Author details

Full Name

Reda Rawi

Affiliation

ORCID

Career Start Year

2010

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37098956	Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.		2023
36382536	Antibodies as drugs-a Keystone Symposia report.	Annals of the New York Academy of Sciences	2023
37766115	Enhancing Anti-SARS-CoV-2 Neutralizing Immunity by Genetic Delivery of Enveloped Virus-like Particles Displaying SARS-CoV-2 Spikes.	Vaccines (Basel)	2023
37989731	Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site.		2023
37345226	Improved pharmacokinetics of HIV-neutralizing VRC01-class antibodies achieved by reduction of net positive charge on variable domain.		2023
37436900	Improved HIV-1 neutralization breadth and potency of V2-apex antibodies by in silico design.		2023
37436899	HIV-1 neutralizing antibodies elicited in humans by a prefusion-stabilized envelope trimer form a reproducible class targeting fusion peptide.	Cell Rep	2023
37295404	Vaccine elicitation and structural basis for antibody protection against alphaviruses.	Cell	2023
36729903	Bispecific antibody CAP256.J3LS targets V2-apex and CD4-binding sites with high breadth and potency.	MAbs	2023
35115707	A single residue in influenza virus H2 hemagglutinin enhances the breadth of the B cell response elicited by H2 vaccination.	Nature Medicine	2022
35841885	Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability.	Structure	2022
36356572	Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses.	Immunity	2022
36344847	Cryo-EM structures of prefusion SIV envelope trimer.	Nat Struct Mol Biol	2022
35489332	Structure of an influenza group 2-neutralizing antibody targeting the hemagglutinin stem supersite.	Structure	2022
35736810	Highly protective antimalarial antibodies via precision library generation and yeast display screening.	Journal of Experimental Medicine	2022
35413243	Structural basis for llama nanobody recognition and neutralization of HIV-1 at the CD4-binding site.	Structure	2022
35537058	-Symmetric Aromatic Core of Griffithsin Is Essential for Potent Anti-HIV Activity.	ACS Chemical Biology	2022
35319830	Development of Neutralization Breadth against Diverse HIV-1 by Increasing Ab-Ag Interface on V2.	Advanced Science	2022
34864901	GLYCO: a tool to quantify glycan shielding of glycosylated proteins.		2022
34753907	Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces.	Nat Commun	2021
34200826	Structures of HIV-1 Neutralizing Antibody 10E8 Delineate the Mechanistic Basis of Its Multi-Peak Behavior on Size-Exclusion Chromatography.	Antibodies (Basel)	2021
34135892	Sequence-Signature Optimization Enables Improved Identification of Human HV6-1-Derived Class Antibodies That Neutralize Diverse Influenza A Viruses.	Front Immunol	2021
33649208	Mutational fitness landscapes reveal genetic and structural improvement pathways for a vaccine-elicited HIV-1 broadly neutralizing antibody.	Proc Natl Acad Sci U S A	2021
34408080	Blocking Î±Î² integrin delays viral rebound in SHIV-infected macaques treated with anti-HIV broadly neutralizing antibodies.	Science Translational Medicine	2021
34788599	Vaccination in a humanized mouse model elicits highly protective PfCSP-targeting anti-malarial antibodies.	Immunity	2021
34731616	Structural basis of glycan276-dependent recognition by HIV-1 broadly neutralizing antibodies.	Cell Rep	2021
33238130	Automated Design by Structure-Based Stabilization and Consensus Repair to Achieve Prefusion-Closed Envelope Trimers in a Wide Variety of HIV Strains.	Cell Reports	2020
32268107	Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition.	Cell Rep	2020
32130953	VRC34-Antibody Lineage Development Reveals How a Required Rare Mutation Shapes the Maturation of a Broad HIV-Neutralizing Lineage.	Cell Host Microbe	2020
32295908	Development of a 3Mut-Apex-Stabilized Envelope Trimer That Expands HIV-1 Neutralization Breadth When Used To Boost Fusion Peptide-Directed Vaccine-Elicited Responses.	Journal of Virology	2020
31603511	BCrystal: an interpretable sequence-based protein crystallization predictor.		2020
33205023	Glycan Positioning Impacts HIV-1 Env Glycan-Shield Density, Function, and Recognition by Antibodies.	iScience	2020
32877670	Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodies Reveal the Mechanism for Its Recurrent Elicitation.	Cell Rep	2020
30995238	Consistent elicitation of cross-clade HIV-neutralizing responses achieved in guinea pigs after fusion peptide priming by repetitive envelope trimer boosting.	PLoS One	2019
30590437	KinVis: a visualization tool to detect cryptic relatedness in genetic datasets.		2019
30192921	Prediction of protein group function by iterative classification on functional relevance network.	Bioinformatics	2019
30471922	Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition.	Structure	2019
30876875	Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual.	Immunity	2019
30760721	Improvement of antibody functionality by structure-guided paratope engraftment.	Nature Communications	2019
31348886	Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.	Cell	2019
29069295	PaRSnIP: sequence-based protein solubility prediction using gradient boosting machine.		2018
30355496	Completeness of HIV-1 Envelope Glycan Shield at Transmission Determines Neutralization Breadth.	Cell Reports	2018
29975771	Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV.	PLoS Pathog	2018
29867235	Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1.	Nat Med	2018
30290119	CRISPro: An Automated Pipeline for Protein Conformation Stabilization by Proline.	Journal of Chemical Information and Modeling	2018
30322395	Correction to: Harnessing Qatar Biobank to understand type 2 diabetes andÂ obesity inÂ adult Qataris fromÂ theÂ First Qatar Biobank Project.	Journal of Translational Medicine	2018
29444432	Surface-Matrix Screening Identifies Semi-specific Interactions that Improve Potency of a Near Pan-reactive HIV-1-Neutralizing Antibody.	Cell Rep	2018
29554211	DeepSol: a deep learning framework for sequence-based protein solubility prediction.		2018
29650030	Harnessing Qatar Biobank to understand type 2 diabetes and obesity in adult Qataris from the First Qatar Biobank Project.	Journal of Translational Medicine	2018
29548671	A Neutralizing Antibody Recognizing Primarily N-Linked Glycan Targets the Silent Face of the HIV Envelope.	Immunity	2018