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Author Details

Jacques Drouin
Institut de recherches cliniques de Montreal (IRCM)
1974
177
71
PMIDPaper TitleJournal TitlePublished Year
37326021Chromatin opening ability of pioneer factor Pax7 depends on unique isoform and C-terminal domain.Nucleic Acids Res2023
37740118Pioneer factors - key regulators of chromatin and gene expression.Nat Rev Genet2023
35264768Pioneer factors as master regulators of the epigenome and cell fate.Nat Rev Mol Cell Biol2022
35524583The corticotroph cells from early development to tumorigenesis.J Neuroendocrinol2022
33112269MECHANISMS IN ENDOCRINOLOGY: Pioneer transcription factors in pituitary development and tumorigenesis.Eur J Endocrinol2021
34035267Control of mouse limb initiation and antero-posterior patterning by Meis transcription factors.Nat Commun2021
34197620Pax7 pioneer factor action requires both paired and homeo DNA binding domains.Nucleic Acids Res2021
32427842HOX13-dependent chromatin accessibility underlies the transition towards the digit development program.Nat Commun2020
31444346Pioneer and nonpioneer factor cooperation drives lineage specific chromatin opening.Nat Commun2019
31481663Pituitary cell translation and secretory capacities are enhanced cell autonomously by the transcription factor Creb3l2.Nat Commun2019
29507097Pioneer transcription factors shape the epigenetic landscape.J Biol Chem2018
30106373The role of Pitx2 and Pitx3 in muscle stem cells gives new insights into P38α MAP kinase and redox regulation of muscle regeneration.Elife2018
29358650Pioneer factor Pax7 deploys a stable enhancer repertoire for specification of cell fate.Nat Genet2018
29490982Regulatory integration of Hox factor activity with T-box factors in limb development.Development2018
29705333Shh signaling influences the phenotype of Pitx1-/- hindlimbs.Dev Biol2018
27514757Specificity of Pitx3-Dependent Gene Regulatory Networks in Subsets of Midbrain Dopamine Neurons.Mol Neurobiol2017
28807899<i>Pitx1</i> directly modulates the core limb development program to implement hindlimb identity.Development2017
28533356Loss-of-function mutations in the <i>CABLES1</i> gene are a novel cause of Cushing's disease.Endocr Relat Cancer2017
26695862The Cables1 Gene in Glucocorticoid Regulation of Pituitary Corticotrope Growth and Cushing Disease.J Clin Endocrinol Metab2016
27974206Distal Limb Patterning Requires Modulation of cis-Regulatory Activities by HOX13.Cell Rep2016
27997829Redox Regulation by Pitx2 and Pitx3 Is Critical for Fetal Myogenesis.Dev Cell2016
2679282860 YEARS OF POMC: Transcriptional and epigenetic regulation of POMC gene expression.J Mol Endocrinol2016
25956343Expression and clinical relevance of paired box protein 7 and sex determining region Y-box 2 in canine corticotroph pituitary adenomas.Vet J2015
26234816Pax factors in transcription and epigenetic remodelling.Semin Cell Dev Biol2015
24871946Redox regulation by Pitx2 and Pitx3 is critical for fetal myogenesis.Dev Cell2014
26461356Pitx2 and Pitx3 transcription factors: two key regulators of the redox state in adult skeletal muscle stem cells and muscle regeneration.Free Radic Biol Med2014
25501001Rgs6 is required for adult maintenance of dopaminergic neurons in the ventral substantia nigra.PLoS Genet2014
25524009Mutations in NFKB2 and potential genetic heterogeneity in patients with DAVID syndrome, having variable endocrine and immune deficiencies.BMC Med Genet2014
24825399Minireview: pioneer transcription factors in cell fate specification.Mol Endocrinol2014
22524684Characterization of MENX-associated pituitary tumours.Neuropathol Appl Neurobiol2013
23754801Adult pituitary cell maintenance: lineage-specific contribution of self-duplication.Mol Endocrinol2013
23331067The transcription factor Pitx3 is expressed selectively in midbrain dopaminergic neurons susceptible to neurodegenerative stress.J Neurochem2013
22170728Phenotypic homogeneity and genotypic variability in a large series of congenital isolated ACTH-deficiency patients with TPIT gene mutations.J Clin Endocrinol Metab2012
23042945The side population phenomenon enriches for designated adrenocortical progenitor cells in mice.J Endocrinol2012
