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Author Details

Fu-Yue Zeng
Sanford Burnham Prebys Medical Discovery Institute
1991
48
22
PMIDPaper TitleJournal TitlePublished Year
37995979High-throughput screening of compounds targeting RNA editing in Trypanosoma brucei: Novel molecular scaffolds with broad trypanocidal effects.Biochem Pharmacol2024
35731062Effect of rehabilitation on the long-term efficacy of botulinum toxin-A for spastic cerebral palsy.Eur Rev Med Pharmacol Sci2022
33414172Serine-Threonine Kinase TAO3-Mediated Trafficking of Endosomes Containing the Invadopodia Scaffold TKS5α Promotes Cancer Invasion and Tumor Growth.Cancer Res2021
33922601Development of a Robust High-Throughput Screening Platform for Inhibitors of the Striatal-Enriched Tyrosine Phosphatase (STEP).Int J Mol Sci2021
30771432Identification and characterization of small molecule inhibitors of the ubiquitin ligases Siah1/2 in melanoma and prostate cancer cells.Cancer Lett2019
26265713Cell-Based High-Throughput Luciferase Reporter Gene Assays for Identifying and Profiling Chemical Modulators of Endoplasmic Reticulum Signaling Protein, IRE1.J Biomol Screen2015
24870016Ultra-High-Throughput Screening of Natural Product Extracts to Identify Proapoptotic Inhibitors of Bcl-2 Family Proteins.J Biomol Screen2014
23527084Identification of small molecule activators of BMP signaling.PLoS One2013
23010269Discovery of 4-oxo-6-((pyrimidin-2-ylthio)methyl)-4H-pyran-3-yl 4-nitrobenzoate (ML221) as a functional antagonist of the apelin (APJ) receptor.Bioorg Med Chem Lett2012
19995556Glycogen synthase kinase 3 regulates PAX3-FKHR-mediated cell proliferation in human alveolar rhabdomyosarcoma cells.Biochem Biophys Res Commun2010
20797618Modulation of pantothenate kinase 3 activity by small molecules that interact with the substrate/allosteric regulatory domain.Chem Biol2010
19442434PAX3-FKHR sensitizes human alveolar rhabdomyosarcoma cells to camptothecin-mediated growth inhibition and apoptosis.Cancer Lett2009
18784074Cyclin-dependent kinase 2 negatively regulates human pregnane X receptor-mediated CYP3A4 gene expression in HepG2 liver carcinoma cells.J Biol Chem2008
12750375Random mutagenesis of the M3 muscarinic acetylcholine receptor expressed in yeast. Identification of point mutations that "silence" a constitutively active mutant M3 receptor and greatly impair receptor/G protein coupling.J Biol Chem2003
14645678Ligand specific up-regulation of a Renilla reniformis luciferase-tagged, structurally unstable muscarinic M3 chimeric G protein-coupled receptor.Mol Pharmacol2003
12181453Generation and analysis of constitutively active and physically destabilized mutants of the human beta(1)-adrenoceptor.Mol Pharmacol2002
10828795Correlation of galectin-3/galectin-3-binding sites with low differentiation status in head and neck squamous cell carcinomas.Otolaryngol Head Neck Surg2000
11008064Molecular aspects of muscarinic receptor dimerization.Neuropsychopharmacology2000
11064812Integrated nuclear fluorescence and expression of hormone-binding sites in malignant pleural effusions.Anal Quant Cytol Histol2000
10069496Structure-function analysis of muscarinic receptors and their associated G proteins.Life Sci1999
10349850Conserved extracellular cysteine pair in the M3 muscarinic acetylcholine receptor is essential for proper receptor cell surface localization but not for G protein coupling.J Neurochem1999
10347230Use of a disulfide cross-linking strategy to study muscarinic receptor structure and mechanisms of activation.J Biol Chem1999
10383466Identification and molecular characterization of m3 muscarinic receptor dimers.J Biol Chem1999
10425545Detection of sarcolectin-specific receptors like the cytokine macrophage migration inhibitory factor in rheumatoid nodules.Histol Histopathol1999
9739414Association of prognosis in surgically treated lung cancer patients with cytometric, histometric and ligand histochemical properties: with an emphasis on structural entropy.Anal Quant Cytol Histol1998
9651394Functional characterization of a series of mutant G protein alphaq subunits displaying promiscuous receptor coupling properties.J Biol Chem1998
9705864A specific antibody to the carbohydrate recognition domain of the asialoglycoprotein receptor RHL1 subunit does not react with RHL2/3 but blocks ligand binding.Biochem Biophys Res Commun1998
9789820Structure-function analysis of muscarinic acetylcholine receptors.J Physiol Paris1998
9224559Preneoplasia-associated expression of calcyclin and of binding sites for synthetic blood group A/H trisaccharide--exposing neoglycoconjugates in human lung.Cancer Biochem Biophys1997
