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Author Details

Bruce A Hay
University Hospital Wishaw
1984
92
49
PMIDPaper TitleJournal TitlePublished Year
36777072The Perils of Riding Motocross: A Summary of this Extensive, Prospective Study.Indian J Orthop2023
35332133Clueless/CLUH regulates mitochondrial fission by promoting recruitment of Drp1 to mitochondria.Nat Commun2022
36518666Pharmacokinetics of fluorobenzyl polyethylene glycol conjugated tetraiodothyroacetic acid (NP751), a novel anticancer thyrointegrin α<sub>v</sub>β<sub>3</sub> antagonist.Front Pharmacol2022
36879662Discovery of novel thyrointegrin αvβ3 antagonist fb-PMT (NP751) in the management of human glioblastoma multiforme.Neurooncol Adv2022
36512501Gene drive-mediated population elimination for biodiversity conservation. When you come to a fork in the road, take it.Proc Natl Acad Sci U S A2022
33035437Engineering the Composition and Fate of Wild Populations with Gene Drive.Annu Rev Entomol2021
33600432Split versions of Cleave and Rescue selfish genetic elements for measured self limiting gene drive.PLoS Genet2021
33886292New Thyrointegrin α<sub>v</sub>β<sub>3</sub> Antagonist with a Scalable Synthesis, Brain Penetration, and Potent Activity against Glioblastoma Multiforme.J Med Chem2021
34845012Gene drive that results in addiction to a temperature-sensitive version of an essential gene triggers population collapse in <i>Drosophila</i>.Proc Natl Acad Sci U S A2021
32355156A drug-inducible sex-separation technique for insects.Nat Commun2020
33659294Generation, Analyzing and <i>in-vivo</i> Drug Treatment of <i>Drosophila</i> Models with IBMPFD.Bio Protoc2020
32245808Gene drive and resilience through renewal with next generation <i>Cleave and Rescue</i> selfish genetic elements.Proc Natl Acad Sci U S A2020
30760597Cleave and Rescue, a novel selfish genetic element and general strategy for gene drive.Proc Natl Acad Sci U S A2019
29169734Vectored gene delivery for lifetime animal contraception: Overview and hurdles to implementation.Theriogenology2018
30224454Behavior of homing endonuclease gene drives targeting genes required for viability or female fertility with multiplexed guide RNAs.Proc Natl Acad Sci U S A2018
29608276Engineered Reciprocal Chromosome Translocations Drive High Threshold, Reversible Population Replacement in Drosophila.ACS Synth Biol2018
28787415Rules of the road for insect gene drive research and testing.Nat Biotechnol2017
28322724Valosin-containing protein (VCP/p97) inhibitors relieve Mitofusin-dependent mitochondrial defects due to VCP disease mutants.Elife2017
28740759A positive readout single transcript reporter for site-specific mRNA cleavage.PeerJ2017
27841259Selective removal of deletion-bearing mitochondrial DNA in heteroplasmic Drosophila.Nat Commun2016
27702788Mapping a multiplexed zoo of mRNA expression.Development2016
25488845Radiosynthesis and ex vivo evaluation of [(18)F]-(S)-3-(6-(3-fluoropropoxy)benzo[d]isoxazol-3-yl)-5-(methoxymethyl)oxazolidin-2-one for imaging MAO-B with PET.Bioorg Med Chem Lett2015
26439332Vectored antibody gene delivery mediates long-term contraception.Curr Biol2015
26464360Identification of Genes Uniquely Expressed in the Germ-Line Tissues of the Jewel Wasp Nasonia vitripennis.G3 (Bethesda)2015
23654248Novel synthetic Medea selfish genetic elements drive population replacement in Drosophila; a theoretical exploration of Medea-dependent population suppression.ACS Synth Biol2014
27582935Olecranon bursitis: a systematic overview.Shoulder Elbow2014
25054803Medusa: a novel gene drive system for confined suppression of insect populations.PLoS One2014
24492376Identification of germline transcriptional regulatory elements in Aedes aegypti.Sci Rep2014
23541732A synthetic gene drive system for local, reversible modification and suppression of insect populations.Curr Biol2013
23833213The developmental transcriptome of the mosquito Aedes aegypti, an invasive species and major arbovirus vector.G3 (Bethesda)2013
23893741Transcriptome profiling of Nasonia vitripennis testis reveals novel transcripts expressed from the selfish B chromosome, paternal sex ratio.G3 (Bethesda)2013
23519152Essential role of grim-led programmed cell death for the establishment of corazonin-producing peptidergic nervous system during embryogenesis and metamorphosis in Drosophila melanogaster.Biol Open2013
