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Author Details

Ning Zheng
University of Washington
1996
156
57
Andrej Sali (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36200388Loss-of-function variants in MYCBP2 cause neurobehavioural phenotypes and corpus callosum defects.Brain2023
37903281Structural basis for severe pain caused by mutations in the voltage sensors of sodium channel NaV1.7.J Gen Physiol2023
36996107Structural basis for severe pain caused by mutations in the S4-S5 linkers of voltage-gated sodium channel Na<sub>V</sub>1.7.Proc Natl Acad Sci U S A2023
36478090Analyses of Cullin1 homologs reveal functional redundancy in S-RNase-based self-incompatibility and evolutionary relationships in eudicots.Plant Cell2023
36938583Total chemical synthesis of sumoylated histone H4 reveals negative biochemical crosstalk with histone ubiquitylation.Chem Commun (Camb)2023
34862481The NSP14/NSP10 RNA repair complex as a Pan-coronavirus therapeutic target.Cell Death Differ2022
36124979INOSITOL (1,3,4) TRIPHOSPHATE 5/6 KINASE1-dependent inositol polyphosphates regulate auxin responses in Arabidopsis.Plant Physiol2022
36116709Targeting prolyl isomerase Pin1 as a promising strategy to overcome resistance to cancer therapies.Pharmacol Res2022
35089787Two diphosphorylated degrons control c-Myc degradation by the Fbw7 tumor suppressor.Sci Adv2022
35145136Defining molecular glues with a dual-nanobody cannabidiol sensor.Nat Commun2022
33232657Structural Basis for High-Affinity Trapping of the Na<sub>V</sub>1.7 Channel in Its Resting State by Tarantula Toxin.Mol Cell2021
33602808Inhibitors of cullin-RING E3 ubiquitin ligase 4 with antitumor potential.Proc Natl Acad Sci U S A2021
33610718Regulatory mechanisms and therapeutic targeting of vasculogenic mimicry in hepatocellular carcinoma.Pharmacol Res2021
34642294NOL7 facilitates melanoma progression and metastasis.Signal Transduct Target Ther2021
34520724Open-state structure and pore gating mechanism of the cardiac sodium channel.Cell2021
34430612MiR-519d-5p modulates the sensitivity of breast cancer to chemotherapy by forming a negative feedback loop with RELA.Ann Transl Med2021
34075876Repression by the <i>Arabidopsis</i> TOPLESS corepressor requires association with the core mediator complex.Elife2021
34099183Expression and purification of the cardiac sodium channel Na<sub>V</sub>1.5 for cryo-EM structure determination.Methods Enzymol2021
34256050Beyond PKA: Evolutionary and structural insights that define a docking and dimerization domain superfamily.J Biol Chem2021
33428809Regorafenib inhibits migration, invasion, and vasculogenic mimicry of hepatocellular carcinoma via targeting ID1-mediated EMT.Mol Carcinog2021
33397917Structural basis for voltage-sensor trapping of the cardiac sodium channel by a deathstalker scorpion toxin.Nat Commun2021
33477218[Population status and protection evaluation of <i>Syzygium album,</i> a species with extremely small population.]Ying Yong Sheng Tai Xue Bao2021
32126207FBXL5 Regulates IRP2 Stability in Iron Homeostasis via an Oxygen-Responsive [2Fe2S] Cluster.Mol Cell2020
31898219Structural Biology of CRL Ubiquitin Ligases.Adv Exp Med Biol2020
31866066Structure of the Cardiac Sodium Channel.Cell2020
32047135Structure of an Inner Membrane Protein Required for PhoPQ-Regulated Increases in Outer Membrane Cardiolipin.mBio2020
32047038Basis for metabolite-dependent Cullin-RING ligase deneddylation by the COP9 signalosome.Proc Natl Acad Sci U S A2020
32101164Dynamics at the serine loop underlie differential affinity of cryptochromes for CLOCK:BMAL1 to control circadian timing.Elife2020
32034103Structural dynamics of the human COP9 signalosome revealed by cross-linking mass spectrometry and integrative modeling.Proc Natl Acad Sci U S A2020
33199904The conformational cycle of a prototypical voltage-gated sodium channel.Nat Chem Biol2020
32788727Structural basis of salicylic acid perception by Arabidopsis NPR proteins.Nature2020
30510035Molecular dissection of multiphase inactivation of the bacterial sodium channel Na<sub>V</sub>Ab.J Gen Physiol2019
31701716[Effects of different intensity interval exercise of 6 weeks on body composition of obese rats].Zhongguo Ying Yong Sheng Li Xue Za Zhi2019
