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Author Details

Francesca M Buffa
University of Oxford
1998
146
48
PMIDPaper TitleJournal TitlePublished Year
36539575WNT5A-ROR2 axis mediates VEGF dependence of BRAF mutant melanoma.Cell Oncol (Dordr)2023
37528416A role for SETD2 loss in tumorigenesis through DNA methylation dysregulation.BMC Cancer2023
38047081A machine learning and directed network optimization approach to uncover <i>TP53</i> regulatory patterns.iScience2023
37392899The impact of survivorship bias in glioblastoma research.Crit Rev Oncol Hematol2023
36951111Homologous recombination suppresses transgenerational DNA end resection and chromosomal instability in fission yeast.Nucleic Acids Res2023
36352216Machine Learning Using Gene-Sets to Infer miRNA Function.Adv Exp Med Biol2022
35771179The MITF regulatory network in melanoma.Pigment Cell Melanoma Res2022
35379950Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation.Cell Death Differ2022
35581637Radiogenomic analysis of primary breast cancer reveals [18F]-fluorodeoxglucose dynamic flux-constants are positively associated with immune pathways and outperform static uptake measures in associating with glucose metabolism.Breast Cancer Res2022
35764612Liver glycogen phosphorylase is upregulated in glioblastoma and provides a metabolic vulnerability to high dose radiation.Cell Death Dis2022
35848459Endothelial cell death after ionizing radiation does not impair vascular structure in mouse tumor models.EMBO Rep2022
36068142Single cell RNA-sequencing: A powerful yet still challenging technology to study cellular heterogeneity.Bioessays2022
36038791Obesity: a perfect storm for carcinogenesis.Cancer Metastasis Rev2022
36093876New perspectives in liquid biopsy for glioma patients.Curr Opin Oncol2022
32591342Heritable genetic variants in key cancer genes link cancer risk with anthropometric traits.J Med Genet2021
33597271Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non-Small Cell Lung Cancer.Clin Cancer Res2021
33964942Interferon- and STING-independent induction of type I interferon stimulated genes during fractionated irradiation.J Exp Clin Cancer Res2021
34348993ADGRL4/ELTD1 Expression in Breast Cancer Cells Induces Vascular Normalization and Immune Suppression.Mol Cancer Res2021
34099545Defining T Cell Subsets in Human Tonsils Using ChipCytometry.J Immunol2021
34197599Replication catastrophe induced by cyclic hypoxia leads to increased APOBEC3B activity.Nucleic Acids Res2021
34140498Hypoxia-induced SETX links replication stress with the unfolded protein response.Nat Commun2021
32789015Correction to: Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells.Cancer Metab2020
31819193Transcriptomic analysis of human primary breast cancer identifies fatty acid oxidation as a target for metformin.Br J Cancer2020
32692762The mevalonate precursor enzyme HMGCS1 is a novel marker and key mediator of cancer stem cell enrichment in luminal and basal models of breast cancer.PLoS One2020
32576885Role of gene signatures combined with pathology in classification of oropharynx head and neck cancer.Sci Rep2020
32647572Disruption of hypoxia-inducible fatty acid binding protein 7 induces beige fat-like differentiation and thermogenesis in breast cancer cells.Cancer Metab2020
30385313Endogenous miRNA sponges mediate the generation of oscillatory dynamics for a non-coding RNA network.J Theor Biol2019
31207090MITF controls the TCA cycle to modulate the melanoma hypoxia response.Pigment Cell Melanoma Res2019
31516745Identification of anticancer drugs to radiosensitise <i>BRAF</i>-wild-type and mutant colorectal cancer.Cancer Biol Med2019
31424118E2F1 proteolysis via SCF-cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition.EMBO J2019
30715320Modeling genotypes in their microenvironment to predict single- and multi-cellular behavior.Gigascience2019
30975523Science in Focus: Bioinformatics Part 1 - Lost in Translation.Clin Oncol (R Coll Radiol)2019
30885992Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism.Mol Cancer Res2019
30971781Guidelines for using sigQC for systematic evaluation of gene signatures.Nat Protoc2019
30485129The many faces of mathematical modelling in oncology.Br J Radiol2019
29180477miR-139-5p Modulates Radiotherapy Resistance in Breast Cancer by Repressing Multiple Gene Networks of DNA Repair and ROS Defense.Cancer Res2018
29986057Nucleoporin 54 contributes to homologous recombination repair and post-replicative DNA integrity.Nucleic Acids Res2018
30244975Integrated Pharmacodynamic Analysis Identifies Two Metabolic Adaption Pathways to Metformin in Breast Cancer.Cell Metab2018
30531873Pan-cancer characterisation of microRNA across cancer hallmarks reveals microRNA-mediated downregulation of tumour suppressors.Nat Commun2018
29729848Development and Validation of a 28-gene Hypoxia-related Prognostic Signature for Localized Prostate Cancer.EBioMedicine2018
29388947Clinical whole-genome sequencing from routine formalin-fixed, paraffin-embedded specimens: pilot study for the 100,000 Genomes Project.Genet Med2018
29382819RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73.Nat Commun2018
29739952Translational study identifies XPF and MUS81 as predictive biomarkers for oxaliplatin-based peri-operative chemotherapy in patients with esophageal adenocarcinoma.Sci Rep2018
28001444Vitamin D Receptor Expression in Plasmablastic Lymphoma and Myeloma Cells Confers Susceptibility to Vitamin D.Endocrinology2017
28400426A Gene Signature for Selecting Benefit from Hypoxia Modification of Radiotherapy for High-Risk Bladder Cancer Patients.Clin Cancer Res2017
28494188Depletion of signal recognition particle 72kDa increases radiosensitivity.Cancer Biol Ther2017
28096186Translation reprogramming is an evolutionarily conserved driver of phenotypic plasticity and therapeutic resistance in melanoma.Genes Dev2017
28445154Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth.Oncotarget2017
28972962IGF-1R associates with adverse outcomes after radical radiotherapy for prostate cancer.Br J Cancer2017
28677687TOPK modulates tumour-specific radiosensitivity and correlates with recurrence after prostate radiotherapy.Br J Cancer2017
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Collaborators

University of Oxford
Co-authored papers 74
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Co-authored papers 15
Institute of Cancer Research
Co-authored papers 14
McGill University
Co-authored papers 14
National Institute for Health Research Biomedical Research Centre
Co-authored papers 8
MRC Oxford Institute for Radiation Oncology & Biology, University of Oxford
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University of Oxford
Co-authored papers 7
Ludwig Institute for Cancer Research, University of Oxford
Co-authored papers 4
Princess Margaret Cancer Centre, University Health Network and, University of Toronto
Co-authored papers 4
Co-authored papers 4
Indiana University School of Medicine
Co-authored papers 3
Princess Margaret Cancer Centre University Health Network
Co-authored papers 3
NIHR Oxford Biomedical Research Centre
Co-authored papers 3
Mount Vernon Cancer Centre
Co-authored papers 3
Universityhospital Frankfurt
Co-authored papers 2
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Radboud University Medical Center
Co-authored papers 2
Co-authored papers 2
University of California los angeles
Co-authored papers 2
Ankang University
Co-authored papers 2
Maastricht University
Co-authored papers 2
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Ontario Institute for Cancer Research
Co-authored papers 2
The University of Sheffield
Co-authored papers 2
University of Basel and University Hospital Basel
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Hospital for Sick Children
Co-authored papers 2
Co-authored papers 2
University of Manchester and The Christie NHS Foundation Trust
Co-authored papers 2
The Royal Marsden NHS Foundation Trust and Institute of Cancer Research
Co-authored papers 1