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Author Details
Full Name
Aoife McLysaght
Affiliation
Smurfit Institute of Genetics, Trinity College Dublin
ORCID
Career Start Year
2000
Papers
56
H Index
28
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36765060
Reply to: Available data do not rule out Ctenophora as the sister group to all other Metazoa.
Nat Commun
2023
37579156
Horizontal transfer of vertebrate vision gene <i>IRBP</i> into the chordate ancestor.
Proc Natl Acad Sci U S A
2023
37776514
Ohnologs and SSD Paralogs Differ in Genomic and Expression Features Related to Dosage Constraints.
Genome Biol Evol
2023
37208359
Independent rediploidization masks shared whole genome duplication in the sturgeon-paddlefish ancestor.
Nat Commun
2023
35018456
Evidence from Drosophila Supports Higher Duplicability of Faster Evolving Genes.
Genome Biol Evol
2022
35852990
The deceptive simplicity of mendelian genetics.
PLoS Biol
2022
36543139
De novo birth of functional microproteins in the human lineage.
Cell Rep
2022
36333285
Author Correction: Evidence for sponges as sister to all other animals from partitioned phylogenomics with mixture models and recoding.
Nat Commun
2022
35932283
Micro(RNA)-cloud can perpetuate physiological adaptation of skeletal muscle to exercise and energy imbalance.
J Physiol
2022
33398071
Author Correction: De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences.
Nat Commun
2021
33741994
Evidence for sponges as sister to all other animals from partitioned phylogenomics with mixture models and recoding.
Nat Commun
2021
34326346
Publisher Correction: Reconstruction of proto-vertebrate, protocyclostome and proto-gnathostome genomes provides new insights into early vertebrate evolution.
Nat Commun
2021
34301952
Reconstruction of proto-vertebrate, proto-cyclostome and proto-gnathostome genomes provides new insights into early vertebrate evolution.
Nat Commun
2021
32034123
De novo emergence of adaptive membrane proteins from thymine-rich genomic sequences.
Nat Commun
2020
32066524
Synteny-based analyses indicate that sequence divergence is not the main source of orphan genes.
Elife
2020
30298392
Computational Prediction of De Novo Emerged Protein-Coding Genes.
Methods Mol Biol
2019
30963617
Evolutionary journey and characterisation of a novel pan-gene associated with beer strains of Saccharomyces cerevisiae.
Yeast
2019
30674659
Macrosynteny analysis shows the absence of ancient whole-genome duplication in lepidopteran insects.
Proc Natl Acad Sci U S A
2019
29126243
Faster Evolving Primate Genes Are More Likely to Duplicate.
Mol Biol Evol
2018
30252115
Pseudogenes Provide Evolutionary Evidence for the Competitive Endogenous RNA Hypothesis.
Mol Biol Evol
2018
29628311
A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities.
Mol Cell
2018
28863777
Dosage-sensitive genes in evolution and disease.
BMC Biol
2017
28176757
Dosage sensitivity is a major determinant of human copy number variant pathogenicity.
Nat Commun
2017
28881993
Genomes as documents of evolutionary history: a probabilistic macrosynteny model for the reconstruction of ancestral genomes.
Bioinformatics
2017
27056411
De Novo Genes Arise at a Slow but Steady Rate along the Primate Lineage and Have Been Subject to Incomplete Lineage Sorting.
Genome Biol Evol
2016
27452112
Open questions in the study of de novo genes: what, how and why.
Nat Rev Genet
2016
27297469
Spatial Colocalization of Human Ohnolog Pairs Acts to Maintain Dosage-Balance.
Mol Biol Evol
2016
26494712
A chromatin-independent role of Polycomb-like 1 to stabilize p53 and promote cellular quiescence.
Genes Dev
2015
26323763
New genes from non-coding sequence: the role of de novo protein-coding genes in eukaryotic evolutionary innovation.
Philos Trans R Soc Lond B Biol Sci
2015
24368850
Ohnologs are overrepresented in pathogenic copy number mutations.
Proc Natl Acad Sci U S A
2014
23268114
A survey of host range genes in poxvirus genomes.
Infect Genet Evol
2013
23917329
Genome-wide deserts for copy number variation in vertebrates.
Nat Commun
2013
23572418
Treasurer's report for financial year (FY) 2011.
Genome Biol Evol
2013
23584977
Treasurer's report for financial year (FY) 2011.
Mol Biol Evol
2013
22392987
Mammalian X chromosome inactivation evolved as a dosage-compensation mechanism for dosage-sensitive genes on the X chromosome.
Proc Natl Acad Sci U S A
2012
23185269
De novo origin of protein-coding genes in murine rodents.
PLoS One
2012
22835904
Positionally biased gene loss after whole genome duplication: evidence from human, yeast, and plant.
Genome Res
2012
22490996
Evolution of vertebrate tissues driven by differential modes of gene duplication.
DNA Res
2012
21881679
Patterns of indirect protein interactions suggest a spatial organization to metabolism.
Mol Biosyst
2011
22102832
De novo origins of human genes.
PLoS Genet
2011
20439718
Ohnologs in the human genome are dosage balanced and frequently associated with disease.
Proc Natl Acad Sci U S A
2010
20509897
Duplicability of self-interacting human genes.
BMC Evol Biol
2010
19285746
The complex relationship of gene duplication and essentiality.
Trends Genet
2009
19726446
Recent de novo origin of human protein-coding genes.
Genome Res
2009
18304319
Identification of multiple independent horizontal gene transfers into poxviruses using a comparative genomics approach.
BMC Evol Biol
2008
18774619
Evolutionary steps of sex chromosomes are reflected in retrogenes.
Trends Genet
2008
18573844
Interacting gene clusters and the evolution of the vertebrate immune system.
Mol Biol Evol
2008
16720694
High rate of recent intron gain and loss in simultaneously duplicated Arabidopsis genes.
Mol Biol Evol
2006
15585524
Porter: a new, accurate server for protein secondary structure prediction.
Bioinformatics
2005
15262815
Genomic features in the breakpoint regions between syntenic blocks.
Bioinformatics
2004
1 - 50 of 56
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row(s) 1 - 30 of 30
Collaborators
Nikolaos Vakirlis
Institute for General Microbiology, Christian Albrechts University
Co-authored papers
6
Karsten Hokamp
Smurfit Institute of Genetics, Trinity College of Dublin
Co-authored papers
5
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University of Pittsburgh School of Medicine.
Co-authored papers
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University of Pittsburgh
Co-authored papers
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University of Pittsburgh
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Co-authored papers
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University of California San Diego
Co-authored papers
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University of California San Diego Health Moores Cancer Center.
Co-authored papers
2
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University of Pittsburgh
Co-authored papers
2
Omer Acar
University of Illinois at Chicago
Co-authored papers
2
Eric Conway
Conway Institute, University College Dublin
Co-authored papers
2
Nelson C Coelho
University of Pittsburgh, USA Pittsburgh Center for Evolutionary Biology and Medicine
Co-authored papers
2
Adrian P Bracken
Smurfit Institute of Genetics, Trinity College Dublin
Co-authored papers
2
Chris Clee
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1
Elia Stupka
Center for Omics Sciences, IRCCS San Raffaele Scientific Institute
Co-authored papers
1
Arian F A Smit
Co-authored papers
1
Jean Thierry-Mieg
Co-authored papers
1
Michael L Metzker
Co-authored papers
1
Jill P Mesirov
University of California San Diego
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1
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