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Author Details

Dorit Trudler
Tel Aviv University
2010
26
17
PMIDPaper TitleJournal TitlePublished Year
36175661Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection.Nat Chem Biol2023
37496076Physiological expression of mutated TAU impaired astrocyte activity and exacerbates β-amyloid pathology in 5xFAD mice.J Neuroinflammation2023
35052628Potential Therapeutic Use of the Rosemary Diterpene Carnosic Acid for Alzheimer's Disease, Parkinson's Disease, and Long-COVID through NRF2 Activation to Counteract the NLRP3 Inflammasome.Antioxidants (Basel)2022
35411336Targeted protein S-nitrosylation of ACE2 as potential treatment to prevent spread of SARS-CoV-2 infection.bioRxiv2022
36516243Mechanistic insight into female predominance in Alzheimer's disease based on aberrant protein S-nitrosylation of C3.Sci Adv2022
32467645NitroSynapsin ameliorates hypersynchronous neural network activity in Alzheimer hiPSC models.Mol Psychiatry2021
33483428α-Synuclein Oligomers Induce Glutamate Release from Astrocytes and Excessive Extrasynaptic NMDAR Activity in Neurons, Thus Contributing to Synapse Loss.J Neurosci2021
33833060Soluble α-synuclein-antibody complexes activate the NLRP3 inflammasome in hiPSC-derived microglia.Proc Natl Acad Sci U S A2021
34360966Emerging hiPSC Models for Drug Discovery in Neurodegenerative Diseases.Int J Mol Sci2021
34115964Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation.Immunity2021
31520492Alpha synuclein deficiency increases CD4<sup>+</sup> T-cells pro-inflammatory profile in a Nurr1-dependent manner.J Neurochem2020
30611669Novel Direct Conversion of Microglia to Neurons.Trends Mol Med2019
31782729Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs isogenic controls.Elife2019
30027906Parkinson's disease: what the model systems have taught us so far.J Genet2018
28921554DJ-1 deficiency impairs autophagy and reduces alpha-synuclein phagocytosis by microglia.J Neurochem2017
28461502MEF2D haploinsufficiency downregulates the NRF2 pathway and renders photoreceptors susceptible to light-induced oxidative stress.Proc Natl Acad Sci U S A2017
28738418Molecular Pathway to Protection From Age-Dependent Photoreceptor Degeneration in Mef2 Deficiency.Invest Ophthalmol Vis Sci2017
27544484Astrocytes from old Alzheimer's disease mice are impaired in Aβ uptake and in neuroprotection.Neurobiol Dis2016
24994540Low-level laser therapy ameliorates disease progression in a mouse model of Alzheimer's disease.J Mol Neurosci2015
25894287New insights on Parkinson's disease genes: the link between mitochondria impairment and neuroinflammation.J Neural Transm (Vienna)2015
24355073DJ-1 deficiency triggers microglia sensitivity to dopamine toward a pro-inflammatory phenotype that is attenuated by rasagiline.J Neurochem2014
23313057Preconditioning to mild oxidative stress mediates astroglial neuroprotection in an IL-10-dependent manner.Brain Behav Immun2013
22449754Naphthoquinone-tyrptophan reduces neurotoxic Aβ*56 levels and improves cognition in Alzheimer's disease animal model.Neurobiol Dis2012
22706200Phenylalanine assembly into toxic fibrils suggests amyloid etiology in phenylketonuria.Nat Chem Biol2012
21280087γ-Secretase component presenilin is important for microglia β-amyloid clearance.Ann Neurol2011
20706642Toll-like receptors expression and signaling in glia cells in neuro-amyloidogenic diseases: towards future therapeutic application.Mediators Inflamm2010
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Collaborators

Stuart A Lipton
The Scripps Research Institute, University of California
Co-authored papers 13
Swagata Ghatak
National Institute of Science Education and Research
Co-authored papers 7
Maria Talantova
The Scripps Research Institute
Co-authored papers 5
Rajesh Ambasudhan
The Scripps Research Institute
Co-authored papers 4
Nima Dolatabadi
The Scripps Research Institute
Co-authored papers 4
Tomohiro Nakamura
The Scripps Research Institute
Co-authored papers 4
John R Yates
TheScripps Research Institute
Co-authored papers 3
Ian A Wilson
The Scripps Research Institute, USA The Skaggs Institute for Chemical Biology
Co-authored papers 2
Michael Karin
Co-authored papers 2
Amanda J Roberts
The Scripps Research Institute
Co-authored papers 2
Abdullah Sultan
King Abdulaziz University
Co-authored papers 2
Malina A Bakowski
a division of The Scripps Research Institute La Jolla
Co-authored papers 2
Rommie E Amaro
University of California
Co-authored papers 2
Richard Gao
University of Tubingen
Co-authored papers 1
German R Aleman Muench
Co-authored papers 1
Yin Wu
The Scripps Research Institute
Co-authored papers 1
Nicholas J Schork
University of California San Diego
Co-authored papers 1
Yona Levites
Emory University School of Medicine
Co-authored papers 1
Todd E Golde
Emory Center for Neurodegenerative Disease
Co-authored papers 1
Eliezer Masliah
National Institute On Aging
Co-authored papers 1
Zhenyu Zhong
Co-authored papers 1
Bradley Voytek
Alfred P. Sloan Foundation, National Academy of Sciences, University of California Berkeley, University of California San Diego, University of California, San Diego
Co-authored papers 1
Xuemei Han
Co-authored papers 1
Henry Scott
The Scripps Research Institute
Co-authored papers 1
Release 1.2