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Author Details

Mark A Mintun
Mallinckrodt Institute of Radiology , Washington University School of Medicine
1980
235
104
PMIDPaper TitleJournal TitlePublished Year
36855201Early tau detection in flortaucipir images: validation in autopsy-confirmed data and implications for disease progression.Alzheimers Res Ther2023
37600216Tau as a diagnostic instrument in clinical trials to predict amyloid in Alzheimer's disease.Alzheimers Dement (N Y)2023
37459141Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial.JAMA2023
37204338APOE ε4's impact on response to amyloid therapies in early symptomatic Alzheimer's disease: Analyses from multiple clinical trials.Alzheimers Dement2023
35260470Baseline Microglial Activation Correlates With Brain Amyloidosis and Longitudinal Cognitive Decline in Alzheimer Disease.Neurol Neuroimmunol Neuroinflamm2022
36251300Association of Donanemab Treatment With Exploratory Plasma Biomarkers in Early Symptomatic Alzheimer Disease: A Secondary Analysis of the TRAILBLAZER-ALZ Randomized Clinical Trial.JAMA Neurol2022
36094645Association of Amyloid Reduction After Donanemab Treatment With Tau Pathology and Clinical Outcomes: The TRAILBLAZER-ALZ Randomized Clinical Trial.JAMA Neurol2022
35099509Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum.JAMA Neurol2022
34155411A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease.Nat Med2021
33682705Relationships Between Cognition and Neuropathological Tau in Alzheimer's Disease Assessed by 18F Flortaucipir PET.J Alzheimers Dis2021
33720879Clinicopathological Correlation: Dopamine and Amyloid PET Imaging with Neuropathology in Three Subjects Clinically Diagnosed with Alzheimer's Disease or Dementia with Lewy Bodies.J Alzheimers Dis2021
33720637Donanemab in Early Alzheimer's Disease.N Engl J Med2021
34379934Donanemab in Early Alzheimer's Disease. Reply.N Engl J Med2021
30569813Parametric methods for [<sup>18</sup>F]flortaucipir PET.J Cereb Blood Flow Metab2020
32338734Positron Emission Tomography Imaging With [18F]flortaucipir and Postmortem Assessment of Alzheimer Disease Neuropathologic Changes.JAMA Neurol2020
30753379Tau PET in autosomal dominant Alzheimer's disease: relationship with cognition, dementia and other biomarkers.Brain2019
31476153Tau Subtypes of Alzheimer's Disease Determined in vivo Using Flortaucipir PET Imaging.J Alzheimers Dis2019
30969506Tau Positron-Emission Tomography in Former National Football League Players.N Engl J Med2019
29188296Association of Cerebral Amyloid-β Aggregation With Cognitive Functioning in Persons Without Dementia.JAMA Psychiatry2018
30006100Standardization of amyloid quantitation with florbetapir standardized uptake value ratios to the Centiloid scale.Alzheimers Dement2018
29601787Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease.Alzheimers Dement2018
29365294Trial of Solanezumab for Mild Dementia Due to Alzheimer's Disease.N Engl J Med2018
29284675Test-Retest Reproducibility for the Tau PET Imaging Agent Flortaucipir F 18.J Nucl Med2018
29099578Development of a Positron Emission Tomography Radiotracer for Imaging Elevated Levels of Superoxide in Neuroinflammation.ACS Chem Neurosci2018
29191858Flortaucipir F 18 Quantitation Using Parametric Estimation of Reference Signal Intensity.J Nucl Med2018
28064343Quantitation of PET signal as an adjunct to visual interpretation of florbetapir imaging.Eur J Nucl Med Mol Imaging2017
28365320Use of white matter reference regions for detection of change in florbetapir positron emission tomography from completed phase 3 solanezumab trials.Alzheimers Dement2017
28334939Association between tau deposition and antecedent amyloid-β accumulation rates in normal and early symptomatic individuals.Brain2017
28077397Relationships between flortaucipir PET tau binding and amyloid burden, clinical diagnosis, age and cognition.Brain2017
28374171Quantification of Tau Load Using [<sup>18</sup>F]AV1451 PET.Mol Imaging Biol2017
28721302Correlation between two methods of florbetapir PET quantitative analysis.Am J Nucl Med Mol Imaging2017
28787712Effectiveness of Florbetapir PET Imaging in Changing Patient Management.Dement Geriatr Cogn Disord2017
27908967Kinetic Modeling of the Tau PET Tracer <sup>18</sup>F-AV-1451 in Human Healthy Volunteers and Alzheimer Disease Subjects.J Nucl Med2017
26745445Effect of Amyloid Imaging on the Diagnosis and Management of Patients with Cognitive Decline: Impact of Appropriate Use Criteria.Dement Geriatr Cogn Disord2016
