Author details

Full Name

Peter K Vogt

Affiliation

ORCID

Career Start Year

1958

Papers

348

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36849510	The MYC-regulated lncRNA LNROP (ENSG00000254887) enables MYC-driven cell proliferation by controlling the expression of OCT2.		2023
37394020	Structural and mechanistic insights provided by single particle cryo-EM analysis of phosphoinositide 3-kinase (PI3KÎ±).		2023
36343266	Cryo-EM structures of cancer-specific helical and kinase domain mutations of PI3KÎ±.	Proceedings of the National Academy of Sciences of the United States of America	2022
36095215	Nanobodies and chemical cross-links advance the structural and functional analysis of PI3KÎ±.	Proc Natl Acad Sci U S A	2022
34725156	Cryo-EM structures of PI3KÎ± reveal conformational changes during inhibition and activation.	Proceedings of the National Academy of Sciences of the United States of America	2021
34130216	Synthetic fluorescent MYC probe: Inhibitor binding site elucidation and development of a high-throughput screening assay.	Bioorg Med Chem	2021
33833446	Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications.	Nature Chemistry	2021
33240760	A Single-Stranded DNA-Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks.	Advanced Science	2020
32156728	An MXD1-derived repressor peptide identifies noncoding mediators of MYC-driven cell proliferation.	Proceedings of the National Academy of Sciences of the United States of America	2020
30669277	The Importance of Being Non-Defective: A Mini Review Dedicated to the Memory of Jan Svoboda.	Viruses	2019
31567064	From Viruses to Genes to Cells.	Annual Review of Virology	2019
31652979	Cooperates with to Promote MYC Activity and Tumorigenesis via the Bromodomain Protein BRD9.	Cancers	2019
30037753	Synthetic molecules for disruption of the MYC protein-protein interface.	Bioorganic and Medicinal Chemistry	2018
30205700	Isoform-specific activities of the regulatory subunits of phosphatidylinositol 3-kinases - potentially novel therapeutic targets.	Expert Opinion on Therapeutic Targets	2018
28696308	tsRNA signatures in cancer.	Proc Natl Acad Sci U S A	2017
28915558	Domain analysis reveals striking functional differences between the regulatory subunits of phosphatidylinositol 3-kinase (PI3K), p85Î± and p85Î².	Oncotarget	2017
27104980	A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling.	Cell	2016
26811502	MINCR is not a MYC-induced lncRNA.	Proceedings of the National Academy of Sciences of the United States of America	2016
26196237	ProteinInferencer: Confident protein identification and multiple experiment comparison for large scale proteomics projects.	J Proteomics	2015
25583473	The butterfly effect in cancer: a single base mutation can remodel the cell.	Proc Natl Acad Sci U S A	2015
27308543	A butterfly effect in cancer.	Mol Cell Oncol	2015
26186937	A brave new MYC-amplified world.	Aging	2015
26182239	Quantification of nascent transcription by bromouridine immunocapture nuclear run-on RT-qPCR.		2015
26156430	MYCNOS functions as an antisense RNA regulating MYCN.	RNA Biology	2015
24735923	MicroRNA-135b promotes cancer progression by acting as a downstream effector of oncogenic pathways in colon cancer.	Cancer Cell	2014
25587025	MYC regulates the non-coding transcriptome.	Oncotarget	2014
25326649	In vivo quantification and perturbation of Myc-Max interactions and the impact on oncogenic potential.	Oncotarget	2014
25385636	Oncogenic activity of the regulatory subunit p85Î² of phosphatidylinositol 3-kinase (PI3K).	Proceedings of the National Academy of Sciences of the United States of America	2014
26390751	RICHARD BING: 12 OCTOBER 1909 - 8 NOVEMBER 2010.	Proceedings of the American Philosophical Society	2014
25114221	Inhibitor of MYC identified in a KrÃ¶hnke pyridine library.	Proceedings of the National Academy of Sciences of the United States of America	2014
23839098	An Algorithm for Generating Small RNAs Capable of Epigenetically Modulating Transcriptional Gene Silencing and Activation in Human Cells.	Molecular Therapy - Nucleic Acids	2013
22898541	Retroviral oncogenes: a historical primer.	Nature Reviews Cancer	2012
22627671	Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence.	Cell Cycle	2012
22331869	Progress in breast cancer research.	Proc Natl Acad Sci U S A	2012
22110182	100 years of Rous sarcoma virus.	Journal of Experimental Medicine	2011
22348200	PI3K and STAT3: a new alliance.	Cancer Discovery	2011
21350335	Protein expression profiles of C3H 10T1/2 murine fibroblasts and of isogenic cells transformed by the H1047R mutant of phosphoinositide 3-kinase (PI3K).	Cell Cycle	2011
21362546	PI3K p110Î²: more tightly controlled or constitutively active?	Molecular Cell	2011
21311223	Understanding PLZF: two transcriptional targets, REDD1 and smooth muscle Î±-actin, define new questions in growth control, senescence, self-renewal and tumor suppression.	Cell Cycle	2011
22045127	Addition of N-terminal peptide sequences activates the oncogenic and signaling potentials of the catalytic subunit p110Î± of phosphoinositide-3-kinase.	Cell Cycle	2011
21670491	Phosphorylation of AKT: a mutational analysis.	Oncotarget	2011
21750219	PF-04691502, a potent and selective oral inhibitor of PI3K and mTOR kinases with antitumor activity.	Molecular Cancer Therapeutics	2011
21609016	Design, synthesis, and validation of a Î²-turn mimetic library targeting protein-protein and peptide-receptor interactions.	J Am Chem Soc	2011
21788516	Essential role of Stat3 in PI3K-induced oncogenic transformation.	Proc Natl Acad Sci U S A	2011
21779424	Oncogenes and the revolution in cancer research: homage to hidesaburo hanafusa (1929-2009).	Genes and Cancer	2010
21166102	Cell entry by non-enveloped viruses.	Current Topics in Microbiology and Immunology	2010
20713702	Cancer-derived mutations in the regulatory subunit p85alpha of phosphoinositide 3-kinase function through the catalytic subunit p110alpha.	Proceedings of the National Academy of Sciences of the United States of America	2010
21132100	Therapeutic Targeting of Myc.	Genes and Cancer	2010
20009532	Hot-spot mutations in p110alpha of phosphatidylinositol 3-kinase (pI3K): differential interactions with the regulatory subunit p85 and with RAS.	Cell Cycle	2010
20549473	PI3K: from the bench to the clinic and back.	Current Topics in Microbiology and Immunology	2010