Author details

Full Name

James P Pirruccello

Affiliation

ORCID

Career Start Year

2010

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37694688	Genetically predicted gestational age and birth weight are associated with cardiac and pulmonary vascular remodelling in adulthood.	Eur J Prev Cardiol	2024
37992628	Sex differences in ascending aortic size reporting and growth on chest computed tomography and magnetic resonance imaging.		2024
38095107	Using Genomics to Identify Novel Therapeutic Targets for Aortic Disease.	Arterioscler Thromb Vasc Biol	2024
37502935	The Cardiovascular Impact and Genetics of Pericardial Adiposity.	medRxiv	2023
36131050	Genetics and mechanisms of thoracic aortic disease.	Nat Rev Cardiol	2023
38042913	Selenoprotein deficiency disorder predisposes to aortic aneurysm formation.	Nat Commun	2023
37662232	AORTA Gene: Polygenic prediction improves detection of thoracic aortic aneurysm.	medRxiv	2023
37278238	Genetic Susceptibility to Atrial Fibrillation Identified via Deep Learning of 12-Lead Electrocardiograms.	Circ Genom Precis Med	2023
37205587	Assessment of valvular function in over 47,000 people using deep learning-based flow measurements.	medRxiv	2023
37081215	Genetics of myocardial interstitial fibrosis in the human heart and association with disease.	Nat Genet	2023
36959364	Adjusting for common variant polygenic scores improves yield in rare variant association analyses.	Nat Genet	2023
36580284	Machine Learning to Understand Genetic and Clinical Factors Associated With the Pulse Waveform Dicrotic Notch.	Circ Genom Precis Med	2023
36576811	Predictive Utility of a Coronary Artery Disease Polygenic Risk Score in Primary Prevention.	JAMA Cardiol	2023
37019578	The Genetic Determinants of AorticÂ Distention.	J Am Coll Cardiol	2023
37264683	Association of genetic risk and outcomes in patients with atrial fibrillation: interactions with early rhythm control in the EAST-AFNET4 trial.	Cardiovasc Res	2023
36949957	<i>TP53-</i>mediated clonal hematopoiesis confers increased risk for incident atherosclerotic disease.	Nat Cardiovasc Res	2023
37453748	Machine learning-based markers for CAD.		2023
37126682	A human FLII gene variant alters sarcomeric actin thin filament length and predisposes to cardiomyopathy.		2023
36944631	Clinical and genetic associations of deep learning-derived cardiac magnetic resonance-based left ventricular mass.	Nat Commun	2023
37308786	Genome-wide association study of thoracic aortic aneurysm and dissection in the Million Veteran Program.	Nat Genet	2023
37225367	Increased Risk ofÂ Thoracic Aortic Aneurysms With JAK2Â V617F.	J Am Coll Cardiol	2023
35234813	Fibrillar Collagen Variants in Spontaneous Coronary Artery Dissection.	JAMA Cardiol	2022
36372681	Quantifying the phenome-wide disease burden of obesity using electronic health records and genomics.	Obesity (Silver Spring)	2022
35772917	LMNA Variants and Risk of Adult-Onset Cardiac Disease.	J Am Coll Cardiol	2022
36180445	Publisher Correction: Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes.	Nat Commun	2022
36042188	Endophenotype effect sizes support variant pathogenicity in monogenic disease susceptibility genes.	Nat Commun	2022
36172868	Aortic Cellular Diversity and Quantitative Genome-Wide Association Study Trait Prioritization Through Single-Nuclear RNA Sequencing of the Aneurysmal Human Aorta.	Arterioscler Thromb Vasc Biol	2022
35902171	Spatially Distinct Genetic Determinants of Aortic Dimensions Influence Risks of Aneurysm and Stenosis.	J Am Coll Cardiol	2022
35383479	Genetic Association of Body Mass Index With Pathologic Left Ventricular Remodeling.	J Am Heart Assoc	2022
36056190	Wearable accelerometer-derived physical activity and incident disease.	NPJ Digit Med	2022
35544052	Association of Pathogenic DNA Variants Predisposing to Cardiomyopathy With Cardiovascular Disease Outcomes and All-Cause Mortality.	JAMA Cardiol	2022
36378208	Development of a Prediction Model for Ascending Aortic Diameter Among Asymptomatic Individuals.	JAMA	2022
34698806	Dnmt3a-mutated clonal hematopoiesis promotes osteoporosis.	J Exp Med	2021
34126762	Deep Learning to Predict Cardiac Magnetic Resonance-Derived Left Ventricular Mass and Hypertrophy From 12-Lead ECGs.	Circ Cardiovasc Imaging	2021
34015477	Cardiovascular and KidneyÂ Outcomes Across the GlycemicÂ Spectrum: Insights From the UK Biobank.	Journal of the American College of Cardiology	2021
33846329	Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices.	Nat Commun	2021
34106216	Association of Diet Quality With Prevalence of Clonal Hematopoiesis and Adverse Cardiovascular Events.	JAMA Cardiology	2021
33283203	Elevated Blood Pressure Increases Pneumonia Risk: Epidemiological Association and Mendelian Randomization in the UK Biobank.	Med	2021
33115266	Lp(a) (Lipoprotein[a]) Concentrations and Incident Atherosclerotic Cardiovascular Disease: New Insights From a Large National Biobank.	Arterioscler Thromb Vasc Biol	2021
33161765	Premature Menopause, Clonal Hematopoiesis, and Coronary Artery Disease in Postmenopausal Women.	Circulation	2021
35265898	Deep learning to estimate cardiac magnetic resonance-derived left ventricular mass.	Cardiovasc Digit Health J	2021
34608296	Author Correction: Genetics of 35 blood and urine biomarkers in the UK Biobank.	Nat Genet	2021
34957434	Machine learning enables new insights into genetic contributions to liver fat accumulation.	Cell Genom	2021
32833571	How Will Machine Learning Inform the Clinical Care of Atrial Fibrillation?	Circ Res	2020
31691645	Monogenic and Polygenic Contributions to Atrial Fibrillation Risk: Results From a National Biobank.	Circ Res	2020
32164899	Titin Truncating Variants in Adults Without Known Congestive HeartÂ Failure.	J Am Coll Cardiol	2020
31707836	Genetic Interleukin 6 Signaling Deficiency Attenuates Cardiovascular Risk in Clonal Hematopoiesis.	Circulation	2020
32382064	Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy.	Nat Commun	2020
32827459	Menopausal age and left ventricular remodeling by cardiac magnetic resonance imaging among 14,550 women.	American Heart Journal	2020
33236004	Hematopoietic mosaic chromosomal alterations and risk for infection among 767,891 individuals without blood cancer.	Res Sq	2020