23070814The selector gene Pax7 dictates alternate pituitary cell fates through its pioneer action on chromatin remodeling.Genes Dev2012
22436593A tridimensional view of pituitary development and function.Trends Endocrinol Metab2012
22633955The Stat3/GR interaction code: predictive value of direct/indirect DNA recruitment for transcription outcome.Mol Cell2012
21193556A pituitary-specific enhancer of the POMC gene with preferential activity in corticotrope cells.Mol Endocrinol2011
21622576The Ets factor Etv1 interacts with Tpit protein for pituitary pro-opiomelanocortin (POMC) gene transcription.J Biol Chem2011
21746936Related pituitary cell lineages develop into interdigitated 3D cell networks.Proc Natl Acad Sci U S A2011
21752888Severe cortisol deficiency associated with reversible growth hormone deficiency in two infants: what is the link?J Clin Endocrinol Metab2011
21423243Autoimmunity: acquired versus inherited pituitary deficiency - same difference?Nat Rev Endocrinol2011
20616491Stem cells, differentiation and cell cycle control in pituitary.Front Horm Res2010
20978076Pitx2 defines alternate pathways acting through MyoD during limb and somitic myogenesis.Development2010
20975709Divergent transcriptional activities determine limb identity.Nat Commun2010
20660298Cooperation between cyclin E and p27(Kip1) in pituitary tumorigenesis.Mol Endocrinol2010
19321449TIF1beta/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77.J Biol Chem2009
19139274Distinct developmental roles of cell cycle inhibitors p57Kip2 and p27Kip1 distinguish pituitary progenitor cell cycle exit from cell cycle reentry of differentiated cells.Mol Cell Biol2009
17544240Expression and mutation analysis of Tpit in the canine pituitary gland and corticotroph adenomas.Domest Anim Endocrinol2008
18927629Regulatory network analyses reveal genome-wide potentiation of LIF signaling by glucocorticoids and define an innate cell defense response.PLoS Genet2008
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Collaborators

David Langlais
McGill University
Co-authored papers 6
Dominique Figarella-Branger
Co-authored papers 5
Bart Barrell
Wellcome Trust Sanger Institute
Co-authored papers 3
Tomi Pastinen
Co-authored papers 2
Deepak Jain
Co-authored papers 2
Michel L Tremblay
Co-authored papers 2
Patrice Mollard
Institute of Functional Genomics, University of Montpellier, CNRS, INSERM
Co-authored papers 2
Hoonkyo Suh
Cleveland Clinic
Co-authored papers 2
Fran??ois Guillemot
the Francis Crick Institute
Co-authored papers 1
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University of Minnesota
Co-authored papers 1
Christoph Klein
Kinderklinik und Kinderpoliklinik der Ludwig-Maximilians-Universitat Munchen
Co-authored papers 1
Peter White
The Ohio State University
Co-authored papers 1
Gordon L Hager
National Cancer Institute, National Institutes of Health
Co-authored papers 1
Christopher V E Wright
Vanderbilt University
Co-authored papers 1
Richard H Goodman
Vollum Institute, Oregon Health & Science University
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Lund University
Co-authored papers 1
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 1
Athanasios Arsenlis
Lawrence Livermore National Laboratory
Co-authored papers 1
Mehul T Dattani
Great Ormond Street Hospital for Children NHS Foundation Trust
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Klaus H Kaestner
Department of Genetics and Institute for Diabetes, University of Pennsylvania
Co-authored papers 1
David J Hodson
Institute of Metabolism and Systems Research (IMSR), University of Birmingham
Co-authored papers 1
Robert J Lefkowitz
Co-authored papers 1
Iros Barozzi
Co-authored papers 1
Jussi Taipale
Co-authored papers 1
Michael Karin
Co-authored papers 1
Axel Visel
Co-authored papers 1
David M Keller
California State University Chico
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Haiyan Wang
Roche Pharma Research and Early Development, F. Hoffmann-La Roche Ltd
Co-authored papers 1
Vincent Laudet
Okinawa Institute of Science and Technology
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