8573155The human asialoglycoprotein receptor is palmitoylated and fatty deacylation causes inactivation of state 2 receptors.Biochem Biophys Res Commun1996
8943311Fatty acylation of the rat and human asialoglycoprotein receptors. A conserved cytoplasmic cysteine residue is acylated in all receptor subunits.J Biol Chem1996
8724132Renaturation and ligand blotting of the major subunit of the rat asialoglycoprotein receptor after denaturing polyacrylamide gel electrophoresis.Glycobiology1996
7673174Fatty acylation of the rat asialoglycoprotein receptor. The three subunits from active receptors contain covalently bound palmitate and stearate.J Biol Chem1995
28306129Developmental regulation of presence of binding sites for neoglycoproteins and endogenous lectins in various embryonic stages of human lung, liver and heart.Rouxs Arch Dev Biol1995
8593259Differential expression of calcyclin and its accessible ligands in various types of cutaneous tumors.J Dermatol Sci1995
7770063Differential response of the epidermal growth factor receptor tyrosine kinase activity to several plant and mammalian lectins.Mol Cell Biochem1995
7673175Hydroxylamine treatment differentially inactivates purified rat hepatic asialoglycoprotein receptors and distinguishes two receptor populations.J Biol Chem1995
7980871Migration inhibitory factor-binding sarcolectin from human placenta is indistinguishable from a subfraction of human serum albumin.Biol Chem Hoppe Seyler1994
8080681Correlation of expression of binding sites for synthetic blood group A-, B- and H-trisaccharides and for sarcolectin with survival of patients with bronchial carcinoma.Eur J Cancer1994
8166748Characterization of the macrophage migration inhibitory factor-binding site of sarcolectin and its relationship to human serum albumin.Biochem Biophys Res Commun1994
7683862The major binding protein of the interferon antagonist sarcolectin in human placenta is a macrophage migration inhibitory factor.Arch Biochem Biophys1993
8365543Identification of annexin II, annexin VI and glyceraldehyde-3-phosphate dehydrogenase as calcyclin-binding proteins in bovine heart.Int J Biochem1993
8302732Detection of the lymphokine migration inhibitory factor in normal and disease-affected lung by antibody and by its major binding protein, the interferon antagonist sarcolectin.Pathol Res Pract1993
8130170Alteration of human lung parenchyma associated with primary biliary cirrhosis.Zentralbl Pathol1993
1377469Mammalian fetuin-binding proteins sarcolectin, aprotinin and calcyclin display differences in their apparent carbohydrate specificity.Biochem Int1992
1644214Purification and properties of a fucoidan-binding protein from human placenta and its identification as immunoglobulin G.Int J Biochem1992
1449590Sialic acid-binding proteins: characterization, biological function and application.Z Naturforsch C J Biosci1992
1716875Carbohydrate-binding specificity of calcyclin and its expression in human tissues and leukemic cells.Arch Biochem Biophys1991
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Collaborators

Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 5
St. Jude Children's Research Hospital
Co-authored papers 5
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Co-authored papers 3
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Co-authored papers 3
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 3
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 3
Co-authored papers 3
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 2
St. Jude Children's Research Hospital
Co-authored papers 1
Oregon Health & Science University
Co-authored papers 1
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
Oregon Health and Science University
Co-authored papers 1
Oregon Health and Science University
Co-authored papers 1
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
University of British Columbia
Co-authored papers 1
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
St. Jude Children's Research Hospital
Co-authored papers 1
Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
Oregon Health & Science University, University of California Berkeley
Co-authored papers 1
Knight Cancer Institute, Oregon Health and Science University
Co-authored papers 1
Cancer Center, Sanford Burnham Prebys Medical Discovery Institute
Co-authored papers 1
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Chugai Pharmaceutical Co.
Co-authored papers 1
IRCCS Humanitas Research Hospital
Co-authored papers 1