31733991Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS.Mol Cell2019
30117392The Evaluation of Animal Models in the Development of Anticancer Agents: From Preclinical to Clinical Tests.Curr Cancer Drug Targets2019
30259564CXCR7 is not obligatory for CXCL12-CXCR4-induced epithelial-mesenchymal transition in human ovarian cancer.Mol Carcinog2019
31525912Degronomics: Mapping the Interacting Peptidome of a Ubiquitin Ligase Using an Integrative Mass Spectrometry Strategy.Anal Chem2019
31353218Resting-State Structure and Gating Mechanism of a Voltage-Gated Sodium Channel.Cell2019
31209342GGTase3 is a newly identified geranylgeranyltransferase targeting a ubiquitin ligase.Nat Struct Mol Biol2019
31235876Bipartite anchoring of SCREAM enforces stomatal initiation by coupling MAP kinases to SPEECHLESS.Nat Plants2019
31575922Scribble co-operatively binds multiple α<sub>1D</sub>-adrenergic receptor C-terminal PDZ ligands.Sci Rep2019
31619521The cysteine protease ApdS from <i>Streptococcus suis</i> promotes evasion of innate immune defenses by cleaving the antimicrobial peptide cathelicidin LL-37.J Biol Chem2019
31391290Structural Basis for Diltiazem Block of a Voltage-Gated Ca<sup>2+</sup> Channel.Mol Pharmacol2019
31151472Co-delivery of sorafenib and metapristone encapsulated by CXCR4-targeted PLGA-PEG nanoparticles overcomes hepatocellular carcinoma resistance to sorafenib.J Exp Clin Cancer Res2019
30946352The value of diffusion tensor imaging for differentiating autism spectrum disorder with language delay from developmental language disorder among toddlers.Medicine (Baltimore)2019
30968769HAMPT, A Novel Quadruple Drug Combination Designed for Cancer Metastatic Chemoprevention: From Hypothesis to Proof-of-concept.Curr Cancer Drug Targets2019
30791110The Antiresection Activity of the X Protein Encoded by Hepatitis Virus B.Hepatology2019
29545534Zinc knuckle of TAF1 is a DNA binding module critical for TFIID promoter occupancy.Sci Rep2018
29974686[Turbulence micro-meteorological characteristics over the plantation canopy.]Ying Yong Sheng Tai Xue Bao2018
30100181Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module.Cell2018
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Collaborators

William A Catterall
Co-authored papers 21
Haibin Mao
University of Washington Howard Hughes Medical Institute, University of Washington
Co-authored papers 18
Nikola P Pavletich
Memorial Sloan Kettering Cancer Center
Co-authored papers 7
Lan Huang
University of California Irvine
Co-authored papers 4
Stephane Angers
Department of Pharmaceutical Sciences, University of Toronto
Co-authored papers 3
Clinton Yu
University of California Irvine
Co-authored papers 3
Michael J MacCoss
University of Washington
Co-authored papers 3
Michael B Major
Washington University in St. Louis
Co-authored papers 3
Carol V Robinson
University of Oxford
Co-authored papers 2
Roberto Sanchez
Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai
Co-authored papers 2
Adolfo Saiardi
Co-authored papers 2
Henning J Jessen
Co-authored papers 2
Stephen J Elledge
Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 2
Scott D Rychnovsky
University of California irvine
Co-authored papers 2
Alan D D'Andrea
Dana-Farber Cancer Institute
Co-authored papers 2
John D Scott
University of Washington
Co-authored papers 1
Ignacia Echeverria
University of California san francisco
Co-authored papers 1
Josep Rizo
University of Texas Southwestern Medical Center
Co-authored papers 1
Timothy R Billiar
University of Pittsburgh
Co-authored papers 1
Seema R Lalani
Co-authored papers 1
Anne-Claude Gingras
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 1
David Neil Hayes
Center for Cancer Research, University of Tennessee Health Science Center
Co-authored papers 1
Craig B Gutierrez
University of California irvine
Co-authored papers 1
Ernest Fraenkel
Co-authored papers 1
Junhong Han
West China Hospital, Sichuan University
Co-authored papers 1
Weiqi Chen
Big Data Decision Institute, Jinan University
Co-authored papers 1
Sarah A Block
University of California irvine
Co-authored papers 1
Samanta Capolicchio
Co-authored papers 1
Solomon H Snyder
Co-authored papers 1
Fowzan S Alkuraya
King Faisal Specialist Hospital and Research Center
Co-authored papers 1
Release 1.2