Host Microbe2022
36179667Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease.Cell2022
36395759Chlamydia repurposes the actin-binding protein EPS8 to disassemble epithelial tight junctions and promote infection.Cell Host Microbe2022
33468625An endometrial organoid model of interactions between <i>Chlamydia</i> and epithelial and immune cells.J Cell Sci2021
33685970Application of a <i>C. trachomatis</i> expression system to identify <i>C. pneumoniae</i> proteins translocated into host cells.J Bacteriol2021
33624438The Pediatric Obesity Microbiome and Metabolism Study (POMMS): Methods, Baseline Data, and Early Insights.Obesity (Silver Spring)2021
35047856Human genetic diversity regulating the TLR10/TLR1/TLR6 locus confers increased cytokines in response to Chlamydia trachomatis.HGG Adv2021
34006653Genotypic and Phenotypic Diversity among Human Isolates of Akkermansia muciniphila.mBio2021
33106516Modeling of variables in cellular infection reveals CXCL10 levels are regulated by human genetic variation and the Chlamydia-encoded CPAF protease.Sci Rep2020
32044689Bacterial genetics and molecular pathogenesis in the age of high throughput DNA sequencing.Curr Opin Microbiol2020
30375511Chlamydia trachomatis fails to protect its growth niche against pro-apoptotic insults.Cell Death Differ2019
31697687Insertional mutagenesis in the zoonotic pathogen Chlamydia caviae.PLoS One2019
31386347Insights into the Autoproteolytic Processing and Catalytic Mechanism of the <i>Chlamydia trachomatis</i> Virulence-Associated Protease CPAF.Biochemistry2019
31249676A renewed tool kit to explore <i>Chlamydia</i> pathogenesis: from molecular genetics to new infection models.F1000Res2019
31024512Ptr/CTL0175 Is Required for the Efficient Recovery of <i>Chlamydia trachomatis</i> From Stress Induced by Gamma-Interferon.Front Microbiol2019
29513221Site-specific glycosylation regulates the form and function of the intermediate filament cytoskeleton.Elife2018
30092202An Atlas of Genetic Variation Linking Pathogen-Induced Cellular Traits to Human Disease.Cell Host Microbe2018
30297356The Expanding Molecular Genetics Tool Kit in Chlamydia.J Bacteriol2018
30397340A Chlamydia effector combining deubiquitination and acetylation activities induces Golgi fragmentation.Nat Microbiol2018
30619180Chlamydia Persistence: A Survival Strategy to Evade Antimicrobial Effects in-vitro and in-vivo.Front Microbiol2018
28041929The Chlamydia trachomatis Inclusion Membrane Protein CpoS Counteracts STING-Mediated Cellular Surveillance and Suicide Programs.Cell Host Microbe2017
28357396<i>Chlamydia trachomatis</i>' struggle to keep its host alive.Microb Cell2017
28988619Bacterial Subversion of COG-Dependent Membrane Traffic.Trends Cell Biol2017
28515151Assessing the satisfaction and burden within an academic animal care and use program.FASEB J2017
28784680N-Acylated Derivatives of Sulfamethoxazole Block Chlamydia Fatty Acid Synthesis and Interact with FabF.Antimicrob Agents Chemother2017
28626230Engineering of obligate intracellular bacteria: progress, challenges and paradigms.Nat Rev Microbiol2017
28744480The Effector TepP Mediates Recruitment and Activation of Phosphoinositide 3-Kinase on Early <i>Chlamydia trachomatis</i> Vacuoles.mSphere2017
27030552Emancipating Chlamydia: Advances in the Genetic Manipulation of a Recalcitrant Intracellular Pathogen.Microbiol Mol Biol Rev2016
27607551Molecular Genetic Analysis of Chlamydia Species.Annu Rev Microbiol2016
27911803Genomic sequencing-based mutational enrichment analysis identifies motility genes in a genetically intractable gut microbe.Proc Natl Acad Sci U S A2016
27382018The Chlamydia-Secreted Protease CPAF Promotes Chlamydial Survival in the Mouse Lower Genital Tract.Infect Immun2016
26829550The Chlamydia trachomatis Protease CPAF Contains a Cryptic PDZ-Like Domain with Similarity to Human Cell Polarity and Tight Junction PDZ-Containing Proteins.PLoS One2016
