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Author Details
Full Name
Francesca M Buffa
Affiliation
University of Oxford
ORCID
Career Start Year
1998
Papers
146
H Index
48
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
36539575
WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma.
Cell Oncol (Dordr)
2023
37528416
A role for SETD2 loss in tumorigenesis through DNA methylation dysregulation.
BMC Cancer
2023
38047081
A machine learning and directed network optimization approach to uncover <i>TP53</i> regulatory patterns.
iScience
2023
37392899
The impact of survivorship bias in glioblastoma research.
Crit Rev Oncol Hematol
2023
36951111
Homologous recombination suppresses transgenerational DNA end resection and chromosomal instability in fission yeast.
Nucleic Acids Res
2023
36352216
Machine Learning Using Gene-Sets to Infer miRNA Function.
Adv Exp Med Biol
2022
35771179
The MITF regulatory network in melanoma.
Pigment Cell Melanoma Res
2022
35379950
Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation.
Cell Death Differ
2022
35581637
Radiogenomic analysis of primary breast cancer reveals [18F]-fluorodeoxglucose dynamic flux-constants are positively associated with immune pathways and outperform static uptake measures in associating with glucose metabolism.
Breast Cancer Res
2022
35764612
Liver glycogen phosphorylase is upregulated in glioblastoma and provides a metabolic vulnerability to high dose radiation.
Cell Death Dis
2022
35848459
Endothelial cell death after ionizing radiation does not impair vascular structure in mouse tumor models.
EMBO Rep
2022
36068142
Single cell RNA-sequencing: A powerful yet still challenging technology to study cellular heterogeneity.
Bioessays
2022
36038791
Obesity: a perfect storm for carcinogenesis.
Cancer Metastasis Rev
2022
36093876
New perspectives in liquid biopsy for glioma patients.
Curr Opin Oncol
2022
32591342
Heritable genetic variants in key cancer genes link cancer risk with anthropometric traits.
J Med Genet
2021
33597271
Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non-Small Cell Lung Cancer.
Clin Cancer Res
2021
33964942
Interferon- and STING-independent induction of type I interferon stimulated genes during fractionated irradiation.
J Exp Clin Cancer Res
2021
34348993
ADGRL4/ELTD1 Expression in Breast Cancer Cells Induces Vascular Normalization and Immune Suppression.
Mol Cancer Res
2021
34099545
Defining T Cell Subsets in Human Tonsils Using ChipCytometry.
J Immunol
2021
34197599
Replication catastrophe induced by cyclic hypoxia leads to increased APOBEC3B activity.
Nucleic Acids Res
2021
34140498
Hypoxia-induced SETX links replication stress with the unfolded protein response.
Nat Commun
2021
32789015
Correction to: Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells.
Cancer Metab
2020
31819193
Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin.
Br J Cancer
2020
32692762
The mevalonate precursor enzyme HMGCS1 is a novel marker and key mediator of cancer stem cell enrichment in luminal and basal models of breast cancer.
PLoS One
2020
32576885
Role of gene signatures combined with pathology in classification of oropharynx head and neck cancer.
Sci Rep
2020
32647572
Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells.
Cancer Metab
2020
30385313
Endogenous miRNA sponges mediate the generation of oscillatory dynamics for a non-coding RNA network.
J Theor Biol
2019
31207090
MITF controls the TCA cycle to modulate the melanoma hypoxia response.
Pigment Cell Melanoma Res
2019
31516745
Identification of anticancer drugs to radiosensitise <i>BRAF</i>-wild-type and mutant colorectal cancer.
Cancer Biol Med
2019
31424118
E2F1 proteolysis via SCF-cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition.
EMBO J
2019
30715320
Modeling genotypes in their microenvironment to predict single- and multi-cellular behavior.
Gigascience
2019
30975523
Science in Focus: Bioinformatics Part 1 - Lost in Translation.
Clin Oncol (R Coll Radiol)
2019
30885992
Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism.
Mol Cancer Res
2019
30971781
Guidelines for using sigQC for systematic evaluation of gene signatures.
Nat Protoc
2019
30485129
The many faces of mathematical modelling in oncology.
Br J Radiol
2019
29180477
miR-139-5p Modulates Radiotherapy Resistance in Breast Cancer by Repressing Multiple Gene Networks of DNA Repair and ROS Defense.
Cancer Res
2018
29986057
Nucleoporin 54 contributes to homologous recombination repair and post-replicative DNA integrity.
Nucleic Acids Res
2018
30244975
Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer.
Cell Metab
2018
30531873
Pan-cancer characterisation of microRNA across cancer hallmarks reveals microRNA-mediated downregulation of tumour suppressors.
Nat Commun
2018
29729848
Development and Validation of a 28-gene Hypoxia-related Prognostic Signature for Localized Prostate Cancer.
EBioMedicine
2018
29388947
Clinical whole-genome sequencing from routine formalin-fixed, paraffin-embedded specimens: pilot study for the 100,000 Genomes Project.
Genet Med
2018
29382819
RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73.
Nat Commun
2018
29739952
Translational study identifies XPF and MUS81 as predictive biomarkers for oxaliplatin-based peri-operative chemotherapy in patients with esophageal adenocarcinoma.
Sci Rep
2018
28001444
Vitamin D Receptor Expression in Plasmablastic Lymphoma and Myeloma Cells Confers Susceptibility to Vitamin D.
Endocrinology
2017
28400426
A Gene Signature for Selecting Benefit from Hypoxia Modification of Radiotherapy for High-Risk Bladder Cancer Patients.
Clin Cancer Res
2017
28494188
Depletion of signal recognition particle 72kDa increases radiosensitivity.
Cancer Biol Ther
2017
28096186
Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma.
Genes Dev
2017
28445154
Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth.
Oncotarget
2017
28972962
IGF-1R associates with adverse outcomes after radical radiotherapy for prostate cancer.
Br J Cancer
2017
28677687
TOPK modulates tumour-specific radiosensitivity and correlates with recurrence after prostate radiotherapy.
Br J Cancer
2017
1 - 50 of 146
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Collaborators
Adrian L Harris
University of Oxford
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University of Manchester
Co-authored papers
15
Syed Haider
Institute of Cancer Research
Co-authored papers
14
Jiannis Ragoussis
McGill University
Co-authored papers
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Carme Camps
National Institute for Health Research Biomedical Research Centre
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Wei-Chen Cheng
MRC Oxford Institute for Radiation Oncology & Biology, University of Oxford
Co-authored papers
8
Ruud G P M van Stiphout
University of Oxford
Co-authored papers
7
Colin R Goding
Ludwig Institute for Cancer Research, University of Oxford
Co-authored papers
4
Bradly G Wouters
Princess Margaret Cancer Centre, University Health Network and, University of Toronto
Co-authored papers
4
Fredrik Karpe
Co-authored papers
4
Mircea Ivan
Indiana University School of Medicine
Co-authored papers
3
Marianne Koritzinsky
Princess Margaret Cancer Centre University Health Network
Co-authored papers
3
Clare Verrill
NIHR Oxford Biomedical Research Centre
Co-authored papers
3
Peter Hoskin
Mount Vernon Cancer Centre
Co-authored papers
3
Emmanouil Fokas
Universityhospital Frankfurt
Co-authored papers
2
Anil K Sood
The University of Texas MD Anderson Cancer Center
Co-authored papers
2
Paul N Span
Radboud University Medical Center
Co-authored papers
2
Alexander Kanapin
Co-authored papers
2
Paul C Boutros
University of California los angeles
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2
Lingjian Yang
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