Author details

Full Name

Schahram Akbarian

Affiliation

ORCID

Career Start Year

1988

Papers

203

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
38086109	The schizophrenia syndrome, circa 2024: What we know and how that informs its nature.	Schizophr Res	2024
34493831	Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk.	Mol Psychiatry	2023
36357715	RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation.	Acta Neuropathologica	2023
37947981	Genomic Exploration of the Brain in People Infected with HIV-Recent Progress and the Road Ahead.		2023
37676934	Chromosomal contacts change with age.		2023
37598835	Mir125b-1 is Not Imprinted in Human Brain and Shows Developmental Expression Changes in Mouse Brain.		2023
38032195	HIV-1 infection of genetically engineered iPSC-derived central nervous system-engrafted microglia in a humanized mouse model.		2023
37985666	Genomic data resources of the Brain Somatic Mosaicism Network for neuropsychiatric diseases.	Sci Data	2023
37699936	Single nucleus transcriptomics of ventral midbrain identifies glial activation associated with chronic opioid use disorder.		2023
36945611	Single Nucleus Transcriptomics Reveals Pervasive Glial Activation in Opioid Overdose Cases.		2023
36918719	Mir125b-2 imprinted in human but not mouse brain regulates hippocampal function and circuit in mice.		2023
37503149	R-loop landscapes in the developing human brain are linked to neural differentiation and cell-type specific transcription.		2023
37502907	Schizophrenia Risk Mapping and Functional Engineering of the 3D Genome in Three Neuronal Subtypes.		2023
35325615	PPARdelta activation induces metabolic and contractile maturation of human pluripotent stem cell-derived cardiomyocytes.	Cell Stem Cell	2022
36360237	3D Genome Plasticity in Normal and Diseased Neurodevelopment.	Genes	2022
35449295	Cylindromatosis drives synapse pruning and weakening by promoting macroautophagy through Akt-mTOR signaling.	Molecular Psychiatry	2022
35505091	The tRNA regulome in neurodevelopmental and neuropsychiatric disease.	Molecular Psychiatry	2022
35567414	RTL1/PEG11 imprinted in human and mouse brain mediates anxiety-like and social behaviors and regulates neuronal excitability in the locus coeruleus.	Human Molecular Genetics	2022
36274170	High-resolution transcriptomics informs glial pathology in human temporal lobe epilepsy.	Acta Neuropathol Commun	2022
35422469	Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits.	Molecular Psychiatry	2022
36064543	A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility.	NPJ Genom Med	2022
35794187	Correction: Chromatin architecture in addiction circuitry identifies risk genes and potential biological mechanisms underlying cigarette smoking and alcohol use traits.	Molecular Psychiatry	2022
36443832	Correction: High-resolution transcriptomics informs glial pathology in human temporal lobe epilepsy.	Acta Neuropathol Commun	2022
36525955	HIV integration in the human brain is linked to microglial activation and 3D genome remodeling.		2022
34991947	Towards DSM 10: A bio-classification of developmental schizophrenia?	Schizophrenia Research	2022
35301427	Convergence of case-specific epigenetic alterations identify a confluence of genetic vulnerabilities tied to opioid overdose.	Mol Psychiatry	2022
35332326	Chromatin domain alterations linked to 3D genome organization in a large cohort of schizophrenia and bipolar disorder brains.	Nat Neurosci	2022
35296809	Targeting histone demethylase LSD1 for treatment of deficits in autism mouse models.	Molecular Psychiatry	2022
34880236	Author Correction: Neuronal Nsun2 deficiency produces tRNA epitranscriptomic alterations and proteomic shifts impacting synaptic signaling and behavior.	Nature Communications	2021
33636110	Common Genetic Variation in Humans Impacts In Vitro Susceptibility to SARS-CoV-2 Infection.	Stem Cell Reports	2021
34281603	Single-nucleus transcriptome analysis of human brain immune response in patients with severe COVID-19.	Genome Med	2021
34054438	An Adolescent Sensitive Period for Social Dominance Hierarchy Plasticity Is Regulated by Cortical Plasticity Modulators in Mice.	Frontiers in Neural Circuits	2021
34100031	IL10RB as a key regulator of COVID-19 host susceptibility and severity.	medRxiv	2021
33938880	Isolation of Adult Human Astrocyte Populations from Fresh-frozen Cortex using Fluorescence-Activated Nuclei Sorting.	Journal of Visualized Experiments	2021
34025350	Environmental Enrichment Induces Epigenomic and Genome Organization Changes Relevant for Cognition.	Front Mol Neurosci	2021
33131715	Parsing the Functional Impact of Noncoding Genetic Variants in the Brain Epigenome.	Biological Psychiatry	2021
34389722	Neuronal Nsun2 deficiency produces tRNA epitranscriptomic alterations and proteomic shifts impacting synaptic signaling and behavior.	Nature Communications	2021
34903713	Neuron-specific chromosomal megadomain organization is adaptive to recent retrotransposon expansions.	Nat Commun	2021
34883504	Publicly Available hiPSC Lines with Extreme Polygenic Risk Scores for Modeling Schizophrenia.	Complex Psychiatry	2021
31277978	CRISPR-based functional evaluation of schizophrenia risk variants.	Schizophrenia Research	2020
32081848	Prefrontal parvalbumin interneurons require juvenile social experience to establish adult social behavior.	Nature Communications	2020
32075678	A chromosomal connectome for psychiatric and metabolic risk variants in adult dopaminergic neurons.	Genome Med	2020
31813801	Special volume: The genomics and epigenomics of schizophrenia.	Schizophrenia Research	2020
32152537	A computational tool (H-MAGMA) for improved prediction of brain-disorder risk genes by incorporating brain chromatin interaction profiles.	Nature Neuroscience	2020
32710489	Genotype-phenotype correlation at codon 1740 of SETD2.	Am J Med Genet A	2020
32868932	A prefrontal-paraventricular thalamus circuit requires juvenile social experience to regulate adult sociability in mice.	Nature Neuroscience	2020
32578147	Investigation of Schizophrenia with Human Induced Pluripotent Stem Cells.	Advances in neurobiology	2020
32674842	Epigenetic Clocks in Schizophrenia: Promising Biomarkers, Foggy Clockwork.	Biological Psychiatry	2020
32995783	Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection.	bioRxiv	2020
30089790	Lipidome alterations in human prefrontal cortex during development, aging, and cognitive disorders.	Molecular Psychiatry	2020