Author details

Full Name

George M Shaw

Affiliation

ORCID

Career Start Year

1978

Papers

329

H Index

111

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37502921	Assessing the impact of autologous neutralizing antibodies on viral rebound in postnatally SHIV-infected ART-treated infant rhesus macaques.	bioRxiv	2023
35962033	Strategies for HIV-1 vaccines that induce broadly neutralizing antibodies.	Nature Reviews Immunology	2023
37874153	Host immunity associated with spontaneous suppression of viremia in therapy-naÃ¯ve young rhesus macaques following neonatal SHIV infection.		2023
37553348	Intradermal but not intramuscular modified vaccinia Ankara immunizations protect against intravaginal tier2 simian-human immunodeficiency virus challenges in female macaques.	Nat Commun	2023
37399208	Adaptation of a transmitted/founder simian-human immunodeficiency virus for enhanced replication in rhesus macaques.		2023
37207227	Efficient <i>ex vivo</i> expansion of conserved element vaccine-specific CD8+ T-cells from SHIV-infected, ART-suppressed nonhuman primates.	Front Immunol	2023
36629414	A Germline-Targeting Chimpanzee SIV Envelope Glycoprotein Elicits a New Class of V2-Apex Directed Cross-Neutralizing Antibodies.	mBio	2023
34986348	Potent anti-viral activity of a trispecific HIV neutralizing antibody in SHIV-infected monkeys.	Cell Rep	2022
35907918	Leveraging antigenic seniority for maternal vaccination to prevent mother-to-child transmission of HIV-1.	NPJ Vaccines	2022
35588376	Repeated exposure to heterologous hepatitis C viruses associates with enhanced neutralizing antibody breadth and potency.	J Clin Invest	2022
35387986	Zoonotic origin of the human malaria parasite Plasmodium malariae from African apes.	Nature Communications	2022
35880874	Correction for Rudicell et al., "High Prevalence of Simian Immunodeficiency Virus Infection in a Community of Savanna Chimpanzees".	Journal of Virology	2022
35876514	Correction for Sharp et al., "Simian Immunodeficiency Virus Infection of Chimpanzees".	Journal of Virology	2022
36070369	Stabilized HIV-1 envelope immunization induces neutralizing antibodies to the CD4bs and protects macaques against mucosal infection.	Science Translational Medicine	2022
34699383	Dynamics and origin of rebound viremia in SHIV-infected infant macaques following interruption of long-term ART.	JCI insight	2021
34019795	Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.	Cell	2021
34232070	Enhanced Ability of Plant-Derived PGT121 Glycovariants To Eliminate HIV-1-Infected Cells.	Journal of Virology	2021
33568508	Immune Responses and Viral Persistence in Simian/Human Immunodeficiency Virus SHIV.C.CH848-Infected Rhesus Macaques.	Journal of Virology	2021
33771926	CD4 receptor diversity represents an ancient protection mechanism against primate lentiviruses.	Proc Natl Acad Sci U S A	2021
33658341	New SHIVs and Improved Design Strategy for Modeling HIV-1 Transmission, Immunopathogenesis, Prevention and Cure.	J Virol	2021
34193339	Predictors of Nonseroconversion after SARS-CoV-2 Infection.	Emerg Infect Dis	2021
33556148	The C3/465 glycan hole cluster in BG505 HIV-1 envelope is the major neutralizing target involved in preventing mucosal SHIV infection.	PLoS Pathog	2021
33441429	Heightened resistance to host type 1 interferons characterizes HIV-1 at transmission and after antiretroviral therapy interruption.	Sci Transl Med	2021
34432859	Antibody responses induced by SHIV infection are more focused than those induced by soluble native HIV-1 envelope trimers in non-human primates.	PLoS Pathogens	2021
32667919	Assessing routes of hepatitis C transmission in HIV-infected men who have sex with men using single genome sequencing.	PLoS ONE	2020
32132241	Differential Outcomes following Optimization of Simian-Human Immunodeficiency Viruses from Clades AE, B, and C.	Journal of Virology	2020
32402293	Co-immunization of DNA and Protein in the Same Anatomical Sites Induces Superior Protective Immune Responses against SHIV Challenge.	Cell Reports	2020
32393800	T cell-inducing vaccine durably prevents mucosal SHIV infection even with lower neutralizing antibody titers.	Nat Med	2020
32209678	Estimating the Timing of Early Simian-Human Immunodeficiency Virus Infections: a Comparison between Poisson Fitter and BEAST.	mBio	2020
32817214	SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques.	J Virol	2020
33087463	Simian-Human Immunodeficiency Virus SHIV.C.CH505 Persistence in ART-Suppressed Infant Macaques Is Characterized by Elevated SHIV RNA in the Gut and a High Abundance of Intact SHIV DNA in Naive CD4<sup>+</sup> T Cells.	J Virol	2020
31513771	A Meta-analysis of Passive Immunization Studies Shows that Serum-Neutralizing Antibody Titer Associates with Protection against SHIV Challenge.		2019
31748275	Contribution of proteasome-catalyzed peptide -splicing to viral targeting by CD8 T cells in HIV-1 infection.	Proceedings of the National Academy of Sciences of the United States of America	2019
30552025	Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers.	Immunity	2019
30593623	Molecular Identification of Transmitted/Founder Hepatitis C Viruses and Their Progeny by Single Genome Sequencing.	Methods in Molecular Biology	2019
31092583	Simian-Human Immunodeficiency Virus SHIV.CH505-Infected Infant and Adult Rhesus Macaques Exhibit Similar Env-Specific Antibody Kinetics, despite Distinct T-Follicular Helper and Germinal Center B Cell Landscapes.	J Virol	2019
31488511	Analytical Treatment Interruption after Short-Term Antiretroviral Therapy in a Postnatally Simian-Human Immunodeficiency Virus-Infected Infant Rhesus Macaque Model.	mBio	2019
31217249	Simian-Human Immunodeficiency Virus SHIV.CH505 Infection of Rhesus Macaques Results in Persistent Viral Replication and Induces Intestinal Immunopathology.	Journal of Virology	2019
31112523	High multiplicity infection following transplantation of hepatitis C virus-positive organs.	Journal of Clinical Investigation	2019
30943274	Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes.	PLoS Pathog	2019
30718403	CD4 receptor diversity in chimpanzees protects against SIV infection.	Proc Natl Acad Sci U S A	2019
29765018	Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection.	Nat Commun	2018
30355496	Completeness of HIV-1 Envelope Glycan Shield at Transmission Determines Neutralization Breadth.	Cell Reports	2018
30439341	Broadly Neutralizing Antibody Mediated Clearance of Human Hepatitis C Virus Infection.	Cell Host Microbe	2018
29987026	Superinfection and cure of infected cells as mechanisms for hepatitis C virus adaptation and persistence.	Proceedings of the National Academy of Sciences of the United States of America	2018
28100618	Influence of the Envelope gp120 Phe 43 Cavity on HIV-1 Sensitivity to Antibody-Dependent Cell-Mediated Cytotoxicity Responses.	Journal of Virology	2017
28469084	Broadly neutralizing antibodies with few somatic mutations and hepatitis C virus clearance.	JCI Insight	2017
28910384	Correction: Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection.	PLoS Pathogens	2017
28759651	Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection.	PLoS Pathogens	2017
28576126	Effective treatment of SIVcpz-induced immunodeficiency in a captive western chimpanzee.	Retrovirology	2017