22094363Confinement of gene drive systems to local populations: a comparative analysis.J Theor Biol2012
22759292General principles of single-construct chromosomal gene drive.Evolution2012
22482450Molecular insights into Parkinson's disease.Prog Mol Biol Transl Sci2012
21120926Drosophila caspases involved in developmentally regulated programmed cell death of peptidergic neurons during early metamorphosis.J Comp Neurol2011
21493596Inverse Medea as a novel gene drive system for local population replacement: a theoretical analysis.J Hered2011
21078687Semele: a killer-male, rescue-female system for suppression and replacement of insect disease vector populations.Genetics2011
21062278Medea selfish genetic elements as tools for altering traits of wild populations: a theoretical analysis.Evolution2011
20346676Inactivation of both Foxo and reaper promotes long-term adult neurogenesis in Drosophila.Curr Biol2010
20570677Engineering the genomes of wild insect populations: challenges, and opportunities provided by synthetic Medea selfish genetic elements.J Insect Physiol2010
19217892The deubiquitinase emperor's thumb is a regulator of apoptosis in Drosophila.Dev Biol2009
18275947Differential requirements for the Pax6(5a) genes eyegone and twin of eyegone during eye development in Drosophila.Dev Biol2008
18577702Pharmacologic inhibition of site 1 protease activity inhibits sterol regulatory element-binding protein processing and reduces lipogenic enzyme gene expression and lipid synthesis in cultured cells and experimental animals.J Pharmacol Exp Ther2008
18519643Identification of novel genes involved in light-dependent CRY degradation through a genome-wide RNAi screen.Genes Dev2008
17068333The Drosophila inhibitor of apoptosis (IAP) DIAP2 is dispensable for cell survival, required for the innate immune response to gram-negative bacterial infection, and can be negatively regulated by the reaper/hid/grim family of IAP-binding apoptosis inducers.J Biol Chem2007
18213359Stage-specific differences in the requirements for germline stem cell maintenance in the Drosophila ovary.Cell Stem Cell2007
17583500Aminopyrrolidineamide inhibitors of site-1 protease.Bioorg Med Chem Lett2007
17612403echinus, required for interommatidial cell sorting and cell death in the Drosophila pupal retina, encodes a protein with homology to ubiquitin-specific proteases.BMC Dev Biol2007
17395794A synthetic maternal-effect selfish genetic element drives population replacement in Drosophila.Science2007
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Collaborators

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Co-authored papers 12
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Co-authored papers 11
School of Public Health, UC Berkeley
Co-authored papers 8
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The University of Florida
Co-authored papers 4
Weill Institute for Neurosciences, University of California San Francisco
Co-authored papers 3
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University of California berkeley
Co-authored papers 2
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University of California San Diego
Co-authored papers 2
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University of California San Diego
Co-authored papers 1
J. Craig Venter Institute
Co-authored papers 1
National Institutes of Allergy and Infectious Diseases
Co-authored papers 1
University of Cambridge
Co-authored papers 1
Howard Hughes Medical Institute
Co-authored papers 1
Monash University at Cabrini Health
Co-authored papers 1
Massachusetts Institute of Technology
Co-authored papers 1
Co-authored papers 1
California Institute of Technology
Co-authored papers 1
National Center for Genome Resources
Co-authored papers 1
Lawrence Berkeley National Laboratory
Co-authored papers 1
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University of British Columbia
Co-authored papers 1
University of California
Co-authored papers 1
Northumberland Tyne and Wear NHS Foundation Trust, St Nicholas Hospital
Co-authored papers 1
Global Health Institute, Ecole Polytechnique Federale de Lausanne (EPFL)
Co-authored papers 1
The University of Adelaide Faculty of Health and Medical Sciences
Co-authored papers 1