27151986Kinetics of the Tau PET Tracer 18F-AV-1451 (T807) in Subjects with Normal Cognitive Function, Mild Cognitive Impairment, and Alzheimer Disease.J Nucl Med2016
26936940Regional profiles of the candidate tau PET ligand 18F-AV-1451 recapitulate key features of Braak histopathological stages.Brain2016
25043833Comparison of imaging biomarkers for Alzheimer's disease: amyloid imaging with [18F]florbetapir positron emission tomography and magnetic resonance imaging voxel-based analysis for entorhinal cortex atrophy.Int J Geriatr Psychiatry2015
26414022Targeting Prodromal Alzheimer Disease With Avagacestat: A Randomized Clinical Trial.JAMA Neurol2015
26338898A Semiautomated Method for Quantification of F 18 Florbetapir PET Images.J Nucl Med2015
26180632Levodopa effects on [ (11)C]raclopride binding in the resting human brain.F1000Res2015
25988462Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis.JAMA2015
25988463Prevalence of amyloid PET positivity in dementia syndromes: a meta-analysis.JAMA2015
25652817Quantification of 18F-florbetapir PET: comparison of two analysis methods.Eur J Nucl Med Mol Imaging2015
25745095Measurement of longitudinal β-amyloid change with 18F-florbetapir PET and standardized uptake value ratios.J Nucl Med2015
25443857The Centiloid Project: standardizing quantitative amyloid plaque estimation by PET.Alzheimers Dement2015
24468015Antidepressant response to aripiprazole augmentation associated with enhanced FDOPA utilization in striatum: a preliminary PET study.Psychiatry Res2014
29255837EU./U.S. CTAD Task Force on Alzheimer's Trial Populations.J Prev Alzheimers Dis2014
24828079An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice.Sci Transl Med2014
24847866Development of a PET radiotracer for non-invasive imaging of the reactive oxygen species, superoxide, in vivo.Org Biomol Chem2014
24927705Positive florbetapir PET amyloid imaging in a subject with frequent cortical neuritic plaques and frontotemporal lobar degeneration with TDP43-positive inclusions.J Alzheimers Dis2014
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Collaborators

John C Morris
Washington University School of Medicine
Co-authored papers 43
Michael D Devous
University of Texas Southwestern Medical Center
Co-authored papers 21
David M Holtzman
Co-authored papers 21
Adam S Fleisher
Banner Alzheimer's Institute, University of California
Co-authored papers 20
Eric M Reiman
Banner Alzheimer's Institute
Co-authored papers 16
William J Jagust
Helen Wills Neuroscience Institute, University of California Berkeley
Co-authored papers 13
Marwan N Sabbagh
Barrow Neurological Institute
Co-authored papers 12
Pudugramam Murali Doraiswamy
Duke University School of Medicine
Co-authored papers 11
Carl H Sadowsky
Premier Research Institute and NOVA SE University
Co-authored papers 11
Kewei Chen
Beijing Normal University
Co-authored papers 10
Keith A Johnson
Brigham and Women's Hospital, Massachusetts General Hospital, Harvard Medical School
Co-authored papers 9
Stephen Salloway
Butler Hospital, and Warren Alpert Medical School of Brown University
Co-authored papers 9
Robert A Koeppe
University of Michigan ann arbor
Co-authored papers 8
Reisa A Sperling
Brigham and Women's Hospital, Massachusetts General Hospital
Co-authored papers 8
Alison M Goate
Icahn School of Medicine at Mount Sinai
Co-authored papers 8
Thomas E Nichols
Big Data Science Institute, University of Oxford
Co-authored papers 7
Daniel S Marcus
Mallinckrodt Institute of Radiology, Washington University School of Medicine
Co-authored papers 7
Chester A Mathis
University of Pittsburgh
Co-authored papers 7
David A Wolk
University of Pennsylvania
Co-authored papers 6
Deanna M Barch
Washington University School of Medicine in St. Louis
Co-authored papers 6
Paul S Aisen
Alzheimer's Therapeutic Research Institute, University of Southern California
Co-authored papers 6
Ralph E Coleman
Duke University School of Medicine
Co-authored papers 6
Michael W Weiner
University of California San Francisco
Co-authored papers 5
Ronald C Petersen
Mayo Clinic Rochester
Co-authored papers 5
Nigel J Cairns
Washington University School of Medicine
Co-authored papers 5
Mony J de Leon
Brain Health Imaging Institute
Co-authored papers 5
Julie C Price
Massachusetts General Hospital
Co-authored papers 4
Wolfgang Maier
University Hospital Bonn
Co-authored papers 4
Douglas Galasko
Co-authored papers 4
Carolyn C Meltzer
Keck School of Medicine of University of Southern California
Co-authored papers 4
Release 1.2