27006461Discovery of the Elusive UDP-Diacylglucosamine Hydrolase in the Lipid A Biosynthetic Pathway in Chlamydia trachomatis.mBio2016
25422265Coxiella burnetii effector proteins that localize to the parasitophorous vacuole membrane promote intracellular replication.Infect Immun2015
26426122Differential Translocation of Host Cellular Materials into the Chlamydia trachomatis Inclusion Lumen during Chemical Fixation.PLoS One2015
26424482A Chlamydia trachomatis strain with a chemically generated amino acid substitution (P370L) in the cthtrA gene shows reduced elementary body production.BMC Microbiol2015
26118995Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection.Cell Host Microbe2015
25920978Integrating chemical mutagenesis and whole-genome sequencing as a platform for forward and reverse genetic analysis of Chlamydia.Cell Host Microbe2015
25909443Chlamydia trachomatis Infection Leads to Defined Alterations to the Lipid Droplet Proteome in Epithelial Cells.PLoS One2015
24626843Cell biology at the host-microbe interface.Mol Biol Cell2014
25550323A 2-pyridone-amide inhibitor targets the glucose metabolism pathway of Chlamydia trachomatis.mBio2014
25313403Raphael Valdivia: how Chlamydia settles in.J Cell Biol2014
25172291A chemical mutagenesis approach to identify virulence determinants in the obligate intracellular pathogen Chlamydia trachomatis.Methods Mol Biol2014
25184567Search for microRNAs expressed by intracellular bacterial pathogens in infected mammalian cells.PLoS One2014
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Collaborators

Joe Dan Dunn
University of Geneva
Co-authored papers 5
Stephen Walsh
Co-authored papers 2
Gregory M Barton
University of California berkeley
Co-authored papers 2
Cherilyn A Elwell
University of California san francisco
Co-authored papers 2
Anusha M Gopalakrishnan
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Co-authored papers 2
Martin A Moseley
Center for Genomic and Computational Biology
Co-authored papers 2
Joanne N Engel
University of California san francisco
Co-authored papers 2
Christopher B Newgard
Duke Molecular Physiology Institute
Co-authored papers 1
Heather Gordish-Dressman
Co-authored papers 1
Christian R H Raetz
Co-authored papers 1
Nevan J Krogan (CM4AI)
University of California San Francisco
Co-authored papers 1
Jessica Sherry
University of California San Francisco
Co-authored papers 1
Michael N Starnbach
Harvard Medical School
Co-authored papers 1
Gail P Jarvik
University of Washington Medical Center
Co-authored papers 1
Jeffrey R Johnson
Gladstone Institutes
Co-authored papers 1
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University of Virginia School of Medicine
Co-authored papers 1
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Co-authored papers 1
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Institute of Molecular Biosciences, Goethe University Frankfurt
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University of California san francisco
Co-authored papers 1
Elizabeth R Fischer
National Institute of Allergy and Infectious Diseases, National Institutes of Health
Co-authored papers 1
Erik Verschueren
University of California San Francisco
Co-authored papers 1
Natali Gulbahce
Complete Genomics Inc.
Co-authored papers 1
Jennifer A Wargo
Co-authored papers 1
Joshua C Denny
Vanderbilt University
Co-authored papers 1
Bennett H Penn
University of California Davis
Co-authored papers 1
Ziqiang Guan
Duke University Medical Center
Co-authored papers 1
Andrew Frando
Seattle Children's Research Institute
Co-authored papers 1
Kathleen M Mirrashidi
Genentech Inc.
Co-authored papers 1
Ian B Stanaway
Kidney Research Institute and Division of Nephrology, University of Washington
Co-authored papers 1
Ryan Balfour Sartor
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Release 1.2